Shubhi Pandey
@Shubhip97
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Postdoctoral research associate, UF Scripps Biomedical Research Institute
Jupiter, FL
Joined June 2017
Feels great to share our findings on non canonical arrestin coupled receptors. Really happy to be a part of a terrific team led by @arshukla. Congratulations to everyone involved @MithuBaidya
@shinepunita, @the_rarejm @madhuchatur @RamanujB
@Ashu_bhu
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Congratulations @ParishmitaSarm2. Very well deserved!
Many congratulations to our fantastic superstar Parishmita Sarma @ParishmitaSarm2 @IITKanpur on winning the Sun Pharma Science Foundation Research Scholar Award!!! We are so proud to have you in our lab family, Pari !!! Keep shining & go places !!! #Amazin#Students#Proud#Mentor
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It feels good to see the discussion sections of your previous work become reality๐.. Amazing work! Many congratulations to @arshukla @CorneliusGati and everyone on the team.
Delighted to share our study on complement anaphylatoxin receptors published in Cell @CellCellPress!!! Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors: Cell
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Wishing a very happy independence day to everyone! While we have achieved a lot in past 76 years, we should not forget that we still have a long way to go.
เคฆเฅเคถ เคเค เคชเฅเคฐเคพเคจเฅ เคธเฅเค เคเฅ เคชเฅเคเฅ เคเฅเคกเคผเคเคฐ เคจเคฟเคฐเคเคคเคฐ เคจเค เคฒเคเฅเคทเฅเคฏเฅเค เคเฅ เคนเคพเคธเคฟเคฒ เคเคฐ เคฐเคนเคพ เคนเฅเฅค เคฏเฅ เคจเคฏเคพ เคญเคพเคฐเคค เคนเฅ, เคเฅ เคจเคพ เคฐเฅเคเคคเคพ เคนเฅ, เคจเคพ เคฅเคเคคเคพ เคนเฅ, เคจเคพ เคนเคพเคเคซเคคเคพ เคนเฅ เคเคฐ เคจเคพ เคนเฅ เคนเคพเคฐเคคเคพ เคนเฅเฅค
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Such a wonderful start of the day! Hang on as we are about to tell a story about #GPCR for neurotransmitter glycine. Happy Friday everybody! Work of the incredible scientist @ThibautLaboute.
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State selective macrocyclic inhibitors of Galpha s. Interesting stuff!
cell.com
Cell-permeable Gฮฑs inhibitors regulate G protein signal transduction with high nucleotide-binding-state selectivity and class specificity.
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Prof Jameel expressed his expectation frm @PrinSciAdvGoI n I support 400%. Making sure that stdnts get fellowship n PIs get fund release on time are 2 basic necessities. Can v imagine nt getting our salary on time? Then y do the scholars need to wait for what is due & deserved?
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A very informative thread. People planning to apply for a PhD position at BSBE-IITK, please go through this.
This thread is about how IIT Kanpur's BSBE Department admits PhD students. We admit PhD students twice a year - Dec/Jan and July/Aug. We call for applications from the Institute website ( https://t.co/Q8zFdgmwNy).
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Super proud of both of you.. Congratulations Pari @ParishmitaSarm2 and Shirsha @saha_shirsha!!
Such a blessing to work with this exceptionally talented duo โ Parishmita @ParishmitaSarm2 & Shirsha @saha_shirsha!!! Read their blurb published in Science Signaling @scisignal highlighting an interesting study on a novel mechanism of GPCR signaling bias. https://t.co/mV9DWuMlNQ
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What an amazing feeling to hear this from a prominent lab in the field about our recent study โโฆ your demonstration is much more convincing and this kind of highly visible paper paved the way that our next paper and grant proposal will go through peer review more easily ...โ. ๐
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That feeling can not be described in words when your PI makes a graduation hat for you with his own hands.. @arshukla I take pride in the fact that I have been mentored by you. Thanks for everything you do for all of us..
Presenting โDr.โ Shubhi Pandey!!! Many congratulations, Shubhi @Shubhip97 on successfully defending your Ph.D. thesis. Our laboratory has been truly blessed to have a student like you and we are very proud of you!!! Onwards and upwards!!!
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Our commentary in Nature Chemical Biology @nchembio highlighting the structures of the human itch receptors from Bryan Roth's @zenbrainest and Jinpeng Sun's labs. Put together by two outstanding students in our lab, Jags @the_rarejm & Pari @ParishmitaSarm2
https://t.co/xe2ZCK3z5O
nature.com
Nature Chemical Biology - Cryo-EM structures of Mas-related G-protein-coupled receptors (MRGPRs) that are involved in the allergic reaction and itch response reveal structural insights into their...
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An interesting piece of work from @SudarRajagopal group where they demonstrate different endogenous ligands of CXCR3 mediate distinct responses from different subcellular locations. Many congratulations to all involved.
Excited to share our newest preprint where we demonstrate that sustained subcellular GPCR signaling is critical to the biased signaling seen at the chemokine receptor CXCR3. A thread (1/14):
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Congratulations to @the_rarejm @RamanujBanerje5 @MinakshiBarua @BhanupriyaPani3 And many thanks to our wonderful collaborators, @THebertMcGill @t00mek88 Jana Selent and Stephane Laporte!!
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Our recent work on synthetic intrabodies as modulators of GPCR beta arrestin mediated functions is now available on BioRxiv! Many congratulations to everyone involved @arshukla @MithuBaidya @madhuchatur @Ashu_bhu @hemlata_dwivedi
biorxiv.org
Agonist-induced phosphorylation of G protein-coupled receptors (GPCRs) is a primary determinant of ฮฒ-arrestin (ฮฒarr) recruitment and trafficking. For several GPCRs, such as the vasopressin type II...
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Why stop at n=3! Many congratulations to @arshukla!! Waiting for the third one:)
When I shared the news of NASI fellowship with the lab folks last month, they said โ we want n=3. Well, the Fellowship of the Indian Academy of Sciences now makes it n=2. Many thanks and congratulations to all of you - this is a recognition of all your hard work and dedication !!
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Glad to be a part of this collaborative study highlighting the biphasic GPCR-arrestin interaction by NMR spectroscopy. Many thanks and congratulations to team @arshukla and Shimada lab.
A collaborative study involving our laboratory now published in Nature Communications describes the conformational transition during GPCR-ฮฒ-arrestin interaction using NMR spectroscopy. @IITKanpur @NatureComms
https://t.co/fBvdhzz8FN
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Here it is! Cool paper from @BShoichet and Andy Kruse lab and many others including @ahuangxp @RothLabUNC
https://t.co/CKzxvgI5gh
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Jagannath Maharana of @IITKanpur, India, is nominated in the #LabHeroes21 awards! ๐ @the_rarejm was nominated by @arshukla, @Shubhip97, @MithuBaidya, @SamanwitaMohap1 & @Monika00746461! Read Jagannath's nomination and celebrate YOUR lab heroes today: https://t.co/wIDP7N5ylL
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Can a #GPCR structure still surprise you? Happy to present #CryoEM structure of an orphan receptor GPR158. https://t.co/uTvlX803ai Couples to RGS instead of G proteins. Features an extracellular Cache domain for ligand binding Forms a unique tight dimer stapled by phospholipids
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Stay tuned for an upcoming collaborative paper in Nature Communications involving our lab @IITKanpur. We use NMR spectroscopy to probe structural dynamics of GPCR-arrestin complexes. Many congratulations to all involved including Shubhi Pandey & Hemlata Dwivedi from our lab !!!
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