Parras Alberto
@ParrasAlbert
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@vivoarchitect CEO. Preclinical | Neuroscience | Aging | Drug Discovery | Reprogramming. Triathlete 🏊🚴♀️🏃🏿♂️
Joined December 2016
Excited to announce @vivoarchitect is live! We link global firms with Europe's best mouse preclinical facilities. Swiss precision & ethics at lower costs. Check us out: Let's innovate with integrity! #PreclinicalResearch #Mice #LifeSciences.
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Congrats @Albavalvil and @sarapico7, fantastic work! It was smart to induce reprogramming exclusively in post-mitotic cells @OcampoLab. Thrilled to have contributed to it!.
biorxiv.org
In vivo reprogramming through the forced expression of Oct4, Sox2, Klf4, and c-Myc (OSKM) has demonstrated great potential for reversing age-associated phenotypes, as the combination of these...
Happy to share our latest preprint! 🐭🧬We conducted a comparative analysis across multiple reprogrammable strains, tissues, and expression methods, presenting a comprehensive atlas for improving in vivo reprogramming research! @Albavalvil @OcampoLab .
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RT @LifespanIO: The researchers have used partial reprogramming to repair DNA damage in a mouse model. 🐭.By Josh Co….
lifespan.io
Steve Horvath, Vera Gorbunova, Alejandro Ocampo, and their team have used partial reprogramming to repair DNA damage in a mouse model. They published their findings in Frontiers in Aging. Building […]
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RT @Paddy_Barrett: Being in the top 5% of V02 Max for the population means you are 5 times less likely to die over a 10-year time horizon c….
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This great work is the result when a talented bioinformatician (@kgiperez ), an in vivo scientist (myself) collaborate under the supervision of @aocampox. Many thanks to @sarapico7 for her huge contribution during the revision and @prof_horvath and colleges!.
Latest paper from the lab where we analyze epigenetic age in multiple mouse models of premature aging. Importantly, our data reinforces the link between DNA damage and epigenetic dysregulation. Congratulations to all the authors!!.
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RT @kgiperez: Our first blog post about our journey @epiterna_ building a high-throughput screening platform for lifespan extending drugs….
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RT @OcampoLab: Great review by @trickpaine and @adanguyenx on partial cellular reprogramming. A novel rejuvenation technology with a great….
onlinelibrary.wiley.com
Partial cellular reprogramming is able to improve or restore multiple age-related phenotypes including lifespan, healthspan, epigenetic age, aging hallmarks, and tissue regeneration.
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RT @RapaNews: The new Richard Miller / ITP results are finally published on Astaxanthin and Meclizine. 12% and 8% lifespan extension respe….
rapamycin.news
Finally, the official Astaxanthin and Meclizine results and paper out of Richard Miller’s ITP program: In genetically heterogeneous (UM-HET3) mice produced by the CByB6F1 × C3D2F1 cross, the Nrf2...
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fter crafting specific instructions, I generated this image using DALL-E AI to promote our paper What do you think: am I a creator for designing it, or just a user of this AI tool?
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RT @Albavalvil: Very excited to share our Research Briefing where we discuss the latest paper from our lab regarding the “dark side” of in….
nature.com
Nature Aging - In vivo reprogramming by expression of the transcription factors OCT4, SOX2, KLF4, and MYC (OSKM factors) has been associated with early mortality and cancer. We report that these...
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RT @aocampox: New work from the @OcampoLab and members of @epiterna_ exploring the “dark side” of in vivo reprogramming. Just trying to bet….
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Impressive work! Overwhelming amount of data, made possible by the amazing team @OcampoLab. Special mention to @Albavalvil, @sarapico7, and @GDesdin.
nature.com
Nature Aging - Partial reprogramming to enhance regeneration and mitigate age-related phenotypes is limited by toxicity. Parras et al. report a transgenic reprogrammable mouse strain with...
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RT @Siftedeu: Swiss startup Epiterna has raised €10m from the Spotify founder's investment firm to develop drugs to combat the effects of a….
sifted.eu
Swiss startup Epiterna has raised €10m from the Spotify founder's investment firm to develop drugs to combat the effects of ageing.
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RT @OcampoLab: We are excited to announce @epiterna_. A spin-off from the @OcampoLab at @unil. Using a unique high-throughput drug screenin….
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RT @PCientificoAlic: Hoy han venido a conocer los servicios y espacios del #PCA y la @UA_Universidad la empresa suiza #Epiterna.👉Se dedica….
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RT @OcampoLab: We are very happy to share our last manuscript of the year describing the comparative analysis of different mouse strains of….
biorxiv.org
Over the last decades, several premature aging mouse models have been developed to study aging and identify interventions that can delay age-related diseases. Yet, it is still unclear whether these...
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RT @realNathanCheng: Another fascinating pre-print from the Ocampo Lab looking at differences in epigenetic aging across different mouse mo….
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