Sebastian Lourido
@LouridoLab
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Molecular parasitologist leading a lab at the Whitehead Institute for Biomedical Research & MIT. All opinions my own. 🔬🏳️🌈🇨🇴
Cambridge, MA
Joined September 2016
We’re looking for someone to lead the implementation and advancement of genome technologies at Whitehead. Spread the word! An opportunity to work with an incredible community of scientists!
Whitehead Institute, a leading biomedical research institute in Cambridge, Massachusetts, is hiring a Genome Technology Core (GTC) Director: https://t.co/aEdiMfZ5yg
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Whitehead Institute, a leading biomedical research institute in Cambridge, Massachusetts, is hiring a Genome Technology Core (GTC) Director: https://t.co/aEdiMfZ5yg
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Our parasite genome databases are really gone! The lack of communication and scientific vision @NIH is hard to follow. Colossal mistake! @parasitesrule @BSPparasitology @theNASciences @ScienceMagazine @Nature @NIAIDNews
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OUT NOW 👉 CRISPR-based functional profiling of the Toxoplasma gondii genome during acute murine infection🐁 @ChrisJGiuliano @LouridoLab @WhiteheadInst
https://t.co/ANP7tFF777
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Researchers in @LouridoLab performed the first genome-wide screen of Toxoplasma gondii in live hosts, revealing genes that are important for infection but previously undetected in cell culture experiments: https://t.co/Em4ZGCeto7
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Read more about the work in this great news article by @gretafriar for @WhiteheadInst
wi.mit.edu
Apicomplexan parasites are responsible for several prevalent infectious diseases including malaria. Whitehead Institute Member Sebastian Lourido and colleagues identified a protein complex that the...
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Thank you to our collaborators in the @VernCarruthers and Niles lab for your help in this study.
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Very excited to see this out in press. An effort led by @saimamaysidik and Dylan Valleau to understand the function of the CLAMP complex in apicomplexan parasites!
A conserved complex of microneme proteins mediates rhoptry discharge in #Toxoplasma: @LouridoLab @WhiteheadInst @MITBiology show that three #apicomplexan-specific #microneme proteins form a complex essential for #rhoptry discharge and invasion https://t.co/N9iSf0wZHl
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Very excited to share our latest study using cryo-ET to investigate actin filaments in #Apicomplexan parasites. This allowed us to learn where do these filaments originate at the cell tip and how they could be managed down the cell body to power motility! https://t.co/vNeVXkti2B
nature.com
Nature Communications - Apicomplexan parasites utilize a unique actomyosin system to mediate motility and host cell invasion. Here, the authors apply cryo-ET to Cryptosporidium parvum and...
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Like many joys in science, promotions develop slowly making it hard to know when to mark the occasion. Happy to share my promotion to Associate Professor with Tenure @MITBiology. Immense gratitude to all the lab members, colleagues, and mentors who have made this possible!
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I had an incredible time talking about parasites and our lab’s work with @jvn for their @CuriouswithJVN podcast! https://t.co/ddWPEbPSkc
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Science friends, has anyone encountered instability or toxicity from NanoLuc-containing plasmids in E. coli?. The troublesome plasmids are not supposed to express NanoLuc in bacteria, but even if they did, there are no intrinsically toxic sequences associated with its ORF.
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@LouridoLab Here is a link to anonymous links which, PIs sign the one(s) as appropriate
sites.google.com
AmoebaDB support letter CryptoDB support letter FungiDB support letter GiardiaDB support letter Helminth support letter MicrosporidiaDB support letter PiroplasmaDB support letter PlasmoDB support...
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Just signed the support letter acknowledging the immense value of ToxoDB and sister databases in research. Inviting all PIs who see these databases as fundamental omic tools to do the same. Your signature matters! @veupathdb @LouridoLab @omartheharb
https://t.co/PixjlhEXkb
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.@veupathdb is an essential resource for our field. Please join me in expressing your support for their funding renewal!
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So excited to see this out in press! Congratulation to you and your lab @ClareHardingLab!
My first senior author paper, and @AghabiDana first first author paper is now out at @NatureComms! She has all of the details (including what changed since the preprint), but thank you to everyone who helped with this paper, its been great!
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Toxoplasma gondii causes lifelong, occasionally severe infections in humans. In this news story @LiveScience , I discuss a newly discovered Achilles’ heel in the parasite that may bring scientists closer to developing a cure. https://t.co/OtrPb0EIfE
livescience.com
A single-cell parasite relies on two genes that boost each other's activity to switch into "defense mode" when attacked by the immune system.
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Thank you @KLNahas for the wonderful write-up of our work!
livescience.com
A single-cell parasite relies on two genes that boost each other's activity to switch into "defense mode" when attacked by the immune system.
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