Thrilled to start 1/2026 as Chief of CV Medicine and Co-Director of the CV Institute @IUMedSchool / @IU_Health! Grateful for lifelong friends, colleagues, trainees @ NUFSM & continuing collabs. Excited for what's to come at IUSM/IUH! @IUSMDeptMed @saraj_pereira @IUCVInstitute

How to develop good research questions https://t.co/XIjlYux0hC #MedEd #MedX #Science #phdlife #PHD #AcademicTwitter #academicWriting

A new study by @SusanQuaggin, @hmaekawa0520 and colleagues in @jclinicalinvest revealed SGLT2 inhibition protects kidney function by SAM-dependent #epigenetic repression of inflammatory genes under metabolic stress https://t.co/QmptmoqXsY

PSA: Stop calling macrophages in tissue M1 or M2. These are not states that exist in biology. The only use of M1 is a macrophage cultured ex vivo with LPS and IFNg; and for M2: IL-4/13/10. Macrophages in tissues are highly complex and diverse and do not resemble either of the

For our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper? You got it: https://t.co/lfhJyTUXKg

A very useful resource, e.g. for cell annotation in future work or for deconvolution of bulk RNAseq data 🔗link to paper: https://t.co/RvqTcQNX3Z 📊atlas data: https://t.co/9y94ICXZyX 🌐interactive WebUI: https://t.co/XMLIvtRN0J

A very comprehensive effort to develop a single-cell atlas of human atherosclerosis based on 79 plaque samples from 3 vascular beds and >250K cells👇

Resistin-like molecule γ attacks cardiomyocyte membranes and promotes ventricular tachycardia | Science

New preprint alert: https://t.co/RugxCYzlSH. Excited to share our analysis on the impact of genetic variants on single-cell chromatin accessibility in blood, using scATAC-seq and WGS from over 1,000 donors and 3.5M nuclei as part of TenK10K phase 1 🧬 🧵👇 (1/n)

Northwestern Medicine scientists have discovered how a subset of #ImmuneCells are essential for successful #OrganTransplantation acceptance, per @jclinicalinvest.

Suppression of Cardiac Allograft Vasculopathy by a Macrophage Efferocytosis Receptor - ScienceDirect

Honored to be @ASIPath President. @umiamimedicine @univmiami @SylvesterCancer @UMiamiPathology Become a member 👇#pathobiology

Scientists ⁦@NorthwesternMed⁩ have discovered how targeting a subset of immune cells may improve organ transplantation acceptance and long-term survival, per a study in ⁦@jclinicalinvest⁩ ⁦@SchrothSam⁩ ⁦@NU_Pathology⁩ ⁦⁦

This was so much fun to write, thank you @SwirskiLab and @FGinhoux !! A summary of the many surprising jobs that immune cells do after hours (and it is more than just cleaning up) Immune system influence on physiology | Science

Exciting news! The Alcaide lab officially relocated @umiamimedicine @univmiami @SylvesterCancer & is ready to thrive in this vibrant collaborative environment!#cardioimmunology positions available. DM & Stay tuned. Thx @tuftsmedschool @tuftsuniversity for an incredible journey.

Led by @andrewhakeem, we reviewed the emerging evidence of organ crosstalk between the liver and heart during cardiometabolic disease. Key mechanisms include inflammation, liver-derived secretory factors, bone marrow reprogramming, and CHIP. @JACCJournals https://t.co/xOPkNcX6hW

New online! CD40–CD40L: a milestone in the recognition of atherosclerosis as an immune disease

Galán et al found that #cDC1s are proatherogenic via local #immunity & developed a novel #immunotherapy for #atherosclerosis based on cDC1-targeted lipid #nanoparticles. Learn more at https://t.co/zcgacYfTS7 @Sancholab @SBiomagMfb @aramiro_ramiro @CarregalSusana

reprogramming cells with transcription factors is our most expressive tool for engineering cell state traditionally, we found TFs by ~guesswork @icmlconf we're sharing @newlimit's SOTA AI models that can design reprogramming payloads by building on molecular foundation models

💥 A gut microbe metabolite that drives #atherosclerosis? Yes—Imidazole propionate (ImP) triggers vascular inflammation without changing cholesterol. 🧪 We show the pathway—and how to block it. https://t.co/ZazBw50FFC #OpenAccess at @Nature @CNIC_CARDIO #microbiome #CVD