Michael Galperin Profile
Michael Galperin

@MicroGap

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Bacterial signaling, c-di-GMP, c-di-AMP, protein domains NCBI's Comp. Bio. Branch, COG database, J. Bacteriology

Bethesda, MD
Joined May 2016
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@MicroGap
Michael Galperin
5 days
The interactions of c-di-GMP with the acidic residues seen in the MshEN domain could be quite widespread Protonated Glutamate and Aspartate Side Chains Can Recognize Phosphodiester Groups via Strong and Short Hydrogen Bonds in Biomacromolecular Complexes.
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@MicroGap
Michael Galperin
5 days
An interesting discussion: .c-di-GMP does not bind H-NS, nor inhibits H-NS binding DNA | Nat. Comm (PMID: 40506437).Reply to: “c-di-GMP does not bind H-NS, nor inhibits H-NS binding DNA” | Nat. Comm (PMID: 40506445).
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@MicroGap
Michael Galperin
19 days
Lee Kroos et al. (17 authors) .From the humblest of beginnings (i.e. a pile of dry cow dung) over 80 years ago, the Gram-negative bacterium Myxococcus xanthus has emerged as a premier model system for studying diverse fields of bacteriology
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@MicroGap
Michael Galperin
19 days
RT @apbrogan: Very happy to share that a large part of my thesis work is out today: B. subtilis uses the second messenger c-di-AMP to modul….
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@MicroGap
Michael Galperin
22 days
In the architecture of the outer membrane complex PelBC for Pel export, the essential periplasmic ring of twelve PelC lipoproteins is mounted on top of the PelB β-barrel.
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@MicroGap
Michael Galperin
22 days
In Bacillus subtilis, c-di-AMP levels are modulated by the cyclase regulator CdaR in response to cell wall defects. Great work by @apbrogan.bsky.social et al.
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@MicroGap
Michael Galperin
1 month
This paper offers a solution to a long-standing problem: .A general mechanism for initiating the bacterial general stress response | eLife @nielsbradshaw .
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@MicroGap
Michael Galperin
3 months
RT @Selim_Khaled_: We cracked the mystery: Pteridines are the natural ligands of CutA, a widespread protein in nature.@HHU_de @CoE_CMFI. I….
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@MicroGap
Michael Galperin
3 months
Novel families of selenoproteins.
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@MicroGap
Michael Galperin
3 months
Congratulations, @shuramankin!
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@MicroGap
Michael Galperin
3 months
RT @miguel_matilla: Congratulations to my former postdoc supervisor, Prof. George Salmond. A well-deserved recognition! @MicrobioSoc. https….
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@MicroGap
Michael Galperin
4 months
RT @JustinSextonIN: I know one thing. Zelenskyy would’ve received a hero’s welcome from these guys, and sent home with enough ammo to go a….
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@MicroGap
Michael Galperin
4 months
Hyperpiliation reduces Pseudomonas aeruginosa pathogenicity
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@MicroGap
Michael Galperin
4 months
Pyruvate kinase of Bacillus subtilis produces GTP ~10 times more efficiently than ATP
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@MicroGap
Michael Galperin
5 months
Tweet media one
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@MicroGap
Michael Galperin
5 months
RT @biorxiv_micrbio: The architecture, assembly, and evolution of a complex flagellar motor #biorxiv_micrbio.
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@MicroGap
Michael Galperin
5 months
Treponema pallidum cells and DNA are now available from DSMZ.
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@MicroGap
Michael Galperin
5 months
RT @ASMicrobiology: Correct link
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@MicroGap
Michael Galperin
5 months
RT @ASMicrobiology: TfpY is a conserved accessory protein found in type IV pili (T4P)-expressing bacteria. While T4P are often phage recept….
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@MicroGap
Michael Galperin
5 months
RT @miguel_matilla: Formate-specific chemoreceptors and their evolution in bacteria. Very grateful to be part of this multidisciplinary and….
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