Nanditha Rajamani
@NaN_Value
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Doctoral student at the Network Stimulation Laboratory, Charité Universitätmedizin. Interested in Deep Brain Stimulation & Neuroimaging.
Boston, MA
Joined January 2021
Modulating networks using DBS is an effective treatment for PD – but which circuits map to improvements in individual symptoms such as tremor, bradykinesia, rigidity, and axial? A 🧵 about our new paper out now in @NatureComms @netstim_org
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As per usual, the stim brains line up is beyond exciting!! 🫡Looking forward to it!!.
Curious about how to get a job in academia? 👩🎓or the latest in neuromodulation for epilepsy? ⚡️🧠.Join us on 21st Nov at 12 PM ET/ 6 PM CET to learn more!.Ft. Robert Fisher and our very own @fredschaper_.Register here to attend:
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Congratulations!! well deserved and can't wait to see you here!.
Congratulations to @b_hollunder for getting a Thiemann Fellowship to join @foxmdphd at the @Brain_Circuits next year! Couldn’t be more proud and this is so well deserved after a truly fantastic PhD! 🙌👏🎉🎉🥳🎈🎁
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Really looking forward to this!!.
🎙️ Just 2 days to go! Join us for an insightful talk from @ArynGittis and @drpouratian. Don’t miss the chance to dive deep into the latest and greatest in optogenetics and pallidal burst stimulation. 📅 October 31st 🕒 12 PM ET/5 PM CET 🖥️ Register now 👉
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RT @stimbrains: 🚨 The talk series is back from its summer break 🚨.Join us on Thursday, October 31st 12 PM ET/ 5 PM CET for a discussion o….
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RT @EMiddlebrooksMD: Taking the art of Dr. Rhoton to the next level of 3D using photogrammetry of dissections for DBS targets! The full atl….
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Congratulations Bahne & team!! ⚡️🧠.
🚨🥁Preprint alert: #DBS Programming is currently a tedious trial and error process that involves testing many settings – each time asking the patient to perform motor tasks to see how things improve. Could we use DBS-#evokedpotentials to guide programming?
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RT @bahnebahners: 🚨🥁Preprint alert: #DBS Programming is currently a tedious trial and error process that involves testing many settings – e….
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Fantastic paper and nice tweetorial - good evidence to show that early-stage DBS might slow motor symptom progression! Read this fantastic work from @MalloryHacker et al. Thank you for including me!!.
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RT @andreashorn_: I am super excited by this figure just published by @MalloryHacker et al. – why?. Let’s unpack… 🧵. .
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Thanks for the great opportunity @GreenJournal podcast and @DrJeffRatliff! Please tune in to listen about our recent work! 🎧🎙️.
Excited to discuss @NaN_Value’s recent @NatureComms paper on DBS for Symptom-Specific Networks in Parkinson Disease on the @GreenJournal podcast – thanks @DrJeffRatliff for the kind interview and fantastic questions!. 🎧🎧 Episode available here:
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RT @shansiddiqi: Out @NatureNeuro: Network localization of brain stim targets for PTSD. TLDR: Lesions connected to this circuit REDUCE ris….
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RT @foxmdphd: Can we use DBS evoked potentials to guide programming? @bahnebahners presenting @DBSThinkTank suggests we’re getting close!….
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RT @andreashorn_: Thank you for the kind editorial @garance_meyer & @DrPhilipMosley on our blinded replication study with @SameerShethMD @R….
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RT @andreashorn_: Excited about a collaboration out at @CommsBio with the stroke team at @ChariteBerlin – @IdaRangus, @sofiari91 & @anna_ku….
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RT @MassGeneralMDs: A study co-authored by #MassGeneral physician @andreashorn_ MD was covered by @ScienceDaily. The study developed a deep….
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26/n As a side note but also very importantly! our reviewer comments along with several validation results lead to supplementary material with 36 figures! Oof! Special thanks to @HelenFriedrich_ @c_neudorfer and the twitterless Konstantin Butenko for making this possible.
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25/n We presented and validated across 3 cohorts, a symptom-response tract library for four cardinal symptoms of PD— tremor, bradykinesia, rigidity and axial symptoms. Finally, we developed and tested an algorithm capable of optimizing symptom profiles in patients with STN-DBS.
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24/n Sounds promising! In the future, algorithms such as Cleartune could reduce patient burden and harness the potential of advanced 16-contact electrodes or multiple independent current control technology, to finely steer current and modulate different symptoms differently.
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23/n We tested Cleartune in a clinical setting with 5 patients prospectively enrolled by @MartinMReich1 from the University of Würzburg 🙏. In this blinded feasibility study: for 4/5 patients, Cleartune settings led to comparable, if not better, improvements than SoC!
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