Corrado Mazzaglia
@Corrado___M
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Research Associate @Cambridge_Uni // Bioengineering // Cancer immunology
Cambridge, England
Joined June 2018
"How can integrating lymphoid tissues into biofabrication enhance 3D tumor models? .Our latest review explores how this approach could improve insights into tumor-immune interactions and cancer progression. Read more here:
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Very happy to share our latest paper! š In collaboration with @Biointerface_CU and @Shields_Lab Lab, we developed a 3D hydrogel-based model of a lymph node. The paper is out on Advanced Healthcare Materials - link to the open access paper:
advanced.onlinelibrary.wiley.com
Mazzaglia etĀ al. describe an in vitro lymph node model (eLN), which replicates cellular and organizational features of the murine lymph node, incorporating primary lymphocytes, fibroblastic reticul...
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RT @HafsaMunir11: The Munir Lab is looking to recruit an enthusiastic Biology Laboratory Assistant. If you're interested in skin cancer andā¦.
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RT @Cambridge_Eng: Researchers have developed a #3Dbioprinter for #CancerResearch that can be folded into a carry-on pack, transported, & eā¦.
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Traditional 2D systems fail to fully capture the TME. Our approach creates a densely packed environment that includes CAFs & immune cells, offering a possible alternative to recreating TME architectures, adaptable for different tumour types. #Biofabrication.
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Our setup is affordable & mobile, enabling wider accessibility to researchers. With our approach, we can add immune cells to the core-shell tumoroids, creating a multi-compartmental model to study therapy responses, like anti-CTLA4 immunotherapy.
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Very happy to share our new work on #3DBioprinting! Thanks to the collaborative effort between @Biointerface_CU and @Shields_Lab. 1/ We generated 3D printed core-shell tumoroids that accurately mimic the complexities of the #tumormicroenvironment.
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RT @arduino: A @Cambridge_Eng team has developed a hackable, multi-functional 3D printer for soft materials.
eng.cam.ac.uk
Researchers have developed a hackable and multi-functional 3D printer for soft materials that is affordable and open design. The technology has the potential to unlock further innovation in diverse
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RT @Cambridge_Eng: Introducing ' ā the future of #3Dprinting for soft materials:. *Hackable.*Multi-functional.*Affā¦.
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It was really exciting learning so much and sharing my work today in such a lovely place @Biofab2022
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RT @Biointerface_CU: Building/ DIY a multi-functionalš«§ Soft & Bio material šprinter for Ā£1k! check out our latest paper, led by @iekmanleiā¦.
nature.com
Scientific Reports - A hackable, multi-functional, and modular extrusion 3D printer for soft materials
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RT @JenniferALewis1: Congratulations to John Ahrens, @SebUzel and @mascott85 for leading this work, which builds on earlier work from our lā¦.
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RT @EMBLBarcelona: Welcome to #EMBOBuildNetworks!. @TinaHaase3 introduces this 3-day event. Looking forward to many exciting discussions oā¦.
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RT @Biointerface_CU: Happy to share our new work š¬ with @Shields_Lab: .Simulating the Tumor Microenvironment for Immune Cell Interactions vā¦.
biorxiv.org
Three-dimensional (3D) bioprinting has emerged as a promising tool for constructing tumor microenvironments (TME) for cancer modelling in vitro . Realizing the translational impacts of 3D bioprinting...
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RT @iekmanlei: Very glad to see this work coming out. Cell migration plays an important role in physiological and pathological processes, aā¦.
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RT @Biointerface_CU: š«We have made it to the front cover of Advanced Science with @JooHyeonLeeLabāØ Harnessing #Biofabrication for #organoidā¦.
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RT @Biointerface_CU: Upsizing and Shaping #airway #organoids, our article with @JooHyeonLeeLab is now available in the Health, Medical andā¦.
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RT @TanentzapfLab: Virtually every aspect of the COVID vaccine, from the lipid nanoparticles to the mRNA technology, was developed in acadeā¦.
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RT @Cambridge_Uni: A way to 'up-size' the #miniorgans used in #medicalresearch has been developed by a team of scientists and engineers. Iā¦.
cam.ac.uk
The researchers, from the University of Cambridge, used their method to culture and grow a āmini-airwayā, the first time that a tube-shaped organoid has been developed without the need for any
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Happy I could contribute to this exciting collaboration between @SCICambridge and @Biointerface_CU. 'Bioāassembling MacroāScale, Lumenized Airway Tubes of Defined Shape via MultiāOrganoid Patterning and Fusion'.
Delighted to share our work @AdvSciNews, a new #Biofabrication approach, MOrPF to create Macroscale #Organoid tubes towards complex airway and lung structure assembly .
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