Vikram Alva
@Vikram_Alva
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Protein evolution // MPI Bioinformatics Toolkit @mpitoolkit // prokaryotic cell-surface proteins @MPI_Bio
Tübingen, Germany
Joined December 2015
Excited to share our team's discovery on tissue-like multicellularity in archaea under mechanical compression! Led by @theopi, Olivia Leland & @Archaeon_Alex, it rethinks the evolution of multicellularity beyond eukaryotes. @HFSP @MPI_Bio .
This story started 5y ago with my lab. Spearheaded by fearless 1st authors @theopi and Olivia Leland. Theopi is now a PhD student at @BrownUniversity. Olivia is a physics PhD student at @BrandeisU, a self-taught biologist, and made us love soft matter. A (very long) thread (1/24)
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RT @diorge_souza: Happy to share the final format of our paper on Asgard ESCRT-III and the evolution of this protein family in eukaryotes!….
science.org
Asgard archaea have two ESCRT-III subunits with the conserved traits that drive stepwise membrane remodeling in eukaryotes.
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RT @HFSP: Attention researchers from all over the world🙃The Call for Letters of Intent for the 2025 HFSP Research Grants is NOW OPEN! 📢 It'….
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RT @alexrives: We’re also announcing an ESM3 compute grant pilot program for applications at the scientific frontier. ESM3 can enable creat….
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RT @Selim_Khaled_: Just an impression of what we're doing. #joboffer Plz RT & spread words. #SelimLab has open positions (#PhD & #postd….
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RT @JorgensenWL: It is very sad to learn that Martin Karplus passed away on Dec 28 at age 94. He was a scholar and pioneering chemical phys….
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Check out this cool work from @conticellolab, Egelman, & @RemautHan labs on cannulae—hollow tubules in Pyrodictium abyssi!. These resilient structures connect cells into networks, even in extreme conditions. CryoEM reveals calcium-driven assembly via donor strand complementation.
Donor Strand Complementation and Calcium Ion Coordination Drive the Chaperone-free Polymerization of Archaeal Cannulae . Happy that the preprint is now published. Great collaboration with fantastic colleagues. @conticellolab @EmoryChem.
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RT @Selim_Khaled_: Happy to share our recent collaboration with @MicroGap @Vikram_Alva & Dubnau. ComFB is a new widespread family of c-di-G….
biorxiv.org
Cyclic dimeric GMP (c-di-GMP) is a widespread bacterial second messenger that controls a variety of cellular functions, including protein and polysaccharide secretion, motility, cell division, cell...
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RT @dudin_o: #NOTtheCover.Unfortunately, we didn't make the cover @Nature. I still think our proposition deserves sharing. Enjoy the rea….
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RT @Archaeon_Alex: "Our findings about the autonomous and palindromic developmental program of C. Perkins hint that such multicellular deve….
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RT @hernanaburbano: Our review paper on the evolution of tailocins got the cover of @TrendsMicrobiol. with @Backman….
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RT @Selim_Khaled_: Independent group leader in @CoE_CMFI at @uni_tue . Can't recommend anything More . The best place to start your gro….
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RT @dudin_o: 1/9.Insanely PROUD to share our new collaborative project with @Dey_Gautam & @CentrioleLab. #PlanExM.We think (almost certain)….
biorxiv.org
Microbial eukaryotes are small and often resistant to standard labelling and imaging techniques, and therefore remain understudied – despite their critical ecological importance - with the exception...
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RT @Selim_Khaled_: Come & join us. Still some days are left. Consider to apply if it fits and wanna join our team 😉. Plz RT & spread….
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RT @bengeliscious: The final version of our PyShell🥧🐚 paper is now online @CellCellPress. Check out how diatoms soak up 20% of the Earth's….
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Excited to share our new paper in @PNASNews! 🚀 Halofilins shape archaeal cells during cell-type shifting. For details, check out Alex's threads! Huge thanks to @PohlschroderLab, @SchmidLab, and great team at @BissonLab. Read more: @MPI_Bio.
New paper online @PNASNews! Great collab with @Vikram_Alva, @PohlschroderLab, @SchmidLab and inspiring team work within the Bisson lab. PNAS: Preprint: Blurb: highlights below (1/4)
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RT @Selim_Khaled_: #joboffer Plz RT & spread words. #SelimLab has open positions (#PhD & #postdoc available immediately) with focus on stru….
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