Zachary Lewis
@UgaChromatinLab
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University of Georgia
Joined December 2011
Check out the latest work from our lab by Dr. Felicia Ebot-Ojong https://t.co/cL6XjIOeo6)
biorxiv.org
Polycomb group (PcG) proteins form chromatin modifying complexes that stably repress lineage- or context-specific genes in animals, plants, and some fungi. Polycomb Repressive Complex 2 (PRC2)...
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Congrats to our newest Genetics PhD, Dr. Felicia Ebot-Ojong! Here Felicia is with her advisor Dr. Zack Lewis @UgaChromatinLab Felicia will start a position at the Van Andel Institue @VAInstitute with Dr. Peter Laird @peterwlaird We are proud of you Dr. Ebot-Ojong!
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have you ever gazed out at some fungus and wondered what else could be in there?✨ Check out our new @TrendsGenetics review on fungal #Starships 101: what we know so far and where we think the field is headed. Great job Andrew and @Hulk_Vogan 🍄🚀 https://t.co/pED1u073PK
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Congrats to the 2024 recipients of the FASEB CARES Award, including Lewis Lab team member Felicia Ebot-Ojong!! @uga_genetics
https://t.co/MSkybTLict
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https://t.co/60lgyKrNn9 - plospearl on chronic fungal infections from @thehoganlab in @PLOSPathogens
journals.plos.org
To manage and treat chronic fungal diseases effectively, we require an improved understanding of their complexity. There is an increasing appreciation that chronic infection populations are often...
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Excited to share our latest work investigating the consequences of extant genetic variation in cis-regulatory elements at single-cell resolution. A short 🧵 https://t.co/fdq9U83Csf
biorxiv.org
Gene expression and complex phenotypes are determined by the activity of cis -regulatory elements. However, an understanding of how extant genetic variants affect cis -regulatory activity remains...
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Context-specific functions of chromatin remodellers in development and disease https://t.co/BcDFUzZpYf
#Review by @saigourisankar, @AKrokhotin, @wendywenderski & Gerald R. Crabtree @Stanford
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The Lewis Lab at UGA is searching for a research technician to support two NIH-funded projects. You can learn about our work at https://t.co/eXyUsoPNzW. Apply here:
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Our latest paper on adenine and cytosine methylation in Mucoral fungi just appeared in @NatureComms. This is a collaboration between us, Victor Garre’s group at U Murcia (Spain), @jgi and many other amazing colleagues. https://t.co/SJXuZeiy3j
nature.com
Nature Communications - Here, Lax et al characterise the role and distribution of an epigenetic mark, adenine methylation (6mA), in the genomes of early diverging fungi and find the enzymes that...
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We need antibodies to a Neurospora protein. Can anyone recommend an affordable peptide synthesis/antibody production service?
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Do fungal Starships 🚀 matter for human health? We dive into the pathogen Aspergillus fumigatus and connect the dots between these unusual transposons and strain variability. Spoiler alert: biofilms, secondary metabolites and intra-strain variation, oh my!
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Our new review is out in First Look: Paths of least resistance: Unconventional effector secretion by fungal and oomycete plant pathogens
apsjournals.apsnet.org
Effector secretion by different routes mediates the molecular interplay between host plant and pathogen, but mechanistic details in eukaryotes are sparse. This may limit the discovery of new effect...
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Reliable protein-protein docking with AlphaFold, Rosetta, and replica-exchange. https://t.co/c952NUWEQB
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Congratulations to Dr. Jennifer Loros on being recognized by the neurospora research community for your invaluable contributions to the field!! https://t.co/50glSCk0G9
geiselmed.dartmouth.edu
Jennifer Loros, PhD, a professor of Biochemistry and Cell Biology and of Molecular and Systems Biology at Dartmouth’s Geisel School of Medicine, has received the 2023 B.O. Dodge Award from the Neur…
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“Improving protein expression, stability, and function with ProteinMPNN” Constraining inverse folding w evolutionary information https://t.co/xDzbgslyEs
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Congrats to @MareikeMM and the Freitag lab on this nice paper.
journals.plos.org
Author summary Facultative heterochromatin contains genes important for specific developmental or life cycle stages. Transcriptional regulation of these genes is influenced by chromatin structure....
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UNRAVELLING THE MYSTERIES OF HETEROCHROMATIN! Ever wonder how silenced heterochromatin domains are stably propagated? This article describes the conserved principles by which modified histones and HP1 condensates promote self-propagation of heterochromatin https://t.co/qtDwWgWo8r
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5 books that will help you build healthy academic writing habits (so you can write a lot and publish a lot):
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