Triantafyllos Stylianopoulos
@TriantafyllosS4
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Associate Professor and Head of the Cancer Biophysics Laboratory, University of Cyprus
Cyprus
Joined January 2021
new article from our @Cancer_Bio_Lab in collaboration with @FotosMpekris and Cyprus Institute of Neurology and Genetics!.
New Research: Synergistic mechanotherapy and sonopermeation guided by mathematical modeling for solid tumor treatment #FrontiersIn #DrugDelivery.
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RT @MGHSteeleLabs: New publication Alert! We developed a mathematical model to decipher how the gut microbiome shapes cancer immunotherapy….
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Mathematical Modeling and Association Analysis Deciphers the Impact of the Gut Microbiome on Cancer Immunotherapy .A new study from @MGHSteeleLabs , @Cancer_Bio_Lab and @MDAndersonNews , @UCYOfficial, @harvardmed with @lancemunn, Rakesh K Jain, Jen Wargo!.
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RT @MGHSteeleLabs: Dr. Rakesh Jain @SteeleLabsMGH shared insights from his decades-long work on vascular normalization—from concept to clin….
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RT @MGHSteeleLabs: Honored to celebrate Dr. Rakesh Jain’s inspiring AACR 2025 Lifetime Achievement Award! 🏅 His keynote on “Normalizing the….
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RT @MGHSteeleLabs: How can AI and math modeling transform cancer therapy?.Our latest review @NatureRevCancer explores how mechanistic model….
nature.com
Nature Reviews Cancer - Here Harkos et al. review the role of continuous models and discrete models in predicting and understanding therapy delivery and efficacy in solid tumours. They propose ways...
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RT @JCRnEDITORS: Sonopermeation combined with stroma normalization enables complete cure using nano-immunotherapy in murine breast tumors.….
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Normalization strategies can lead to complete cure in murine breast tumor models. New article of our @Cancer_Bio_Lab in @jc.Sonopermeation combined with stroma normalization enables complete cur.
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RT @JCRnEDITORS: Bone marrow vessels are hyperpermeable to macromolecules and nanoscale medicine in a size-dependent manner. | Kazunori Kat….
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Exciting news! My @ERC_Research Advanced grant started today, at the same time that we are moving to our new buildings of the @UCYFaE , which will bring our @Cancer_Bio_Lab to the main campus of the University.
cordis.europa.eu
Cancer progression is closely associated with generation of mechanical stresses that cause the compression of tumor vessels, drastically reducing delivery of drugs. My co-workers and I found that...
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new article from our @Cancer_Bio_Lab on the mechano-pathology of solid tumors!.
frontiersin.org
The mechanical properties of the tumor microenvironment (TME) undergo significant changes during tumor growth, primarily driven by alterations in extracellul...
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RT @NatureRevCancer: #REVIEW 🚨 .@TriantafyllosS4 & Rakesh Jain & Co review the utility of continuous models & discrete models in therapy d….
nature.com
Nature Reviews Cancer - Here Harkos et al. review the role of continuous models and discrete models in predicting and understanding therapy delivery and efficacy in solid tumours. They propose ways...
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Use of math modeling and AI can improve delivery and efficacy of cancer therapies. New article of our @Cancer_Bio_Lab at @UCYOfficial in collaboration with @MGHSteeleLabs , @harvardmed published in Nature Reviews Cancer.
nature.com
Nature Reviews Cancer - Here Harkos et al. review the role of continuous models and discrete models in predicting and understanding therapy delivery and efficacy in solid tumours. They propose ways...
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RT @naturemethods: From the teams of @hadi_nia, Rakesh Jain and Lance Munn, this Review defines the four physical hallmarks of cancers and….
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Mathematical modelling of tumor growth, angiogenesis and immune response utilizing discrete and continuous modelling approaches. Research supported by @ERC_Research .
nature.com
npj Biological Physics and Mechanics - Hybrid model of tumor growth, angiogenesis and immune response yields strategies to improve antiangiogenic therapy
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RT @CommsBio: Inhibiting autophagy with hydroxychloroquine improves oxaliplatin efficacy in pancreatic tumors, when combined with losartan….
nature.com
Communications Biology - Inhibiting mechanically induced autophagy with HCQ improves oxaliplatin efficacy in pancreatic tumors, especially when combined with losartan. This combination, not only...
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Mechanical forces induce drug resistance in PDAC. Targeting the underlying mechanisms can improve therapeutic outcomes. Research supported by @ERC_Research .
nature.com
Communications Biology - Inhibiting mechanically induced autophagy with HCQ improves oxaliplatin efficacy in pancreatic tumors, especially when combined with losartan. This combination, not only...
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RT @ERC_Research: Why cancer cells are so resistant to chemotherapy?. @TriantafyllosS4 @UCYOfficial is investigating intracellular mechanis….
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Full article: Fixation alters the physical properties of tumor tissue that regulate nanomedicine transport
tandfonline.com
To have the desired therapeutic effect, nanomedicines and macromolecular medications must move from the site of injection to the site of action, without having adverse effects. Transvascular transp...
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