Jacqui Shields
@Toastyjac
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Science geek (@Shields_lab) | UoN BDI | terrible runner | sloooow biker
Joined May 2016
RT @Corrado___M: "How can integrating lymphoid tissues into biofabrication enhance 3D tumor models? .Our latest review explores how this ap….
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RT @junedh_amrute: In @Nature we use single cell multiomics, fibroblast fate tracing, and in vivo models to characterize immune fibroblas….
nature.com
Nature - A fibroblast lineage marked by FAP gives rise to POSTN-expressing fibroblasts resembling matrifibrocytes and IL-1β regulates FAP/POSTN fibroblast specification by directly signalling...
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Wow.
🗨️ WANNA TALK TO YOUR CELLS? Try out CellWhisperer – our new multimodal AI that turns single-cell RNA-seq analysis into a conversation. No coding needed, just chat in plain English. Short walkthrough below. Web app & bioRxiv preprint linked in the thread. Let's dive in! (1/9)
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RT @shouval: 📢 Hot off the press! CAFs are major regulators of the immune tumor microenvironment. In our new review we dissect a fascinatin….
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RT @socmucimm: Fibroblasts and monocytes interact to mediate fibro-stenosis in #Crohns disease in this work from SMI member Gianluca Matteo….
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RT @immunonoah: Recipient tissue microenvironment determines developmental path of intestinal innate lymphoid progenitors. Congrats to Paul….
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RT @BristolRenal: Secure your spot now! Early Bird offer for #BMVBS24 meeting ends on 7th June. Register for #BMVBS24 and the separate Endo….
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RT @TheMarkFdn: Apply now! @EACRnews and The Mark Foundation have teamed up to support outstanding postdoctoral researchers in Europe with….
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RT @UoNresearch: Join the fully funded @nottm_bbsrc_dtp doctoral program for UK professionals to research biotechnology, pharmaceuticals, a….
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RT @UoNresearch: Join the fully funded @nottm_bbsrc_dtp doctoral program for UK professionals to conduct research in biotechnology, pharmac….
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RT @WTKLAB: I am pleased to share the final version of our Human Breast Cell Atlas with @MarioniLab now out @NatureGenet. There are importa….
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RT @NatureAging: Online now! The loss of HAPLN1 in aged skin fibroblasts drives melanoma progression by increasing ICAM1 and angiogenesis.….
nature.com
Nature Aging - Older age is associated with worse outcomes for patients with melanoma, and the underlying mechanisms are incompletely understood. Here the authors show that the loss of HAPLN1 in...
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RT @UoNPressOffice: Prof Nigel Mongan @UoN_BDI @Nottinghamvets @UoNFacultyMHS will lead a group of scientists as part of team SAMBAI to ta….
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The 2024 BBSRC DTP PhD programme is open! Interested in understanding how cancer treatments impact immunity? We have a 4 yr fully funded project available. Get in contact and get applying.
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Some wonderful fully-funded projects available as part of a fab programme - including one with @Shields_Lab and @andyogenesis! Get in contact and definitely get applying! Deadline 5th Jan @MedicineUoN .
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RT @lotte_dewinde: Our review on Cancer-on-chip models for metastasis is out @TrendsinBiotech discussing importance of ECM, vasculature and….
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RT @FrezzaLab: In vivo macrophage engineering reshapes the tumor microenvironment leading to eradication of liver metastases: Cancer Cell h….
cell.com
In this study, Kerzel et al. describe a lentiviral vector platform to selectively engineer liver macrophages to deliver IFNα to liver metastases from within the tissue achieving therapeutic efficacy....
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RT @Stromal_Immunol: Beautiful new study of CAR-T therapy targeted at prostate cancer cells, enhanced with carboplatin to hit the TME. Comb….
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