Ed Needham
@NeedhamNeuro
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Neurologist treating and researching neuroimmunology & neurocritical care; worser-half of @drzoeneedham
Cambridge, England
Joined July 2014
RT @Brain1878: Othman et al. studied the impact of apomorphine and methylphenidate on consciousness biomarkers and clinical arousal in ICU….
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RT @MedCambridge: Passionate about neuroimaging and data science?. Join the @TBI_REPORTER as a Postdoctoral Research Associate in Image Ana….
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RT @Mayo_AING: Beware commercial tissue based assays (TBAs) to detect cell surface autoantibodies in neurology. TBAs are often used as scr….
pubmed.ncbi.nlm.nih.gov
The diagnostic performance of EUROIMMUN IIF-TBA in detecting NSAbs in autoimmune encephalitis is suboptimal. NMDAR antibodies, among the most common NSAbs, can be missed in 50% of cases. This...
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RT @CellCellPress: and how dysfunctional meningeal lymphatics regulate synaptic physiology in a microglia-dependent manner..
cell.com
Dysfunctional meningeal lymphatics interfere with the inhibitory synaptic inputs and disrupt excitatory/inhibitory balance on cortical neurons in a microglia-IL-6-dependent manner. Enhancing the...
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RT @NeurologyCP: Implementation of 2HELPS2B Seizure Risk Score: A Cost-Effective Approach to Seizure Detection in the Intensive Care Units….
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RT @Mayo_AING: #CASPR2-#antibody diseases are provide clues to mechanisms of autoantigen-specific tolerance . Here - in @ScienceAdvances -….
science.org
Central and peripheral tolerance thresholds that license CASPR2-antibody diseases are identified.
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RT @LukensJohnR: Microglia dysfunction, neurovascular inflammation and focal neuropathologies are linked to IL-1- and IL-6-related system….
nature.com
Nature Neuroscience - The authors show that brain inflammation in COVID-19 correlates with viral load, systemic inflammation and virus-sensing pattern recognition receptors. Microglial dysfunction...
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RT @tccambs: A huge privilege to participate in the @ARUKscientist debate, discussing hope for future treatments for devastating dementias….
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RT @EnriqueZenitram: About half of patients with NPH and parkinsonism have an abnormal DaT SPECT, but they do not have nigrosomal loss like….
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RT @MedCambridge: 🚨We're #hiring🚨. Postdoctoral researcher to work with @Menon_Cambridge in data collation and curation from patient sample….
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RT @AppavuBrian: Congrats to @shragrawal and her team in Cambridge and across the UK, including @smithclaudiaann a….
thelancet.com
With STARSHIP, we validate the outcome association of CA derangements as assessed by PRx in pTBI in the first prospective observational multicentre study. This provides additional evidence for the...
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RT @EliaSechi: Seasonal variation in myasthenia gravis incidence - Journal of Neuroimmunology @neurotutto @PietroZa….
jni-journal.com
Environmental factors may contribute to myasthenia gravis (MG) development, sometimes with seasonal patterns of exposure. However, whether seasonality has an impact on MG incidence remains unclear....
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RT @Cunningham_Colm: We are looking for a talented and motivated post-doc to work on new brain injury arising from systemic inflammation. C….
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RT @francisco_alobo: This is one of the most comprehensive reviews of EEG monitoring during anesthesia and critica….
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RT @BaiardoMartina: A comprehensive review on sepsis published today @NEJM . 🌍With 48.9 million of cases and 11 million it’s a global healt….
nejm.org
Sepsis is a life-threatening, heterogeneous disorder involving a dysregulated immune response to infection. Research to identify subtypes and targeted therapies for host dysregulation is ongoing.
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