Rubika Balendra
@RubikaBalendra
Followers
362
Following
425
Media
14
Statuses
287
Clinical Lecturer & Neurology doctor @UCLIoN @UCLH @AdrianIsaacsLab @PataniLab, using stem cells to study motor neuron disease & dementia. Funding: @acmedsci
Joined February 2013
Check out our review on TARDBP ALS and TDP-43 proteinopathy @RickiePatani @TheLancetNeuro @TheCrick @PataniLab @JemeenSreed @martinahallegg1 @RLuisier Hilal Lashuel @jennagregory488. Thank you to all our co-authors!.
0
6
9
RT @jennagregory488: Take a look at our recent Lancet Neurology review. Amyotrophic lateral sclerosis caused by TARDBP mutations: https://t….
0
11
0
RT @FrattaLab: Out @ScienceMagazine! New tech to activate ALS gene therapies only in the right cells at the right time - Increased safety t….
science.org
Loss of function of the RNA-binding protein TDP-43 (TDP-LOF) is a hallmark of amyotrophic lateral sclerosis (ALS) and other neurodegenerative disorders. Here we describe TDP-REG, which exploits the...
0
32
0
RT @OscarWilkins16: Our paper on cryptic splicing-controlled protein expression, which we hope will inspire safer and more adventurous gene….
science.org
Loss of function of the RNA-binding protein TDP-43 (TDP-LOF) is a hallmark of amyotrophic lateral sclerosis (ALS) and other neurodegenerative disorders. Here we describe TDP-REG, which exploits the...
0
51
0
RT @Ben_ClarkeUK: Glad to see our review on the use of omics to study glia in ALS led by the superb Stan Majewski (not on X/Twitter) out in….
onlinelibrary.wiley.com
A graphical summary depicting the past and future of ALS glial research, which will require, alongside the application of molecular and cellular techniques, the utilization of more conventional and...
0
11
0
RT @Ed_Jabbari: Delighted to share our work, out today in @MDJ_Journal ! We highlight alpha-synuclein SAA positivity in PSP and CBS patient….
movementdisorders.onlinelibrary.wiley.com
α-Synuclein seed amplification assay (SAA)-positive results were found in 6 of 59 (10.2%) progressive supranuclear palsy (PSP) and 11 of 37 (29.7%) corticobasal syndrome (CBS) cerebrospinal fluid...
0
9
0
RT @mndresearch: “I am committed to finding effective treatments for MND and FTD.”. @RubikaBalendra won the 2024 #ENCALS Young Investigator….
0
3
0
Delighted that this has been published! I am very grateful to my co-author, faculty advisors, series editor and Elsevier. @Documiev @ElsevierConnect
uk.elsevierhealth.com
Crash Course – your effective every-day study companion PLUS the perfect antidote for exam stress! Save time and be assured you have the essential information you need in one place to excel on your...
0
0
4
Check out our new article on the failure of the C9 ASO trials and lessons learned @AlexCammack @isaacs_adrian.
Our open access opinion in @Brain1878 on the disappointing C9 ASO trials and next steps to deliver an effective treatment for C9ALS/FTD co-written with @AlexCammack @RubikaBalendra @UKDRI @UCLIoN
0
3
13
RT @ratkorad: #ENCALS2024 closed. Tack Sweden! Massive honour being recognised alongside an amazing young investigator @RubikaBalendra. Tha….
0
1
0
RT @smead2: Rubika Balendra and Ratko Radakovic win the ENCALS Young Investigator Award 2024 - ENCALS. Congratulations both. https://t.co/….
0
2
0
RT @isaacs_adrian: Really excited about our latest preprint, where we uncovered a neuroprotective role for neuronal polyunsaturated fatty a….
0
36
0
RT @LSAjournal: C9orf72 poly(PR) binds to 558 RNAs in human cells and the sequence GAAGA is enriched at its binding sites. Poly(PR) has nan….
0
6
0
Our new paper on the RNAs bound by C9orf72 poly(PR)! @isaacs_adrian @adrianisaacslab @ule_lab @ShorterLab @PataniLab @TheCrick. Thank you very much to all involved!.
life-science-alliance.org
An intronic GGGGCC repeat expansion in C9orf72 is a common genetic cause of amyotrophic lateral sclerosis and frontotemporal dementia. The repeats are transcribed in both sense and antisense direct...
2
3
21
RT @isaacs_adrian: Beaten to tweeting our paper by @ShorterLab! Check out the RNAs that bind C9orf72 polyPR -we hope a useful resource for….
life-science-alliance.org
An intronic GGGGCC repeat expansion in C9orf72 is a common genetic cause of amyotrophic lateral sclerosis and frontotemporal dementia. The repeats are transcribed in both sense and antisense direct...
0
8
0
RT @isaacs_adrian: @ShorterLab @LSAjournal And @ShorterLab showed that GAAGAn RNAs increase polyPR phase separation compared to a non-enric….
0
1
0
RT @isaacs_adrian: @ShorterLab @LSAjournal We show that the GAAGA pentamer sequence is enriched at polyPR binding sites .
0
1
0
RT @LSAjournal: This paper by @Isaacs_Adrian @RubikaBalendra et al. identifies transcriptome-wide the RNAs bound by C9orf72 poly(PR).https:….
0
7
0
RT @ShorterLab: Transcriptome-wide RNA binding analysis of C9orf72 poly(PR) dipeptides, delighted for this work with @isaacs_adrian, @Rubik….
life-science-alliance.org
An intronic GGGGCC repeat expansion in C9orf72 is a common genetic cause of amyotrophic lateral sclerosis and frontotemporal dementia. The repeats are transcribed in both sense and antisense direct...
0
11
0