Cortical microglia promote noradrenergic signaling to maintain wakefulness

Bottom line: We may have been measuring the wrong things about sleep. Total hours, REM percentage, deep sleep duration - none predicted brain cleaning as well as norepinephrine pulse frequency did. https://t.co/T5uroaIDIh

FACED 2.0: a method for high-speed, large FOV, volumetric 2-photon voltage and calcium imaging in the mouse and zebrafish brain. https://t.co/tKChXaaC1X

🚀 We’re hiring! Staff Scientist / Postdoc – Tissue Clearing & 3D Image Analysis (m/f/d) (LMU Munich) Are you a great fit, or do you know someone outstanding, please reach out 🔁 If you want to at the frontier of whole-organ / whole-body 3D imaging, and help generate truly

The neural computation of affective internal states in the hypothalamus: A dynamical systems perspective: Neuron

Neuroscientists record two main data modalities: electromagnetic waves and Spiking activities. A longstanding debate in neuroscience is whether the brain waves are essential for understanding how the brain works, or are they merely epiphenomenal. In more scientific terms, do the

Fascinating work! Big kudos Mark and team!🥂

Great commentary by @yulonglilab on our two recent papers introducing red genetically encoded biosensors for calcium and potassium imaging! 🔴 FRCaMPi - Enhanced red calcium sensor 🔴 RGEPOs - First-ever red potassium sensors 📖 https://t.co/6598F2iTr7

Excited to share our new PNAS paper! 🎉 We examined the neural source of rs-fMRI FC using patterned optogenetic manipulation in mice 🧲🧠. A step toward answering a long-standing question. Fantastic work by @HnSk_Moon @hong_seok_jun @CNIR_IBS

It is debated whether poor #blood flow underlies white matter loss in #aging. Our recent study in aged mice supports this idea: Impaired drainage through rare, deep-reaching #venules causes mild #hypoperfusion that triggers inflammation and demyelination. https://t.co/nDVjgZjnWa

Happy to share our recent paper in npj Acoustics🎉📢 We present a pipeline for 3D ultrasound from sparse 2D slices using a motorized 1D array + implicit neural representation. 7.9× faster, 93% accuracy (36 images), 6.3% error in-vivo. https://t.co/Ja7bzd51sb @TelAvivUni @of_sagol

Super excited to share our preprint on cortex-wide dynamics of different layers across leearning, by @yaelesther with collab. Robert Sachdev and @mattlark! Take home message: learning is NOT about the cortical column, it's extra-columnar! Please repost! https://t.co/t0HMWUZg27

New Cellular Source of fMRI Signals 🧲🧠: Activation of somatostatin interneurons induces astrocytic calcium signaling, which drives delayed vasodilation and enhances layer-specific fMRI signals. @CNIR_IBS @NatureComms

https://t.co/CWG3SRH1R1

Cracking the code! 🧠💻 Students in the "#Python for #Neuroscience" course wrapped up an intense 48-hour hackathon, tackling real-world research problems with code - from EEG and AI to proteins and neural networks.

Fantastic work (as always) from Che-Hang Yu and colleagues in Spencer Smith's lab @Labrigger. Neat method to increase scan speed and/or FOV in 2p microscopy. Commercially available from @pacificoptica . I'd love to build this for a client at some point! https://t.co/caj5Pv3ZIA

My lab at @WeizmannScience was completely demolished by the Iranian missile a few days ago. This is hard and sad as nothing was left to save. We study heart regeneration and regenerative medicine. As such, we will regenerate, regrow and rebuild. The one thing that wasn't gone is

Great opportunity for technology savvy students to gain experience in a stimulating & interdisciplinary research environment. Come join us @embl - our group also offers internship projects in advanced microscopy!

🚨New from Urban Lab @OpenfUS in @ImagingNeurosci We combined fUS & Neuropixels in awake mice to test how well fUS reflects neuronal spiking. We targeted 3 visual regions during stimulus-evoked activity. How reliable is fUS vs spikes? https://t.co/WIAUAGOIII

Check out the repo https://t.co/ubLAPwa83G which has all the instruction to get you up and running with NaviGraph. https://t.co/ubLAPwa83G Do not hesitate to reach out if help is needed to set up!