The authors found unusual DNA changes in immune cells of men with Alzheimer's who have lost the Y chromosome. These mutations may help explain how the immune system contributes to the disease, opening new paths to understanding of Alzheimer's. https://t.co/ijvkuK0mb0

A detailed protocol for preparing custom-made cell culture media, offering researchers step-by-step instructions and practical advice for its use in cancer metabolism studies. #cancermetabolism #cellculture https://t.co/WsHsGFhnv1

Have you already read this review? Conserved 3D genome reorganization during DNA repair @compGenomics @uzh_vetsuisse @fenssabanci @vogulcankaya https://t.co/aotuvV4f6x

This is the first demonstration of cell-type specific GPCR localization to primary cilia in vivo in intact brain tissue. @UCSFPsychiatry @EhrlichAliza https://t.co/av6FCj0tKp

TRPM7 and magnesium coordinate the activation and differentiation of human CD4 T-cells. #Immunology #Biology https://t.co/eF3cczzguz

Take a look at this recently published paper in LSA: The unfolded protein response in progeria arteries originates from non-endothelial cell types @Selma_OsMyers https://t.co/8qo9xgBbxz

Our annual collection of exceptional papers in cell biology is here! These articles advance our understanding of the structures and processes at the core of diverse living systems and human disease. https://t.co/9jZQKjQuvk

This review synthesizes findings from genomic, molecular, and disease studies that chromatin organization dynamically shapes diverse DNA repair pathways. @compGenomics @uzh_vetsuisse @fenssabanci @vogulcankaya https://t.co/d6Yy9XNWzG

Our annual collection of exceptional papers in cell biology is here! These articles advance our understanding of the structures and processes at the core of diverse living systems and human disease. https://t.co/XxqU5SJrw2

Li Guan et al., demonstrate that the striatal enriched orphan receptor GPR88 localizes to primary cilia in the striatum but not in the cortex. @UCSFPsychiatry @EhrlichAliza https://t.co/jbrIKEdUy0

The ion channel-kinase TRPM7 maintains intracellular Mg2+ homeostasis, affects early Ca2+ signals, influences downstream Ca2+-dependent signaling pathways and thus is crucial for T-cell activation and differentiation. https://t.co/gGg8l6U4Yj

Progeroid endothelial cells do not show a robust activation of the unfolded protein response, contrary to what has been reported in other arterial cell types such as vascular smooth muscle cells @Selma_OsMyers https://t.co/g5c46AiATb

In our December issue, find out: - How circadian rhythms in immune cells affect responses to cancer treatment. - Links between acetyltransferase expression in the ER and progeria. - Effects of schizophrenia-related genes on neurodevelopment, and much more! https://t.co/zQF9qRlEkI

Researchers have developed a streamlined 2D system that generates mini-oocytes, resembling oocytes, from mouse stem cells. This scalable model offers a new way to explore oocyte characteristics and roles. https://t.co/gTxadbM06d

This study shows that SOX2 is not required for NUT carcinoma initiation or maintenance in vivo, challenging its assumed oncogenic role and refining therapeutic target prioritization. https://t.co/WsuU3HuGaB

Müller cell glutamine processing connects damage to photoreceptors and blood vessels in diabetic eye disease. #DiabeticRetinopathy #EyeHealth https://t.co/JF2ajNu2fc

The authors developed a MALDI-MSI and LC-MS/MS workflow with a scoring algorithm (pepBridge) for confident spatial protein identification in the thymus and identified pathways to aid immune recovery in pediatric cancer patients. https://t.co/m5jpmUSg29

Exciting developments in genomics: Machine learning is aiding researchers in identifying regulators of homologous recombination deficiency through somatic multi-omics data analysis. This could revolutionize cancer therapy and precision medicine. https://t.co/46syW5aOtL

A diverse screening classifies unique categories of plant-based compounds that counteract tau-related disorders. #Tauopathy #NaturalProducts https://t.co/d1IKZwyjCl

A simplified 2D culture system produces oocyte-like mini-oocytes from mouse stem cells, providing a scalable model to study oocyte identity and function. https://t.co/w11vXP9dOO