🥁 Our manuscript "Multistate and functional protein design using RoseTTAFold sequence space diffusion" is finally out @NatureBiotech! 🧵b/c it's changed a LOT since preprint! . New highlights: . - High res structures. - Conditionally caged peptides. - Multistate design

RT @giannis_daras: Announcing Ambient Protein Diffusion, a state-of-the-art 17M-params generative model for protein structures. Diversity….

RT @biorxiv_biochem: De novo design of high-affinity miniprotein binders targeting Francisella tularensis virulence factor .

RT @RolandDunbrack: Maybe @Google or @GoogleDeepMind should fund CASP, given their ample resources and how much they've benefited from the….

RT @KingLabIPD: 🚨 new paper alert 🚨. Here, we designed, characterized, and evaluated >100 #malaria vaccines built on our two-component nano….

RT @BernieSanders: Mamdani won. The establishment is in panic. Billionaires are raising money against him; Trump is ranting; Islamophobes….

RT @gareofeasttown: look why would I stop at one espresso when I could have three and also a panic attack as a little bonus.

RT @BiologyAIDaily: ProxelGen: Generating Proteins as 3D Densities. １．ProxelGen introduces a new representation for protein structure gener….

RT @davidNbreslauer: 2/ Bush-crickets don’t blend in with one pigment- they build green. DBXN binds both lutein (yellow) and bilin (blue),….

RT @Lucas_Arnoldt: Current multimodal single-cell integration methods act as black boxes, lacking meaningful interpretability. We introduce….

RT @mariashriver: In a historic and unprecedented move, all of the institutions at the @NIH have signed on to and sent a letter, the Bethes….

RT @NewsfromScience: Breaking news: Staff at the National Institutes of Health have issued a declaration calling on their director to depol….

RT @Simone_Biles: @Riley_Gaines_ You’re truly sick, all of this campaigning because you lost a race. Straight up sore loser. You should be….

RT @BiologyAIDaily: Multiscale guidance of AlphaFold3 with heterogeneous cryo-EM data. １．The paper introduces CryoBoltz, a novel method tha….

RT @GabriCorso: Excited to unveil Boltz-2, our new model capable not only of predicting structures but also binding affinities! Boltz-2 is….

RT @KingLabIPD: Our very own Grace Hendricks gave an excellent talk about her work on mRNA-launched nanoparticles at the Keystone Symposium….

RT @Anthony_Bonato: Hurry up and make the Galois movie already

RT @yian_yin: 🚨New paper🚨 Excited to share our latest on @Nature today: The PIVOT PENALTY in research. More than f….

RT @njwfish: 🚨 New preprint 🚨. We introduce Generative Distribution Embeddings (GDEs) — a framework for learning representations of distrib….

RT @davidrliu: I discuss the urgent crisis from the loss of federal support of science in the US and recent clinical gene editing breakthro….

RT @grocklin: @srikosuri