This story started 5y ago with my lab. Spearheaded by fearless 1st authors @theopi and Olivia Leland. Theopi is now a PhD student at @BrownUniversity. Olivia is a physics PhD student at @BrandeisU, a self-taught biologist, and made us love soft matter. A (very long) thread (1/24)

We’re excited to announce the incredible speaker line-up for the Prokaryotic Cell Biology Conference! Join the leading researchers as they explore the latest advances in Nanoimaging, Cell Growth and Cellular Structures. Join our speakers & register today!

After lots of testing, finally releasing magnetic beads for RNA purification

It is exciting to see how biophysics, cell biology, and systems biology are co-evolving as a field. Tech allows fast orthogonal data collection across conditions, moving away from "genetic pathway <-> function" and phenotypes alone can connect genes/proteins to mechanism (4/4)

Changed the biochemistry (pH, salt, substrate...)? Mechanics (osmolarity, electrical/magnetic field...)? Developmental program? Yeah, you are likely changing all the other outputs and shifting "bottlenecks". That's part of the "noisy" natural selection process (3/4)

Cell wall synthesis? Turgor fluctuations (periplasm and cytoplasm)? Membrane tension? Assembly of the cytokinetic ring? FtsZ treadmilling itself? The answer is: it does not matter because these are moving pieces, and physiological conditions are coupled with cell mechanics (2/4)

This is one of my fav bac cell div papers. It's remarkable how much we've learned about cytokinesis in the past decade, and how much we still don't know. This paper harmonizes many of the disagreements in the field, like what limits construction rates (1/4)

Alright fellas. Come one come all, #amateurbiology poster presentation at #asmicrobe on our first set of methylation screening results on Halococcus. Come ask about an exciting new finding I couldn't put on the poster! #archaea EEB 1147 @kmaclea @Archaeon_Alex

Out Now! An atypical Arp2/3 complex is required for Plasmodium DNA segregation and malaria transmission https://t.co/r4su1H8xQU #MalariaResearch #Plasmodium #DNAsegregation

"We thank the reviewers for their helpful comments"

What it has become a classic review every ~5 years by the Polschroder (UPenn) and Schulze (RIT) labs, showing how the improvements in the techniques used in Mol and Cell Bio model Haloferax volcanii , the "E. coli" of the Archaea.

Who would ever imagine that tariffs would hit the American market, not the companies?

Apart of the sad week, I want to celebrate my quick but inspiring trip to UIUC, home of Archaea. I was gifted the nicest thing I ever owned: a set square that belonged to Ralph Wolfe, pioneer of methanogenic Archaea TY, Abigail Finn and Chemical Biology Fellows. You're +++

🎉🎉We’re on the cover of @NaturePhysics!! Here is the original paper https://t.co/OXExuoqGFt

Making a heatmap is an essential skill for a bioinformatician. But you probably do not understand heatmap. 7 reading resources to understand heatmap! 🧵

Is the genome just a bag of genes? A new paper in @ScienceMagazine now reports that for two thirds of an organisms' genes the position along the chromosome is actually very tightly constrained! Amazing work from my favorite night scientist @MartinJLercher and his team!

Super excited our paper on circRNA stability in the brain and their use as life experience markers is out! @inespatop @kadenerlab

Dive into the world of non-model microbes with Cultivarium and ATCC! Apply for sponsorship—gain access to free strains, advanced tools & $1,000 to help accelerate your research! Apply by 5/4! https://t.co/8XriBzEJ5z @atcc #iGEM #synbio #igemcommunity

@ItaiYanai Milton Glaser, the graphic designer makes the point that personal development is inherently antithetical to professional success, an exemplar being Picasso, who was extraordinary because he regularly abandoned his accomplishments. https://t.co/NA7eplH2zg

Expert’s dilemma: An increase in a scientist’s abilities for creative interdisciplinary thinking is almost inevitably linked to a loss in expertise and thus credibility in their home field, reducing the acceptability of the work to their peers https://t.co/uLCo9bhCmA

Tissue-like multicellular development triggered by mechanical compression in archaea @Archaeon_Alex @BrandeisLS | Science