Sumanth Prabhu, MD
@SDPrabhuMD
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Cardiologist and physician-scientist. Heart failure and cardio-immunology researcher. Husband and father. Guitar music enthusiast. All tweets my own.
Missouri, USA
Joined November 2015
Thoughtful editorial perspective by Ebin Johny and @ParthaDuttaLab on the importance of the spleen in healing the heart after myocardial infarction. #cardiosplenic axis!.Circulation
ahajournals.org
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Thank you @StavrosStavrak1 and the entire the cardiology group at OU for the invitation and the honor of presenting the Lazzara lecture. Appreciated the great conversations!.
š«Second Annual Ralph Lazzara Lecture at OU today.š«Featured speaker Dr. Sumanth Prabhu, Chief Cardiology Division at Wash U .š«Outstanding discussion on āInflammation & HF Revisitedā.@OUCollegeofMed .@DrDave01 .@ubcardio .@StavrosStavrak1 .@JasonKatzMD .@ShashankSinhaMD
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RT @WashUDeptMed: At @BarnesJewish time was of the essence when a patient under the care of WashU Medicine doctors Amit Pawale, MD, and Joeā¦.
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Very glad to see our recent work in press at @CircAHA . Alternatively activated macrophages driven by IL-4 signaling sustain a parainflammatory response in the failing heart. Kudos to @QiongxinWang for her tireless work on this study.
CD206āŗIL-4RĪ±āŗ macrophages proliferate and drive adverse LV remodeling via FIZZ1-mediated fibrosis. IL-4RĪ± deletion or silencing reverses remodeling and improves function. A novel therapeutic target in ischemic cardiomyopathy
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Thrilled to have our work characterizing the cardiosplenic axis after MI in press @MAIwustl @WashUCardiology @WashUDeptMed.
A specialized spleen macrophage populationāexpressing the markers CD169 and Tim4āmobilizes after MI to drive repair, clear neutrophils & reduce HF risk. A new frontier in cardioprotection via the cardiosplenic axis. @ssbansal_pshvi @SDPrabhuMD
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What constitutes the parainflammatory response in heart failure? Our latest work shows the importance of alternatively activated macrophages in driving heart failure #cardioimmunology @QiongxinWang.
ahajournals.org
BACKGROUND: The role of cardiac CD (cluster of differentiation) 206+ macrophages in chronic heart failure (HF) is unknown. We examined whether CD206+ macrophages expressing IL (interleukin)ā4RĪ± are...
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Excited to share our latest published work showing that marginal metallophilic macrophages from the spleen traffic to the heart and are required for cardiac repair after myocardial infarction. This raises the possibility of therapeutic splenic.
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A pleasure to host @pnatarajanmd as the 2025 Guller Family Lecturer at @WashUCardiology @WashUDeptMed!Outstanding overview of preventive cardiology, and the power of genome wide approaches to uncover new CV risk predictors. @GullerKeith
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Smith-Oliver reception at #AHA2024 for @WashUCardiology ! Catching up with old friends. And new ones.
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RT @AHAScience: Thatās a wrap on #BCVS24! Thanks to everyone who helped take this meeting to a whole new level. Letās meet again at #BCVSā¦.
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RT @Jess4genes: Closing Remarks for an amazing #BCVS24! Huge thanks to @FarahSheikhLab and @SDPrabhuMD . See you all at #BCVS25
https://t.cā¦.
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Congratulations to cardio-oncologist Dr. Jesus Jimenez of @WashUCardiology on winning the Outstanding Early Career Investigator Award at #BCVS24! Superb work on the effects of newer pathways for checkpoint inhibition on the heart. @LavineLab @AHAScience @FarahSheikhLab
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#BCVS2024 in full swing. Outstanding talks and posters with cutting edge science, collaboration and collegiality. A personal honor to recognize @IntMedAbel as the 2024 Keynote Speaker - he has been an inspiration to many! @FarahSheikhLab @AHAScience @JonPHeart @WashUCardiology
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So proud of our graduating @WUCardioFellows ! We canāt wait to see what you accomplish going forward. And with great appreciation for @akates1 dedication and superb leadership of the @WashUCardiology fellowship training program for the last 16 years. @WUDeptMedicine.
ā¦@WUCardioFellowsā© Farewell Celebration! My final graduating classā©! Such a wonderful group. Could not be prouder! ā¦@k_wongMDā© ā¦@RajaZaghlolā© ā¦@nicholasrarnoldā© ā¦@SDPrabhuMDā© ā¦@prathakkerā© ā¦@WashUCardiologyā©
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Honored to work on this focused review on the #cardioimmunology of #heartfailure with @PilarAlcaidePhD, @kallikourdis, and @RamonaE_91. Take a look!.
@CircRes The Interface Between #Cardioimmunology, #Myocardial Health, and #Disease Compendium Alert!. Myocardial #Inflammation in #HeartFailure with Reduced & Preserved #EF .. Authored by Drs. @PilarAlcaidePhD @kallikourdis @RamonaE_9 & @SDPrabhuMD
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šš¼!.
Check this out-many great articles on cardiac immunology - quest editors -.@ImmunoCardioLab,@DrCihakovaD,@ChristophMaack and Sumanth D. Prabhu. Interface Between Cardioimmunology, Myocardial Health, and Disease: A Compendium | Circulation Research (
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Congratulations to Sam Jordan @RentschlerLab @WashUCardiology on a terrific scientific presentation @SarnoffCardio meeting!.
Congratulations to Sam Jordan for a truly fantastic talk at the Sarnoff meeting in SF demonstrating epigenetic changes in myocytes after cardiac radiotherapy. It has been a true pleasure to have Sam in the lab, he is a star!!!
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