Silvers Lab
@SilversFSU
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Research lab at Florida State University (est. 2018) studying RNA-protein complexes using solution and solid-state NMR spectroscopy. #NMR #MagLab
Tallahassee, FL
Joined May 2018
I am very excited to share our newest study published in Nucleic Acids Research on the noncanonical RNA binding in human LARP6. @OUPAcademic #RNA #LARP
https://t.co/SryPNQ80CQ
academic.oup.com
Abstract. La-related proteins (LARPs) are RNA-binding proteins that are involved in a variety of disease-related processes. Most LARPs recognize short sing
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Aducanumab binding to Aβ1-42 fibrils alters dynamics of the N-terminal tail while preserving the fibril core | PNAS
pnas.org
Aducanumab, a human IgG1 antibody with plaque-clearing effects and modest clinical benefit, binds selectively to aggregated Aβ via the N-terminal r...
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Using NMR spectroscopy, researchers at Florida State University led by Robert Silvers @SilversFSU discover new protein-RNA interaction with potential to treat fibrosis @FloridaState
https://t.co/oClk28E3mT
#NMRchat 🧲
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Have questions about applying for chemistry grad school, the admissions process, picking a school/group? Join us Wed, Nov. 5th, 8-11 pm EST. Current and former @ChemistryFSU admissions chairs, @HansonFSUand @DePrinceFSU will be doing a live Q&A on Twitch. https://t.co/yGCZLHkVmz
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Non-Canonical RNA Binding of Human La-related Protein 6 https://t.co/CT2TAWarJd
#biorxiv_biophys
biorxiv.org
La-related proteins (LARPs) are RNA-binding proteins that are involved in a variety of disease-related processes. Most LARPs recognize short single-stranded poly(U/A) motifs via a conserved hydroph...
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Excited to see our new article is out in @J_A_C_S, comparing conformational equilibria of a human GPCR in lipid vesicles, nanodiscs, and detergents. Great work from students @arka_ray1 and Beining (Kim) Jin! https://t.co/LPLOTNqTIB
#NMR #NMRchat
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We are looking for facility manager to support biomolecular solution NMR on the 1.2 GHz in the National Research Facility and collaborative research in the Department of Chemistry at the University of Warwick. To apply (deadline May 20 2025) visit:
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Tired of costly cloning software? Try IVA Prime: a free, game-changing tool for automated primer design in IVA cloning! Simplify complex cloning with one click, reduce errors, and save time. Visit https://t.co/AmYWbwd6KG.
https://t.co/4ZSF33feV6 collaboration with @JGarciaNafria
academic.oup.com
Abstract. Molecular cloning through in vivo assembly (IVA) is an efficient homology-based approach that can achieve complex cloning operations in a single
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Check out the preprint showing the role of alpha-glucans and a-amylase family enzymes in S. Pombe @Gould_Lab @PomBase #nmrchat
biorxiv.org
The fission yeast Schizosaccharomyces pombe is a widely employed model organism for studying the eukaryotic cell cycle. Like plants and bacteria, S. pombe must build a cell wall in concert with its...
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Read our latest paper on the #NMR resonance #assignment of Human LARP6 in complex with its cognate 5’SL RNA published with @SpringerNature in Biomolecular NMR Assignments!
link.springer.com
Biomolecular NMR Assignments - Human La-related protein 6 (HsLARP6) participates in the post-transcriptional regulation of type I collagen biosynthesis and is involved in the onset and progression...
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Check out our newest contribution to the expression, purification, and stability of RNase-free and binding-competent La domain of HsLARP6
pubs.acs.org
Human La-related protein 6 (HsLARP6) regulates the highly organized biosynthesis of type I procollagen polypeptides and affects the proper assembly of procollagen peptides into heterotrimers of type...
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@ChemistryFsu is searching for 3 tenure track faculty! 1. Biomaterials, 2. Molecular Bio-Design, 3. Sus & Environmental Chem. Come be my colleague! Details on our Dept page https://t.co/6TjTpAsqeG (scroll down)
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Deciphering the Binding of 5' Stem Loop RNA to the La Domain of Human LARP6 https://t.co/kjz0psSJnn
#biorxiv_molbio
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Read our latest paper on the #NMR chemical shift #assignment of Human LARP1 published with @SpringerNature in Biomolecular NMR Assignments!
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Another successful defense. Congratulations Dr. Blaine Gordon!
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Thank you to @MatthewEddyLab for inviting me present at FAME 2023. Another great year! @FLACSsection #FAME2023
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NMR Resonance Assignment of the LA Motif of Human LA-Related Protein 1 https://t.co/9WaU1efpQ1
#biorxiv_biophys
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Have questions about applying for grad school, the admissions process, picking a group? Join us Wed, Nov. 2nd, 8-11 pm ET. Current and former @ChemistryFSU Admissions Chairs, @HansonFSU and @KennemurFSU will be doing a live Q&A on Twitch. #FSU #gradschool
https://t.co/HshScUGOah
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We had a great time at #ENC2022 in Orlando! We almost convinced the Green Wing Macaw named Merlot to join the group, maybe next time! #NMR #SILVERSLAB
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