Jazz Ghataora, PhD
@JazzSynBio
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PDRA in the Tom Ellis Lab @ImperialCollegeLondon exploring environmental synthetic biology things 🧬
South West, England
Joined January 2020
Here are 30 great essays about biology. I consider these to be my "personal canon," and think that they are all basically perfect in their own ways, despite being different in form and style. All have shaped my own writing considerably. I'm not including links here, but you can
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Our new discovery that bacteria utilize extracellular vesicles to deliver RNAs into fungi substantially broadens the paradigm of Cross-Kingdom RNA communication! Big congrats to @J_NinoSanchez, @HuaitongW and all! Thanks for your hard work!
cell.com
In this study, the authors engineer Gram-positive and Gram-negative beneficial bacteria to produce double-stranded RNAs targeting essential genes in important fungal pathogens. It is shown that RNAs...
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"MultiCAST, a streamlined platform for rapid and scalable gRNA-directed transposon insertion in bacteria."
Adapting CRISPR-associated transposons for rapid and high-throughput reverse genetics https://t.co/bKOs6Zl8rv
#biorxiv_micrbio
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Our latest work in @J_A_C_S! Artificial system that can sense, grow, and adapt—just like cells! Our droplets form directional filopodia in response to chemical cues- a step toward life-like materials. #ActiveMatter #SoftMatter #Emulsions #SelfAssembly 🔗 https://t.co/vBBvnwtMYc
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My first review and first publication whilst in the lab of @ProfTomEllis! "Rewiring holobiont systems with synthetic biology" Here we cover core techniques to manipulate holobiont interactions and discuss a potential future for de novo holobiont design https://t.co/s0kYZf9v1H
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SBOL Visual has been a lot of fun contributing to over the past decade. I also think it’s had a real positive benefit in helping improve the readability of genetic designs and am excited to see how the team develops it going forward!
pubs.acs.org
Standards play a crucial role in ensuring consistency, interoperability, and efficiency of communication across various disciplines. In the field of synthetic biology, the Synthetic Biology Open...
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Our latest paper is now out in @MolBioEvol! In this work we show that T:A→G:C mutational hotspots in bacteria are created by short nucleotide sequences (≥8bp), which we call GnT motifs. [ https://t.co/o2mrL9DodZ]. A short 🧵 below:
academic.oup.com
Abstract. Nucleotides across a genome do not mutate at equal frequencies. Instead, specific nucleotide positions can exhibit much higher mutation rates tha
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Rewriting the genetic code with synthetic genomes
nytimes.com
In a giant feat of genetic engineering, scientists have created bacteria that make proteins in a radically different way than all natural species do.
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Online now @ Cell is the yeast multicellular engineering paper from @DrFankangMeng - the fruits of his productive PhD. He developed modular synthetic biology tools to bring multicellular behaviours to yeast - adhesion, juxtacrine signalling and more.
cell.com
By designing synthetic toolkits for contact-based signaling (MARS) and cell-cell adhesion (SATURN), we program yeast to form multicellular structures and perform complex tasks, like building logic...
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New stickers 🧬🩷 I will be giving these out at the Genome Science conference later this week!
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Please RT and share! We have up to two PhD positions available in my group for entry in fall 2026, applications expected in fall 2025. DM me if interested!
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It's 25 yrs to the day since the Human Genome Project & Craig Venter declared joint victory in sequencing the human genome - an ideal time for @wellcometrust to annouce their new project, involving our lab, to begin work towards synthesising human genomes
wellcome.org
Scientists are developing technology to create the first synthetic human chromosome. The ability to write large genomes could transform our understanding of health.
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📢📢 UK researchers in Engineering Biology of all levels (students, technicians, postdocs, PIs, CTOs and CEOs) - what are your thoughts about using AI in your work? The UK government is looking to gather views to shape policy via a survey. If you have 10 min spare please do it.
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Looking for a PhD ? I have a fully funded one for UK nationals on engineering gene circuits in probiotic microbes. Will bring together a lot of existing stands of #synbio research in my group and push towards some exciting applications! Start date will be Sept 2025. Pls RT
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Right, who wants to VOTE for some amazing yeast bioart done by our Synthetic Biology undergrad students in the @ImperialBioeng department? ⬇️
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Joaquin Caro Astorga's SubtiToolKit paper is published today. This cloning toolkit for Bacillus and Geobacillus was years of effort and indepedent work by @JCaroAstorga1, first in my lab and then with @erika_alden_d at the Crick. It's been a journey!
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Wake up babe, a new NGS platform just dropped
A new era in next-generation sequencing has begun with sequencing by expansion (SBX). Learn more and sign up to receive updates: https://t.co/Q04GFBbYXL
#Genomics #NGS #MakeSpaceWithSBX #RocheSBX #AGBTGM
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*ALERT* If you are a bioengineer (or related), if you use synthetic biology for health-related applications, and you wish to start your own lab in a neat place (Naples), in a fantastic research institute, stay tuned, a call will be coming out! DM me if you want to have more info!
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👋 I am a group leader @ Leeds, focused on the study and engineering of translation control in bacteria. Our interests span 🦠 Synthetic biology 🧬 Protein synthesis 🎨 Fluorescence 🧮 Quantitative biology and 📈 Data analysis. Lots going on over the next few weeks, stay tuned!
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