SO special to hear Coach K @DukeMBB give us radiation oncologists @DukeRadOnc a personal, real talk about leadership, teamwork, & culture. As a Duke undergrad & physician, I was very hyped to meet & talk with him at length. What a legend! 17-year-old me wouldn’t believe this

@alison_tree @nickva1 @EmmaHall71 @ICR_CTSU @DrAndrewLoblaw this is incredible work! perhaps we can collaborate more as our @MoffittNews group firmly believes the same - namely that improving baseline LUTS prior to RT results in improved urinary function after RT! that’s what #pae is great for! https://t.co/veBpY30rWv

ARREST-2 opened for accrual yesterday! This is a new randomized phase 2/3 trial for patients with >10 mets that hopes to challenge the current radiotherapy paradigm for patients with polymetastatic disease. Thanks to the whole team esp @drdavidpalma and @lhscradonc @LHSCCanada

Had site initiation out West @HegiFiona for Dr Ryan McMahon's PRIME LUNG pilot @PeterMacRadOnc. 🥳 Interested in #twitterati thoughts re: trial design? hypofrac #radiotherapy or SABR to primary only in 1st line #lungcancer. Baby steps for phase III. Criticism welcome! #radonc

NCCN Breast Cancer Guidelines 2025 (v5) #update focuses on localized therapy: • Less extensive axillary surgery—SLN biopsy may replace ALND in select pts. • Hypofractionated post-mastectomy RT safe with reconstruction. • Partial breast irradiation recommended for low-risk pts

MDT management is the standard of care for early-stage lung cancer and improves survival.

A highly original epidemiologic study: in the analysis of never-smoking married couples, lung cancer risk was found to be higher in women. In other words, women may be biologically more susceptible to non-smoking-related lung cancer🤔 https://t.co/Py2c3SrDwt

Dear med students & residents: What you're learning matters, but who you’re becoming matters more. The knowledge will come, but now is the time to develop who you want to be as a clinician. Be present with patients. Get to know them. Treat them with kindness. Seek to understand.

Wow. Huge effect of fish oil on CVD outcomes for patients on hemodialysis! ‼️43% reduction in serious cardiac events ❗Significant reductions in many 2ry end points too 🐟 Standard-ish fish oil (1.6 g EPA/0.8 g DHA) 🌽 Versus corn oil placebo https://t.co/QMyeS7Ju9E

Radiotherapy plus Long-term Adjuvant Androgen Deprivation with a LHRH Antagonist Versus Agonist in with Very High-risk Localized or Locally Advanced Prostate Cancer: The EORTC GUCG-1414 Phase 3 Randomized Trial https://t.co/HJBfV4Nhwn @BertrandTOMBAL @EORTC

👎 SUPREMO manuscript is out A good example of a trial no longer really relevant to current practice -Routine ALND can be avoided post-AMAROS to save morbidity -Routine chemo not given nowadays (Oncotype etc) ~25% of T2N0 here = dilutes effect https://t.co/tQJMNXsUwf

Radiation dose in SBRT vs. Y90 in HCC. This confused me for the LONGEST time. Both measured in Gy, but clearly not the same – Y90 doses often reach 400Gy+, SBRT doses much lower (<50 Gy), yet both efficacious. Explained below. Bottom line is Y90 Gy ≠ SBRT Gy. @OncoAlert

@TonyFelefly @jryckman3 @ProtonStorey @ColtonLadbury @DrewMoghanaki @dschan02 @DrSpratticus @VedangMurthy We are extrapolating everywhere..as @jryckman3 told informed patient-guided decision making is the key. And that is why our job might be secured for next 10-15 years probably 😄. Because medicine is still an art at least in prostate cancer.

Elective Pelvic RT for Prostate Ca Alive? Dead? Comatose? Wise or voodoo? East vs West? PSMA vs Not? Answers are here! Biology trumps Bias.

When I first started in medicine idea of not using arterial line in ICU patient was seen as crazy I remember asking why we couldn't just use cuff for a few hours on particularly busy 30 hour call shift Now we know that cuff BP would've been fine because of an amazing & bold RCT

Analysis of MRI use in the diagnostic pathway for #BladderCancer. @Prof_Nick_James @ICR_London joins @UroDocAsh @MDAndersonNews to discuss the final #BladderPath trial survival analyses, demonstrating mpMRI introduced upstream of TURBT significantly improves bladder

We have become very aggressive in bacterial decolonization to help mitigate oral mucositis in head and neck radiotherapy. It is impossible to say whether both interventions at once are better than either one on their own, but anecdotally I have been pleased. They are essentially

Great to see the updated BCLC guidelines include RT! RT now incorporated into most major guidelines for HCC (BCLC, AASLD, EASL, NCCN, others) & should be a standard of care option. Full link here: https://t.co/EagzIPdmVL @OncoAlert

This is quite unexpected from a top journal… @TheLancet @TheLancetOncol Radiotherapy free is not even the point and main thrust of the paper so why the need to emphasise it as the opener of the title??? @DrewMoghanaki @_ShankarSiva @DrAlexLouie @drdavidpalma

RT for massive HCC. In series (n=156) w median tumor size 12.9 cm, local control w RT (+/- opt'l TACE) = 86%. RT dose modest (4Gy x 6-10 fx): HCC is radiosensitive. Recall in RTOG 1112, med size 7.8 cm. IMO among local HCC tx, RT/SBRT has strongest evidence for larger tumors.

Thanks for @Uromigos for letting me chat about radiation in oligometastatic RCC. @_ShankarSiva @piet_ost @ndesai2005 @KidneyCancer @AlexSherryMD @ebludmir @ASTRO_org @ACKoongMDPhD @MDAndersonNews @VedangMurthy @PavlosMsaouel @salvolarosa