Provocative @BloodPortfolio 🇬🇧 Myeloma-XI trial analysis! Raison d'être of HR #MMsm criteria is to 🔎 early relapse. 2025 IMS/IMWG criteria better, but can GEP go the final mile to identify functional HR MM? Evidently, yes! Only 2/135 truly unexpected FHRMM when both used.

Analysis of patients with NDMM on the Myeloma XI study demonstrates comprehensive genetic assessment incorporating GEP in addition to IMWG/IMS HR definition improved identification of patients with early progression (<18m) @MyMKaiser https://t.co/jsUUWjqdVq

In 2022, Nadhim Zahawi’s solicitor sent me a libel threat - and said I wasn’t even allowed to say he’d written to me. The Solicitors Disciplinary Tribunal ruled that was improper. Now he’s appealing. A 🧵 on why it matters.

🔔BREAKING NEWS! #ESHMM2025: VIDEOS & PRESENTATIONS NOW AVAILABLE FOR FREE ON #ESHELEARNING Enjoy viewing ➡ https://t.co/pL2BcyWg9q 5th How to Diagnose & Treat MULTIPLE MYELOMA Chairs: @H_Einsele Maria Theresa Krauth @mvmateos @OmarNadeemMD #ESHCONFERENCES #ESHELEARNING #MMsm

📣 CALL FOR ABSTRACTS FOR #ESHMM2026! Present your work at the 8th Translational Research Conference on Multiple Myeloma ➡️ https://t.co/zITdtTOZdh 🗓 March 26-28, 2026 / Stockholm, Sweden 🇸🇪 Chairs: Hartmut Goldschmidt, @MyMKaiser, @SLentzsch #ESHCONFERENCES #Haematology #MMsm

Looking forward to speaking on treatment of High-risk #myeloma at @EHA_Hematology conference in Milano in June - many thanks @Myeloma_Society and EHA for invite. In the meantime, hope people might enjoy our @BritSocHaem podcast on this topic: https://t.co/wabqo5CZzP

REGISTRATION IS OPEN FOR #ESHMM2026 March 26-28, 2026 / Stockholm, Sweden 8th Translational Research Conference Multiple Myeloma Chairs : Hartmut Goldschmidt, @MyMKaiser, @SLentzsch To register & for more information 👉 https://t.co/zITdtTOZdh #ESHCONFERENCES #MMsm #HAEMATOLOGY

Even with increasingly intensive therapy regimens, high-risk patients perform worse. There is a high demand for precision diagnostics to determine the individual benefit. Martin Kaiser gave a talk on the aspects to take into account at this year's #ESHMM2025 #ESHCONFERENCES #MMsm

Our Team is ready to welcome you in Vienna for the 5th How to Diagnose and Treat Multiple Myeloma! Registration opens at 7:30 am CEST! ➡ https://t.co/f4QsVEBgqA Chairs: @H_Einsele, Maria Krauth, @mvmateos, @OmarNadeemMD #ESHCONFERENCES #MMsm #ESHMM2025 #HAEMATOLOGY #HEMATOLOGY

Attend on-site or virtually! Confirmed speakers include @IdoAmitLab @NBahlis @FrancescoMaura4 @BrunoPaiva_UNAV @szusmani @myelomaMD @MyMKaiser @SagarLonialMD @TCupedo @Leif_Bergsagel @DrGarethMorgan1 @MarkBustoros and many more!!

A fantastic collaborative effort, very grateful to all,( @RaabMarc @mvmateos @BrunoPaiva_UNAV @HDMyeloma on this platform) and many other coauthors, their study groups and teams and, most of all, patients! #mmsm

Prognostic association of 2+ HRCAs with poorer outcome was stronger for trials performed after 2015, suggesting marked progress for standard risk, less so for high-risk patients. Fortunately, very recent GMMG-CONCEPT and OPTIMUM/MUKnine trials have informed better approaches.

The results were highly consistent, which is striking, given the vastly heterogeneous treatments and patient populations. Without a need for complex data transfers, scientists around the globe were empowered to interrogate their own data and explore new aspects across trials.

This work took a #federatedanalysis approach, letting all participating collaborators investigate themselves trial-by-trial how consistent co-occurrence of 2+ HRCAs is for predicting high-risk #myeloma , using a centrally pre-defined free algorithm that was shared with everyone.

Very happy to see our global collaborative effort published in @JCO_ASCO : co-occurrence of ≥2 HRCAs is consistently associated with highest unmet need in NDMM and RRMM, across time and treatment modalities.

A global relationship recession: across the world, the drop in fertility is not due to less children per couple, but to a significant drop in the number of people in relationships. Outstanding data story by @jburnmurdoch @ft

We had family over from the UK, and some of them tried Spätzle for the first time. Naturally they loved it. As a leaving gift, I gave them a Spätzlehobel. They seemed confused. After staring at it for a few minutes, one of them said "Erm, cool...thanks for the cheese grater".

Nice @ESHaematology - instead of removing access in time for the New Year, access is made free for all - have a look if you are interested in #myeloma (😉 @ASH_hematology - inspirational?)

Fantastic evening ⁦@StPaulsLondon⁩ hosted by ⁦@bloodcancer_uk⁩ ⁦@BloodCancer_Res⁩ c2000 people. Amazing carol concert & speakers. ⁦@campbellclaret⁩ #siennamiller #timothyspall et al ⁦@rowntron⁩ @rubina1402 ⁦@AdeleKFielding⁩ ⁦@MyMKaiser⁩

📣 #ESHMM2025 MEET THE CONFIRMED SPEAKERS TO DATE! Register & submit your abstract here ➡ https://t.co/f4QsVEBOg8 5th How to Diagnose & Treat MULTIPLE #MYELOMA 🗓️ April 3-5, 2025 in Vienna 🇦🇹 Chairs: @H_Einsele, Maria Krauth, @mvmateos, @OmarNadeemMD #ESHCONFERENCES #MMsm