Check out our MS describing the in vivo cycle of chaperonin TRiC/CCT, in a wonderful collaboration with Martin Beck's lab: https://t.co/0d2O9smiMF 1) The study established TRiC's important function in folding newly translated proteins and defines its ATP-driven cycle

Sure smells like a scenario for septins, wouldn’t you say @SeptinLab @ewers_helge ?

My lab at UCSF ( https://t.co/UMmzM70Hgw) is looking to recruit multiple postdocs across the spectrum of wet/dry lab interests to contribute to our research in synthetic gene regulation, combinatorial genetics, and tissue biology (including liver biology and immuno-oncology). We

MBoC Call for Papers on Evolutionary #CellBiology. Submit an article by Dec 30 to lead editors: @Dey_Gautam, @EMBL @McMurraylab, @CUAnschutz @mcmomany, @universityofga @onishilab, @DukeU @C_M_Schroeder, @UTSWNews @HVGoodson, @NotreDame Submit: https://t.co/6ql92q1dxc

Sadly, your email does NOT find me "impelled by a fervent scientific curiosity in the field of Plant Biology" hence I'm afraid I will not "avail this opportunity to share [my] scientific excellences" but I salute your farraginous lexicon 😄😄 (no disrespect to plant biologists)

Ok, a second paper accepted in the same week is helping a bit, I must admit 😐

News that our paper was accepted today somehow doesn't bring the same sense of satisfaction or joy...

A trove of insights! I found an ArgPro dicodon exactly where we’d predict to drive pausing in Cdc12, the septin we think is slowly translated, in a loop where the α2 helix would be exiting the ribosome & closing the α-β sandwich where other Frydman lab data showed chaperones bind

🚨 Great alternatives to BioRender are now available!! 📢 @NIAIDNews offers a collection of public figures and icons for everyone to use. Check it out at https://t.co/cZFQAf5nTz

1. Check out our MS just out! Amazing Mauricio Aguilar developed a new ML pipeline that identifies ribosome pausing sites as an Anomaly Detection problem to overcome spurious signals that arise when analyzing RiboSeq data.

Register here: https://t.co/XO3RCcrEpN for the 13-16 April 2025 Lisbon. Please join us!

I was an ableist asshole when I first became a teacher. Because that’s what I was taught! In my defense, academic institutions told me a strict attendance policy was required. What changed my perspective & my assessment criteria? Disabled students 🧵

MBoC Call for Papers on Evolutionary #CellBiology. Submit an article by Dec 30 to lead editors: @Dey_Gautam, @EMBL @McMurraylab, @CUAnschutz @mcmomany, @universityofga @onishilab, @DukeU @C_M_Schroeder, @UTSWNews @HVGoodson, @NotreDame Submit: https://t.co/6ql92q1dxc

Yay, #SEPTforSEPTINS is here again!

I was reminded that most proteasomes reside in the nucleus and I was like, "How did I forget that?" and then I was like, "Because it's basically never shown in any figure about the proteasome"! Are cytoplasmic proteasome substrates imported into the nucleus for degradation? 🧐

Just submitted my 26th manuscript peer review of 2024. That's one every <10 days. I think I am going to take a little break now...

McMurray lab and @CSD_CUAMC graduate/alumnus making us all very proud 👇🏽👇🏽👇🏽

Ouch.

Beautiful work! fits so nicely with our 2022 study of a yeast septin protein that appears to stall during heterologous E. coli translation when GroEL is missing (PMID 35947497)