Latest on Alternative Splicing
@SplicingNews
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Retweets of alternative splicing tweets. Fell free to tag @SplicingNews if you want some splicing-related content to be retweeted. Acoount managed by @m1quelag.
Joined April 2023
Hey all, this page and @m1quelag joined the bluesky community: https://t.co/JiKry2m3xd
https://t.co/BHcGGcc8sj
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Is splicing ✂️ making it difficult😵💫to keep track of the translated protein from your favorite gene? Not anymore... @SplicingNews
#AlternativeSplicing #Genomics #Database #scicomm #AcademicTwitter
🧵 Thread: Introducing ENACT & ENACTdb - Decoding Exon Polymorphism & Proteome Diversity #Genomics #Proteomics #AlternativeSplicing #ExonAnnotation @genomeresearch @BioinfoAdv
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Finally out https://t.co/NwSmunseCb the study (led by @xsalvatella1 & @RMendezLab) with the biophysical explanation for the profound effect of the microexon of CPEB4 as cause of autism, that we previously reported back in 2018 @ParrasAlbert @GeschwindLab @mirimiam @hervas_millan
nature.com
Nature - The molecular mechanisms of how small changes in the degree of inclusion of a neuron-specific microexon in CPEB4 lead to dominant-negative effects in the expression of genes associated...
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Online Now: Nutrient control of growth and metabolism through mTORC1 regulation of mRNA splicing https://t.co/1C5h07Ahbf
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PhD Student: Alternative splicing in auxin pathways @_kamilruzicka PhD project: characterization of auxin-related splice isoforms in Arabidopsis. https://t.co/2aKqWDdlcn
#alternative_splicing #auxin #development #plant_genetics #plant_hormones #RNA_s... https://t.co/2aKqWDdlcn
jobrxiv.org
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Interested in a #postdoc position in biomolecular #NMR? Please check out the following link for a 2-year postdoc position in my group to study RNA splicing by NMR at University of Pavia. https://t.co/dt0610prQU
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All Spliced Up Inside RNA Splicing Tee: https://t.co/XZ13C0ABqt
#allsplicedup #inside #RNA #matureRNA #introns #exons #RNAsplicing #funny #geek #humor #biotechology #biotechnologist #molecularbiology #molecularbiologist #biologyteacher #genetics #attitude
zazzle.com
Showcase the genetic engineer within with this RNA splicing design on any of these gifts. Includes wry genetics truism saying: "All Spliced Up Inside". Colorful educational diagram featuring introns...
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Assessing the Impact of Novel BRCA1 Exon 11 Variants on Pre-mRNA Splicing https://t.co/hDddJWeKSO
#mdpicells via @Cells_MDPI
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📣 Fully-funded #PhD with Prof Anthony Hall, this project applies state-of-the-art #sequencing and #computational approaches, in collaboration with leading wheat breeders, to understand how RNA splicing influences the transcriptional landscape of #wheat. https://t.co/pXz8hcYMt5
earlham.ac.uk
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Inhibition of RNA splicing triggers CHMP7 nuclear entry, impacting TDP-43 function and leading to the onset of ALS cellular phenotypes https://t.co/C6DAghg7sb
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Congratulations to Rachel Shoemaker, second-year MTB student in Dr. Dung-Fang Lee’s lab, on being awarded a CPRIT-funded BIG-TCR predoctoral fellowship! Rachel’s work is focused on p53-dysregulated alternative splicing in osteosarcoma.
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Besides transcription repression, alternative functions have been described to of #MeCP2 including transcriptional activation, #microRNA processing, #chromatin architecture and alternative splicing https://t.co/VLetZDUdIC
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📢New in GeroScience by Springer Nature Investigating the influence of the SIRT6 gene and alternative splicing on canine longevity: an in-depth bioinformatics analysis and experimental confirmation via NGS-based targeted sequencing by Özge Özmen & Gülin Köklü.
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Pigini #ASHG24 Narrowed further with those vars involved in neurological disorders, 529 pathogenic variants, 345 poison exons. Selected genes for targeted validation (about 14). Uses Prime editing, validating variant effect on poison exon splicing.
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Paolo Pigini (Mass Gen Hosp MA) #ASHG24 Defining the landscape of poison exon splicing events in the human brain: implications for neurodevelopmental and neurodegenerative disorders
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Sangermano #ASHG24 Shows diagram of exon inclusion events (GFP neg), and exon skipping events with GPF pos pools. HTSA = high throughput skipping assay. For 3' or 5' splicing errors, ref seq and var seq as combined libraries, and do RT-PCR and NGS sequence - to see alt splices
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Ramadesikan #ASHG24 Showing Firefly plot of GNAS, a tool they developed in-house. An imprinted locus; enrolled in rare disease program. RNAseq shows intron 5 variant - Shows a sashimi plot with differing splicing patterns. Evidence for exon 5 skipping.
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📣 Fully-funded #PhD with @WHaerty exploring characterisation of noise in alternative splicing. This highly collaborative project will develop skills in experimental and computational biology in a rapidly developing field. https://t.co/C5OJIFnbPv
earlham.ac.uk
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PhD Student: Alternative splicing in auxin pathways @_kamilruzicka PhD project: characterization of auxin-related splice isoforms in Arabidopsis. https://t.co/qkV40mIVu2
#alternative_splicing #auxin #development #plant_genetics #plant_hormones #RNA_s... https://t.co/qkV40mIVu2
jobrxiv.org
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