SijbrenOttoLab
@OttoLab
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Systems Chemistry Group at the University of Groningen. Transition of chemistry to biology (incl. origins of life, synthetic life), complex systems.
Groningen, The Netherlands
Joined February 2013
RT @J_A_C_S: Light-Mediated Interconversion between a Foldamer and a Self-Replicator | Journal of the American Chemical Society @LMU_Muench….
pubs.acs.org
Self-replicating molecules and well-defined folded macromolecules are of great significance in the emergence and evolution of life. How they may interconnect and affect each other remains largely...
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RT @J_A_C_S: Simultaneous Formation of a Foldamer and a Self-Replicator by Out-of-Equilibrium Dynamic Covalent Chemistry | JACS @LMU_Muench….
pubs.acs.org
Systems chemistry has emerged as a useful paradigm to access structures and phenomena typically exhibited by living systems, including complex molecular systems such as self-replicators and foldame...
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RT @KaiLiu125348: What can dissipative chemistry bring us? In our recently published paper, we demonstrate the emergence of mechanical func….
nature.com
Nature Chemistry - The use of molecules as fuels to achieve function is largely unexplored. Now it has been shown that fuelled dissipative self-assembly can yield transient droplets that release a...
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RT @CommsChem: Probe the non-enzymatic macrocyclization reaction of benzene-1,3-dithiol in the presence of peptide condensates by reactive….
nature.com
Communications Chemistry - Biomolecular condensates show distinct physicochemical properties that may affect the rate of enzymatic activity and control cellular redox reactions, however, their...
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RT @YannickGeiger1: A little peak into last year's work with @Juntian74804617 and @Armin__Kiani in @OttoLab . You think our replicators are….
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RT @isciverse: This study introduces a new mechanism that decreases error rates and corrects errors in synthetic self-replicating systems d….
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RT @ChemEurJ: Generalist versus Specialist Self-Replicators (Sijbren Otto and co-workers) @seilenfranzli @Nitrogeno_N @GuilleMonrealS @Otto….
chemistry-europe.onlinelibrary.wiley.com
Whether assembly-driven self-replicators that emerge from a mixture of two building blocks specialize on one resource or are generalists was found to depend on their supramolecular organization.
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RT @angew_chem: Binding of Precursors to Replicator Assemblies Can Improve Replication Fidelity and Mediate Error Correction (Sijbren Otto….
onlinelibrary.wiley.com
Binding of precursor molecules to the side of a fibrous assembly of self-replicating macrocycles can improve the fidelity of replication and yield a novel error-correction mechanism, provided that...
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Our newest paper is out!!!.Here we show how a replicator system can correct errors during replication. Congrats @OmerMarkovitch and @Juntian74804617 🥳.Check it out:
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RT @GoldupLab: Fancy doing some shiny new chemistry in a shiny new building? If so, come and join us @UoBChemistry 😀 We have fully funded P….
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Sijbren and Kayleigh were interviewed by @NEMOkennislink at the occasion of the 70th birthday of the famous Miller-Urey experiment. Check it out if you speak Dutch - or know how to use Google translate!.
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RT @pappas_babis: We have a PhD position on phosphate-driven non-equilibrium assemblies @ERC_Research funded at @FitFreiburg @UniFreiburg.….
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RT @OmerMarkovitch: Can a purely chemical system reduces its #errors during #replication? And even "correct" them?. In this latest @ChemRxi….
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RT @leonard_prins: The University of Padova (@UniPadova) has opened the selection procedure for talented students from China that want to p….
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More details about the proposal on the university website👇.
rug.nl
Sijbren Otto awarded an ERC Synergy Grant
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More PhD and also post-doc positions will open - especially prospective post-docs are encouraged to get in touch with Sijbren soon. We offer high-quality research in a multidisciplinary field and (soon) in a brand-new building in Groningen!.
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BREAKING💥Ottogroup was awarded an ERC synergy grant, together with @AshkenasyLab and the groups of Eörs Szathmáry and Andrew Griffiths. Greatest thanks to all collaborators, it was a long and winding journey but it paid off!.
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Please spread the word! We look for excellent students with motivation to work in an interdisciplinary environment. Potential candidates should directly get in touch with Sijbren:
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Reminder 📢 We have a total of three PhS positions open! Two within a MSCA ITN, more at Applicants should have been no longer than 12 months in NL ober the last 3 years; deadline 31 oct. One more position on diff. funding is without residence constraints.
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Some really exciting news in ooL-studies: there's maybe a good reason why that lengthy and bulky molecule ATP became our universal energy carrier. ADP catalyses its own phosphorylation, and that of other NDPs! Congrats to all authors at @MoranLabChem.
Happy to share that @EmilieWerner7 and I's paper on nonenzymatic phosphorylation is now out! I'm so proud of the work we've done💪.Glad I got to work on this in @MoranLabChem 's lab, and collaborating with the likes of @RJ_Mayer has been a pleasure!.
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