Corrado Mazzaglia
@Corrado___M
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Research Associate @Cambridge_Uni // Bioengineering // Cancer immunology
Cambridge, England
Joined June 2018
"How can integrating lymphoid tissues into biofabrication enhance 3D tumor models? Our latest review explores how this approach could improve insights into tumor-immune interactions and cancer progression. Read more here: https://t.co/nhmHW7xzAl
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Very happy to share our latest paper! 🎉 In collaboration with @Biointerface_CU and @Shields_Lab Lab, we developed a 3D hydrogel-based model of a lymph node. The paper is out on Advanced Healthcare Materials - link to the open access paper:
advanced.onlinelibrary.wiley.com
Mazzaglia et al. describe an in vitro lymph node model (eLN), which replicates cellular and organizational features of the murine lymph node, incorporating primary lymphocytes, fibroblastic reticul...
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The Munir Lab is looking to recruit an enthusiastic Biology Laboratory Assistant. If you're interested in skin cancer and its microenvironment, please reach out. For full description & how to apply please visit https://t.co/TVXZRjB9Qb
#microenvironment #skincancer #myeloidcells
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Researchers have developed a #3Dbioprinter for #CancerResearch that can be folded into a carry-on pack, transported, & easily reassembled for printing inside a biosafety cabinet https://t.co/vqb0qVhhsT
@YaqiTKOU @Corrado___M @Biointerface_CU @Shields_Lab #biofabrication
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Traditional 2D systems fail to fully capture the TME. Our approach creates a densely packed environment that includes CAFs & immune cells, offering a possible alternative to recreating TME architectures, adaptable for different tumour types. #Biofabrication
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Our setup is affordable & mobile, enabling wider accessibility to researchers. With our approach, we can add immune cells to the core-shell tumoroids, creating a multi-compartmental model to study therapy responses, like anti-CTLA4 immunotherapy.
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Very happy to share our new work on #3DBioprinting! Thanks to the collaborative effort between @Biointerface_CU and @Shields_Lab. 1/ We generated 3D printed core-shell tumoroids that accurately mimic the complexities of the #tumormicroenvironment. https://t.co/LneyrMVqf0
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A @Cambridge_Eng team has developed a hackable, multi-functional 3D printer for soft materials.
eng.cam.ac.uk
Researchers have developed a hackable and multi-functional 3D printer for soft materials that is affordable and open design. The technology has the potential to unlock further innovation in diverse
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Introducing ' https://t.co/vSEwgL9DSK' – the future of #3Dprinting for soft materials: *Hackable *Multi-functional *Affordable *#OpenDesign Offering #design freedom & the ability to customise the print path – aiding the creation of unprecedented designs: https://t.co/Zz57RmLbXM
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It was really exciting learning so much and sharing my work today in such a lovely place @Biofab2022
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Building/ DIY a multi-functional🫧 Soft & Bio material 🍃printer for £1k! check out our latest paper, led by @iekmanlei here @Cambridge_Eng:
nature.com
Scientific Reports - A hackable, multi-functional, and modular extrusion 3D printer for soft materials
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Congratulations to John Ahrens, @SebUzel and @mascott85 for leading this work, which builds on earlier work from our lab that harnessed shear-induced alignment of anisotropic building blocks to pattern soft matter. Here, our team extends this work to organ building blocks❤️
3D bioprinting helped create this artificial heart tissue. The magnitude and direction of the contractile force depend on alignment and increase over time (see the video over 7 days). @JenniferALewis1 @Harvard @wyssinstitute @hseas Learn more: https://t.co/3RY7SDwg4F
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Welcome to #EMBOBuildNetworks! @TinaHaase3 introduces this 3-day event. Looking forward to many exciting discussions on engineering and vascular biology. Stay tuned!
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Happy to share our new work 🔬 with @Shields_Lab: Simulating the Tumor Microenvironment for Immune Cell Interactions via Deployable Extrusion Bioprinting https://t.co/VY6otOkHmy
biorxiv.org
Three-dimensional (3D) bioprinting has emerged as a promising tool for constructing tumor microenvironments (TME) for cancer modelling in vitro . Realizing the translational impacts of 3D bioprinting...
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Very glad to see this work coming out. Cell migration plays an important role in physiological and pathological processes, and it is exciting to see single cells were free to explore their different shapes in response to the various fibrillar topographies. @Biointerface_CU
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💫We have made it to the front cover of Advanced Science with @JooHyeonLeeLab✨ Harnessing #Biofabrication for #organoid and airway tube on a chip @Cambridge_Eng @AdvSciNews
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Upsizing and Shaping #airway #organoids, our article with @JooHyeonLeeLab is now available in the Health, Medical and Life Sciences virtual issue of Advanced Science #biofabrication #OAUnitedKingdom @wileyinresearch @Corrado___M @cathdabs
https://t.co/6nIKuQGXIf
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Virtually every aspect of the COVID vaccine, from the lipid nanoparticles to the mRNA technology, was developed in academic labs using public funds. But in the public's mind the credit goes to companies like Moderna/Pfizer. This is a missed opportunity to celebrate basic research
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A way to 'up-size' the #miniorgans used in #medicalresearch has been developed by a team of scientists and engineers. It's sort of a cross between baking a cake and blowing giant soap bubbles: https://t.co/EojefzyXps
@Biointerface_CU @SCICambridge @Cambridge_Eng @DeptofPhysics
cam.ac.uk
The researchers, from the University of Cambridge, used their method to culture and grow a ‘mini-airway’, the first time that a tube-shaped organoid has been developed without the need for any
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Happy I could contribute to this exciting collaboration between @SCICambridge and @Biointerface_CU. 'Bio‐assembling Macro‐Scale, Lumenized Airway Tubes of Defined Shape via Multi‐Organoid Patterning and Fusion'
Delighted to share our work @AdvSciNews, a new #Biofabrication approach, MOrPF to create Macroscale #Organoid tubes towards complex airway and lung structure assembly https://t.co/3l0ZSsaRET
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