Simpson Lab @UWMedicine
@SimpsonLabUW
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Illuminating keratinocyte cell biology @DermatologyUW to understand epidermal differentiation/tissue homeostasis and how they are compromised in skin disease.
Joined October 2021
Thrilled to share the 1st @SimpsonLabUW research publication online @JCI_insight. We generated a pre-clinical model of Darier disease, a rare genetic skin blistering disorder that I see in my clinic and for which there are no FDA-approved therapies (1/7) https://t.co/fsyxEh2sWE
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Starting the migration to the other place, same handle @SimpsonLabUW …hoping to find the old #sciencetwitter and #dermtwitter crowds.
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Proud of med student Rafael Homer whose summer research project @SimpsonLabUW @DermatologyUW won 2nd place in the @uwsomwwami Wyoming site poster competition! Rafael also won a travel award to attend the Western Medical Research Conference & was chosen for an oral presentation🤩
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New paper from @SimpsonLabUW @DermatologyUW is online @JCI_insight🍾We found ERK hyperactivation disrupts cell-cell adhesion in epidermis, linked this pathway to both drug-induced & spontaneous Grover disease & identified MEK inhibition as a novel therapy: https://t.co/Ko48RnTxNp
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Great lunch @SimpsonLabUW @DermatologyUW for lots of celebrating including Arti’s birthday 🥳 More good news to share soon now that I’m out from under the cloud of this R01 submission 😮💨📝 ✅🤞
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Very proud of Akshata for representing @SimpsonLabUW @DermatologyUW at the @UWISCRM Fall Symposium. She did a great job at her 1st poster session explaining her work developing quantitative methods to assess our model of #HaileyHailey disease, a rare #skin #blistering disorder.
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We were sad to bid farewell to Rafael Homer, rising 2nd-year med student (left), who joined @SimpsonLabUW @DermatologyUW for the summer from the Laramie, Wyoming campus of @uwsomwwami @UWMedicine. Thanks for your work on a project to improve our understanding of #Darier disease.
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Grateful for an @american_skin1 grant to support our work @SimpsonLabUW @DermatologyUW to understand how #keratinocytes mature via #autophagy to form the outer skin layers and how this is disrupted in thick, scaly #psoriasis plaques (image from DermNetNZ). https://t.co/2oLD1kL9yl
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Thank you to @UpliftingAth Researcher Connection Program for providing a travel award for @JessicaLeeAyers from @SimpsonLabUW @DermatologyUW to attend the #Darier & #HaileyHailey Disease Symposium @SocInvestDerm mtg. Her poster was well-attended and she gave an outstanding talk!
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@SimpsonLabUW has grown over the summer so we needed two selfies🤳🤩Very proud of this group of curious & collaborative scientists all doing great work to understand skin regeneration and @RareDiseases in #dermatology while teaching me to be a better researcher, teacher & mentor.
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Fun happy hour to celebrate CJ @johnsonch20 departing @DermatologyUW to return to clinics @uwsomwwami. Special thanks to @PssfMsrf for supporting his 1-year fellowship @SimpsonLabUW. Look fwd to sharing his awesome work @ASCBiology in Dec and submitting his 1st-author paper soon!
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So proud of @UWM3D PhD student @JessicaLeeAyers (photo #2) for her awesome lightning⚡️talk @UWISCRM Symposium on her thesis project modeling #HaileyHailey disease, a rare genetic skin blistering disorder w/o any FDA-approved therapy. Making @SimpsonLabUW @DermatologyUW shine! 🤩
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Loved seeing @SimpsonLabUW members Afua Tiwaa & @uwsomwwami med student CJ Johnson do a great job explaining their projects @UWISCRM Symposium. Congrats to CJ on his poster prize! They're gearing up for oral presentations in Dallas @SocInvestDerm mtg in just 2 wks!🧫🔬🤩 #ProudPI
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Fantastic talk by @DrWoappi imagining new horizons in #regenerative #medicine for #skin. Impressive work addressing wounds which have HUGE impact on quality of life & healthcare💰 Thanks to @UWBioE for giving me a slot for a chat. Hope to see you @SocInvestDerm as a rising⭐️soon!
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Excited to share our paper @theJIDJournal w/@JennyNathans @JShendure reviewing how DNA barcoding can map cell lineages in skin development/cancer & how CRISPR-based DNA Typewriter can be used as a molecular tape-recorder to log biological signals in vivo. https://t.co/Tx6XBEnSNo
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Just 1 mo until our inaugural #Darier & #HaileyHailey Symposium convenes scientists, clinicians & advocates for these rare diseases w/o any FDA-approved drug (appealed another Rx denial for patient today). Join us pre @SocInvestDerm mtg in Dallas Tue 5/14!
Less than 2 mos until @SocInvestDerm mtg. Join us pre-mtg (Tue 5/14 @ 2pm) for a FREE inaugural symposium on #Darier & #HaileyHailey disease organized by @SimpsonLabUW @KathyGreenLab @CellJxn + fun group dinner w/another org for @RareDiseases @Pachyonychia: https://t.co/OdWprACr1d
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Inspiring spotlight from @TODAYshow on the innovative work of our lab neighbors @UWMedicine.
Dr. Nora Disis was recently interviewed by @TODAYshow correspondent @kristendahlgren as one of the top cancer researchers in the country as Dahlgren turns her focus towards The Pink Eraser Project, which will continue connecting other cancer researchers.
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Thanks again to @LEOFondet for investing in @SimpsonLabUW @DermatologyUW @UWMedicine to fund our work on Hailey-Hailey disease, a rare blistering disorder. Look fwd to our inaugural symposium on Darier & Hailey-Hailey @SocInvestDerm mtg on May 14--join us! https://t.co/dlzHGGtV7t
Improved treatment for leprosy, strategies to counter flesh-eating disease, and trial of an innovative healthcare delivery model for psoriasis. 14 illuminating projects have been awarded DKK 48 million. #skin #research #dermtwitter
https://t.co/R5l9QSO9QI
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Looking forward to attending @the_asci meeting in Chicago in April. I am very grateful for their support of the clinician-investigator pipeline through this award program that provides networking and career development opportunities for early-stage physician-scientist PIs.
The ASCI is proud to announce our 2024 Early-Career Awardees! Click here for the complete list of awardees: YPSA: https://t.co/g5Hd1vJ8Vt E-Gen: https://t.co/8EhgB8ART3 Congratulations to our awardees and to the institutions they represent!
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Excited our new grp focused on the rare genetic blistering disorders #Darier & #HaileyHailey Disease will partner w/@Pachyonychia for 2 awesome symposia before @SocInvestDerm 2024 mtg. We aim to bring together researchers & clinicians to kindle translational synergy in our field!
Registration is now open for two synergistic scientific meetings, joining forces to understand rare skin disorders & advance research & treatments for patients who suffer from these painful diseases. Learn more & register here: https://t.co/3KymzWmwgf
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Lots of fun @FlatstickPub⛳️ for @SimpsonLabUW holiday party! Not pictured is the scorecard🤫Looking forward to working with this wonderful group of scientists @DermatologyUW in 2024. Happy holidays!
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