Tulsi Upadhyay
@TulsiUpadhyay5
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Protein Biochemist. Postdoctoral fellow at Stanford University, California. Ph.D. from IISER Bhopal.
Joined June 2020
Excited to share my First GRS and GRC moments. It was very special #Bioorganic GRC2025. Met my PhD advisor @SaraogiIshu. Great Science and networking. Won “Outstanding Poster” award. Thanks to my postdoc advisor @mbogyo for the opportunity to present in GRC with him.
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My lab at the Department of Biotechnology, Savitribai Phule pune university will be happy to host one NPDF. If interested can contact me.
📢 #ANRFIndia Invites Applications for National Post-Doctoral Fellowship (NPDF)! Shape your research journey with support from @ANRFIndia 🗓️Application Period: 1 June 2025 – 30 June 2025 🔗For more, visit: https://t.co/rWtJMZyW8R
#researchgrant #NPDF
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I'm thrilled to share the news that my second paper from postdoc work is now published! A heartfelt thank you to my PI, Prof. Bogyo @mbogyo for his unwavering support throughout this project. I'm also grateful to our fantastic collaboration team for making it a great success.
Our work identifying new covalent inhibitors of Staphylococcus aureus serine hydrolyses from fragment libraries is out! great work by @tulsiupadhyay.bsky.social and our many collaborators, including @christianslentz.bsky.social, @mfellnerlab.bsky.social. https://t.co/D0zrFe95Hz
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Our work identifying new covalent inhibitors of Staphylococcus aureus serine hydrolyses from fragment libraries is out! great work by @tulsiupadhyay.bsky.social and our many collaborators, including @christianslentz.bsky.social, @mfellnerlab.bsky.social. https://t.co/D0zrFe95Hz
link.springer.com
Nature Communications - Staphylococcus aureus is a leading cause of bacteria-associated mortality worldwide. New tools are needed to both image and treat this pathogen. We previously identified a...
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💥SIDD-2025 , 24-26 March, Welcomes you all to a Students' Special Interactive Session' with Eminent Academicians and Industry Experts! Haven't Registered yet? Go Ahead & Register: https://t.co/qvjmRABebR WEBSITE: https://t.co/rBtn9XWGN2
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If you are unsure about pursuing PhD at this stage, I am also hiring 1–2 JRFs with a background in organic chemistry. We have the funding and will train you in dye/click chemistry for applications in biology. Follow the website for details
dyecraftlab.com
Chemical biology lab working with fluorescent tools for imaging, cell bology, and neuroscience
If making chemical tools for biology excites you, consider applying to the NCBS graduate program! My lab plans to hire 1–2 graduate students this cycle. More info on my lab @
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Regarding increasing the upper age limit of Scientist C in CSIR from the existing 32 years to 35 years (which is exactly the demand of research scholars), the expert Committee constituted to review the RRs has recommended to increase the upper age limit to 35 years. The agenda
Request for Revision of Age Limit (32 Years) for Scientist Positions in CSIR Institutions @DrJitendraSingh Indian researchers urge @CSIR_IND to revise the age limit for scientist positions to ensure fair opportunities for early-career scientists #ScienceForIndia #AgeLimitReform
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Check out our latest work identifying covalent fragments as inhibitors of the Fph serine hydrolases in S. aureus. Great work from @TulsiUpadhyay5 and our many collaborators.
researchsquare.com
Staphylococcus aureus is a leading cause of bacteria-associated mortality worldwide. This is largely because infection sites are often difficult to localize and the bacteria forms biofilms which are...
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After a lot of work by @SijieWang5 to finish the project I started while at Genentech on sabbatical last year, we have finally posted the results to bioRxiv.
biorxiv.org
Staphylococcus aureus ( S. aureus ) is an opportunistic human pathogen that causes over one million deaths around the world each year. We recently identified a family of serine hydrolases termed...
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New article out in Comm Biol by 1st authors @HiraJonathan and Bhupender Singh. Check out if interested in a) Cellular phenotypic heterogeneity in bacterial pathogen populations & how cell individuality shapes pop. behavior b) S. aureus c) new applications for chemical probes.
Phenotypic profiling detects differential cultivability and antimicrobial susceptibility in isogenic, but phenotypically heterogenous bacterial populations. @ChristianSLentz, @cans_uit
https://t.co/VfjDlUCB2R
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Our paper using mixed alkyl aryl phosphonates to identify serine hydrolases in Plasmodium falciparum that are potential drug targets is out. Great work from @ChemBio_John and collaborations with @fidocklab. Free Download here - https://t.co/b4SNq0PS9G
https://t.co/S6m7d0cInJ
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The published version of our bioRxiv paper is now out and open access! Check it out to learn about our efforts using fluorescent polymer-based iBody probes for image guided surgery applications.
pubs.acs.org
Fluorescence-based contrast agents enable real-time detection of solid tumors and their neovasculature, making them ideal for use in image-guided surgery. Several agents have entered late-stage...
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Activity-based protein profiling of serine hydrolases and PBPs in Enterococcus faecium https://t.co/1yJ5nEl1kg . Great work led by @jeanette_sg identifying 11 druggable, largely uncharacterized SH. Conserved activity patterns across Ef and E. lactis. @CANS_UiT @HegstadKristin
academic.oup.com
Using a chemical proteomics approach we compared enzyme activity profiles across different Enterococcus faecium strains and growth conditions and identifie
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Check out our latest preprint on the exciting work led by @Jalal_UiT identifying Klebsiella pneoumoniae hydrolases with roles in host-pathogen interactions. Thanks to all collaborators including @Mfellnerlab @mbogyo, @TulsiUpadhyay5 @MonaSusanJohan1 and others not on X.@cans_uit
🎉 Excited to share my PhD work's preprint on ABPP of Klebsiella pneumoniae hydrolases! Identified 10 serine hydrolases, spotlighting new anti-virulence targets! Huge thanks to everyone involved, especially @ChristianSLentz😌Great collaboration! @CANS
https://t.co/z7VpuZO8lO
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Thank you, @HHMIJanelia, for organizing such an insightful chemical biology conference and giving me the opportunity to present our work. I'm looking forward to more such events.
Thank you to everyone joining us @HHMIJanelia for the third iteration of our Chemical Tools for Complex Biological Systems meeting #chembio #cellsignaling #imaging #cellbio #biochemistry
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Structures just released https://t.co/02mOEJW0zc
https://t.co/Psyt4YE0y0 determined in collaboration with @Stanford @mbogyo and my lab at @OtagoBiochemist - JACS paper on Probes for Specific Detection of Staph Infections https://t.co/tsUazuuCBr
@JeyunJo @TulsiUpadhyay5 +others
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Development of Activity-Based Probes Targeting FphE for Specific Detection of Staph aureus Infections | Journal of the American Chemical Society @mbogyo @JeyunJo
@TulsiUpadhyay5 @Stanford @StanfordMed @NYTScience #Detection #StaphAureus #Infections
pubs.acs.org
Staphylococcus aureus (S. aureus) is a major human pathogen that is responsible for a wide range of systemic infections. Since its propensity to form biofilms in vivo poses formidable challenges for...
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Thrilled to share the news!! Thanks Matt @mbogyo, for giving this fantastic opportunity to work on this project. Enjoyed teaming up with @JeyunJo, @MFellnerLab and all our collaborators 🙌 Thanks @ec_woods, @NikkiPedowitz, @SijieWang5 for helping us with this project!!
Check out our latest covalent probes for imaging Staphylococcus aureus infections published @J_A_C_S. Great work from @JeyunJo and @TulsiUpadhyay5 and collaborators.
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Check out our latest work on Plasmodium with @fidocklab where we explored a novel set of mixed alkyl/aryl phsophonates as tool compounds to identify and probe essential lipid metabolizing serine hydrolases and pathways within the parasite.
Our latest collaboration with @fidocklab is out. PhD student @ChemBio_John found mixed aryl/alkyl phosphonates that target essential serine hydrolases in Plasmodium falciparum. They kill parasites with low overall induced resistance.
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Heartiest congratulations @SaraogiIshu ma'am👏👏👏👏
Congratulations to Dr. Ishu Saraogi, Associate Professor, Department of Chemistry has been awarded the Professor Dhananjay Nasipuri Memorial Lecture Award by the Indian Chemical Society. @EduMinOfIndia
@IndiaDST
@serbonline
#iiserb #achievements #chemistry #recognition
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