Over the past years we studied the cycloisomerization of 1-bromoalkynes under gold(I) catalysis, showing that unactivated C–H bonds at the 5-position can be functionalized without directing groups, via a vinyl cation-type transition state and 5-endo-dig reactivity.

Honored to welcome such a stellar group of speakers to #BarluengaConference2025! Thanks to all who make this event exceptional every year

Excited to share our latest publication in Organic Letters @JOC_OL! Learn how to prepare 3,4-Dihydropyrimidin-4-ones from Dihydrooxadiazoles and Fischer Carbenes by a (3+3)-cycloaddition. https://t.co/ISj1Ci7xB0 Congrats to first author @ssanchez1005 and to all the authors!!!

Very happy to share our homoallylation reagents @J_A_C_S . Extremely proud of the work of @BLozanoFabuel and Javi Teresa…a long journey in which they’ve grown up as scientists 😊. Thank you @isra_group, always a pleasure to collaborate with you!

Post-transition State Bifurcations in Reactions That Form Pimarenyl Cation Diastereomers─Implications for Terpene Biosynthesis https://t.co/Xi5MjM00z3

Amazing talk by Prof. Luis Ángel López!!👏🏻👏🏻 Very interesting chemistry. Hope you have enjoyed as much as us 🙌🏻🔝

Another amazing paper by Prof. Tuoping Luo! Check out this beautiful gold-catalyzed cascade reaction that the Luo lab developed for the synthesis of 7-epi-Erogorgiaene! What is the mechanism of the reaction?

#TotalSynthesis of Annotinolide B via Sequential Quinoline Dearomatization by Bhawyanth Duvvuru and Myles W. Smith at @utswnews in @J_A_C_S https://t.co/BcQuAmVsYL

An interesting skeletal construction method published in Nature: https://t.co/kAONxZCLuJ A similar approach, published 75 years ago, still seems to be more convenient (although may be less tolerant): https://t.co/k99izEUoU7

If you are interested in carbene chemistry, you can't miss Prof. Luis Ángel López García's talk 🗓️ Thursday 23th October 🕓 16:00 📍 Sala de Conferencias QUIFIMA @iucinquima @fcienciasuva @UVa_es

🚨 Check out the latest chapter of Comprehensive Organic Synthesis (3rd ed.) — a deep dive into allyl borons! 🤠 #OrganicChemistry #Synthesis. https://t.co/wDA9mcReab

https://t.co/hpYMlJWMPC https://t.co/ikBVRRcQP8 https://t.co/gitg3grA0z

Honored to see two of our recent @JOC_OL publications among the most read this month!! Check them out in the following post(I also leave the link of our third OL this month, which will appear back-to-back with the second one). Thanks to the readers of @JOC_OL for the interest

At PbLab we are moving toward more complex systems, studying new variables to unlock regioselective reactivity. Collaborations with leading groups will broaden the impact of our work. Stay tuned! 👀

Extending this study to terpene-derived trisubstituted systems, we discovered a new reaction pathway: a 5-exo-dig process on unactivated C–H bonds, not previously observed in this context. https://t.co/NSDCFGKeRj

We are excited to share our two back-to-back papers in @JOC_OL! 🚀 We studied how conformations affect the cycloisomerization of 1-bromoalkynes, highlighting the key role of a methyl group on the cyclohexane ring.

a-F-amines are unstable. Not in Ukraine!

Today, we disclose a general scalable approach to azabicycles and 1,2-BCPs! In @angew_chem: https://t.co/JJnrkKWLLM

🎉Our new scientific contribution is out now!!🎉Herein we present an overview of how the conformational effects affect the outcome of our gold(I)-catalyzed cycloisomerizarion of 1-Bromoalkynes. (1/3) https://t.co/YHb0LkbxSX

This 5-exo-dig transformation shows some really interesting features which are currently being studied at @PbLabUniOvi. We are so excited to share our work with the community. Please, stay tuned to find out more about these powerful transformations!!!✨(3/4)

✨I'm also very happy to announce that the second part of our study is out now in @JOC_OL!!✨ Herein we present an overview of how conformational effects influence the outcome of our gold(I)-catalyzed cycloisomerization of 1-Bromoalkynes. (1/4)