The Davis Lab
@The_Davis_Lab
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(student-run acct) Bioinorganic physical chemistry @emorychem. Life is a movie, so we make movies to show the dynamics of metalloenzymes #PhoTonsOfFun.
Joined June 2019
Research Highlight now online: Intermolecular 1,2,4-thiadiazole synthesis by @PSeavill
https://t.co/1InovbZpNv ($) Highlighting the @J_A_C_S article by Katherine Davis, Kyle Biegasiewicz & co-workers @The_Davis_Lab @KFBChem
nature.com
Nature Synthesis - Intermolecular 1,2,4-thiadiazole synthesis
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Shout out to our undergraduate Maddie Garcia for receiving the Goldwater Scholarship!!! 🥳🎉We’re so proud of you!
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Our exploration of the fascinating enzymes behind thio/selenoimidazole antioxidant biosynthesis continues! Dive into the details here: https://t.co/hsjHvkCDM6
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Thrilled to share our preprint from an exciting collaboration with the Seyedsayamdost and Greene labs on non-canonical cytochrome P450s, including an X-ray crystal structure of the first known natively Ser-ligated P450! https://t.co/BfIpDZ7rsB
biorxiv.org
Cytochrome P450s (CYPs) are a superfamily of thiolate-ligated heme metalloenzymes principally responsible for the hydroxylation of unactivated C–H bonds. The lower-axial cysteine is an obligatory and...
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Check out our latest findings in Structure on the convergent evolution of sulfoxide synthase EgtB-IV!
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KFB Lab Alert: Congratulations to @ManiksharmaASR, @PascoeCam, and Stacey K. Jones on completing our first efforts toward using enzymatic halide recycling for intermolecular heterocycle synthesis. An awesome collaboration with @The_Davis_Lab! https://t.co/5u6QroVBQq
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That’s Dr. Ireland to you 😌 We’re so proud of our structural biology queen Kendra!!! The davis lab will miss you dearly💕
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Another month, another exciting collaboration with the Seyedsayamdost Lab! #DreamTeam
The Mo Lab discovers a new selenometabolite and confirms a selenometabolome in @NatureChem: “Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution.” Congrats Chase, Vanessa, Mo and colleagues @EmoryChem: https://t.co/vvfzUVOiVY
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Super excited for our latest collaboration with the Seyedsayamdost Lab @PrincetonChem! https://t.co/KnYtbB1986
nature.com
Nature Chemical Biology - Keratinicyclins are recently discovered glycopeptide antibiotics. Now, the mechanism of action of keratinicyclin B has been uncovered. Keratinicyclin B displays...
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Shoutout to our senior undergrad Ken on getting highest honors on his undergraduate honors thesis!!!🎉🤩
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We had a great time teaching people about protein structure and imaging techniques today at the @ATLSciFest!!! Can’t wait for next year :)
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The intrusive thoughts won in the Davis Lab today… (sorry Kira😅) Ready for @EmoryChem recruitment tomorrow 🤗
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Long-time member/friend of #ACSDBC @BookerMan_PSU has always been at the forefront of enzyme mechanism research from radical SAMs to iron-sulfur clusters. He's also worked tirelessly to support the #biochem community through service and mentoring young scientists. #BlackinChem
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@JotheBiologist Apply now to @laneygradschool summer research program, LGS-SOAR- ALL majors welcomed! #DiversityisExcellence
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Super excited to introduce our newest graduate students 🥁🥁 Welcome Jesus and Tiffany!!!🥳🎉
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Se can be incorporated into natural products, but little is known about the biosynthetic machinery involved. @The_Davis_Lab and colleagues now structurally characterize the first known Se-glycosyltransferase and selenosugar synthase. https://t.co/fdvFLwMLhv
#biosynthesis
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Happy thanksgiving from the Davis lab!!! 😋🦃🥧 Thankful for such an amazing lab :)
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KFB Lab Alert!: Our recent efforts in decarboxylative halogenation of indoles with halogenation generality, led by @HarstadLauren, has been published @ChemCommun as part of the 2023 Emerging Investigators Collection! https://t.co/IqleituBS7
pubs.rsc.org
Halogenated heteroarenes are key building blocks across numerous chemical industries. Here, we report that vanadium haloperoxidases are capable of producing 3-haloindoles through decarboxylative...
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Check out our latest publication by Kendra Ireland, where she structurally characterizes the first known Se-glycosyltransferase and selenosugar synthase!!!
pubs.acs.org
Selenium (Se) is an essential micronutrient that is found naturally in proteins, nucleic acids, and natural products. Unlike selenoproteins and selenonucleic acids, little is known about the struct...
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#OnTheBeamlines Researchers @The_Davis_Lab @EmoryChem & Yellen Lab @harvardmed are using the CLS to study fluorescent probes, molecules that could one day be used to detect and treat neurological disorders like #Alzheimers and #epilepsy. More: https://t.co/IiDOcT2OJN
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