Matthew Watt
@MattWattUnimelb
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Researcher in metabolism, NAFLD and type 2 diabetes at the University of Melbourne. Associate Dean Research, Faculty of Medicine Dentistry & Health Sciences
Joined November 2018
See new job opportunity in our lab. •Collaborate with world-leading industry partner.•Join a dynamic team advancing metabolic disease research and shaping the future of obesity treatments.
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Incredibly proud of this work. We detail the evolution of liver-secreted and plasma proteins with MASLD progression, providing a rich resource defining human hepatokines and a predictive model that stratifies MASH. @will_denardo @UniMelbMDHS
cell.com
De Nardo et al. profile the plasma and liver-secreted proteome from obese individuals spanning the spectrum of MASLD. They identify biomarkers for MASH in persons with obesity and develop and...
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Pleased to share our recent work showing the protein HEXA improves #muscle insulin sensitivity in mice with type 2 #diabetes. Superbly led by Magda Montgomery @UniMelbMDHS .
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AFL football alive and well with FIVE teams training at Lysterfield Junior Football Club. Keep those kids active!
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Pleased to share our newest paper describing a new mechanism for fatty acid transfer between lipid droplets and mitochondria, which is important for regulating fatty acid oxidation. A wonderful team effort and work that I’m extremely proud of.
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Pleased to share our new review with @DrGregSteinberg outlining the role of the gut-adipose tissue-liver axis in MASLD. Integrative Metabolism in MASLD and MASH: Pathophysiology and Emerging.
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Great post doc opportunity in Melbourne.
🚨 Join Our Team! 🚨.We’re on the hunt for a brilliant postdoctoral researcher with a passion for neuroscience or metabolic disease. This is your chance to work at the intersection of academia & industry, driving innovation in obesity & T2D research. 🌟.
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Interesting read. Metabolic dysfunction-associated steatotic liver disease: heterogeneous pathomechanisms and effectiveness of metabolism-based treatment - The Lancet Diabetes & Endocrinology
thelancet.com
The global epidemic of metabolic dysfunction-associated steatotic liver disease (MASLD) is increasing worldwide. People with MASLD can progress to cirrhosis and hepatocellular carcinoma and are at...
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Thrilled that the metabolism theme in Dept of Anatomy & Physiology were awarded NHMRC and ARC grants in #obesity #MASLD, #fibrosis and #aging. Go @garrondodd @Ben_Leo_Parker @MagdaMontg64866 @MattWattUnimelb 🎉💯🙂 @UniMelbMDHS
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It was a pleasure to be part of the graduation ceremony for our Bachelor of Biomedicine students. All the more special because my niece was one of our newest graduates!.@UniMelbMDHS
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Thrilled to share our latest work using Lipidome profiling in advanced metabolic liver disease which identified phosphatidylserine synthase 1 as a regulator of hepatic lipoprotein metabolism: Cell Reports #MASH #liver @UniMelbMDHS.
cell.com
Anari et al. show that hepatic accumulation of phosphatidylserine (PS) is associated with hypertriglyceridemia in metabolic dysfunction-associated steatohepatitis (MASH). Increasing expression of PS...
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Just spent two days at the Department of Anatomy and Physiology retreat. Inspired by the collegiality, openness and our future together. @UniMelbMDHS #nogolf!
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Department of Anatomy and Physiology Research Day- kicked off with new tech session and now the ECRs are giving a 1 min teaser of their posters. Innovation and enthusiasm!! @UniMelbMDHS
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New work showing lipolysis is essential for brown adipose thermogenesis (requires deletion of both ATGL and HSL).
The research led by Prof. @Dominique Langin and Dr. @EMouiselsheds light on the importance of fat degradation in brown fat to generate heat. Exciting findings published in @Cell_Metabolism. @I2mcT @CHUdeToulouse @UT3PaulSabatier @Inserm 1/5.
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Our pleasure to host @jimmytrevaskis from Eli Lilly at the Department of Anatomy and Physiology at @UniMelbMDHS. Here sharing his experience in pharma with our early career fellows #obesity #therapy
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Some important reminders for those presenting their metabolomics data. | The EMBO Journal
embopress.org
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RT @NoureddinMD: Breaking news. Sema hits both points for MASH resolution and Fibrosis improvement in the Ph 3 study! 62.9% vs 34.1% and 37….
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Kit Ng presenting his final PhD oration on exercise phosphoproteomics and skeletal muscle at Dept of Anatomy and Physiology. Awesome to see the journey. @BenParkerLab @UniMelbMDHS
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New method to automate the interpretation of isotope tracing data for assessing metabolic flux- look useful but any consideration of assessing lipid flux?.
Our study now @NatMetabolism. Analysis and expansion of machine learning approaches to automate the interpretation of isotope tracing data for assessing metabolic flux. Congrats Shiyu 🎉.
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