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Mathieu Lupien Profile
Mathieu Lupien

@MatLupien

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Senior scientist @Princess Margaret Cancer Centre, Prof @ UofT. BHAG: Conquer cancer by treating it as a disease of the chromatin. Also on Bluesky

Toronto, 🇨🇦
Joined July 2010
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@MatLupien
Mathieu Lupien
2 months
A jewel of a presentation on the history of chromatin. Always a pleasure to go back in time with those who helped shape it. I am grateful for the insights and stories shared by Drs. Ada and Donald Olins. https://t.co/d92wjrljRs
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@MatLupien
Mathieu Lupien
2 months
Less than a month to go until the GRC on Hormone-Dependent Cancers! Looking forward to reconnecting with the community and sharing our latest on epigenomics of ecDNAs in tumor evolution. Hope to see you then.
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@MatLupien
Mathieu Lupien
2 months
Less than a month to go until the GRC on Hormone-Dependent Cancers! Looking forward to reconnecting with the community and sharing our latest on epigenomics of ecDNAs in tumor evolution. Hope to see you then.
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@Fusion_Conf
Fusion Conferences
3 months
@MatLupien we are looking forward to your presentation at #EREHD25 in Mexico this November🧬 Please share with your followers to let them know our early bird & talk submission deadline has been extended, so submit & register today! 🔗 https://t.co/kAMjifcs5t
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@Fusion_Conf
Fusion Conferences
2 months
Are you currently in the ERE related field and want to find new collaborative opportunities? Join our Chairs @ChiappinelliLab, @shenhui1986, @twang5 & @paultaowu at the upcoming Endogenous Retrotransposable Elements & Human Diseases Conference this November! #EREHD25 🎙️Talk
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@MatLupien
Mathieu Lupien
2 months
If you're into super-resolution microscopy, check out the new study from Myles Brown's lab showing dynamic, ligand-dependent changes in H3K27ac structure with implications for endocrine resistance.
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biorxiv.org
Changes in gene expression regulated by ligand-dependent transcription factors such as estrogen receptor-α (ERα) involves the recruitment of coactivators including p300 that acetylates histone H3 at...
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@Yael_David__
Yael David
3 months
🚨 New meeting this fall in Brussels! 🚨 Cutting-edge science, amazing colleagues, & a RARE career development workshop for trainees-covering pharma, consulting, writing, start-ups & more 🤩 #epigenetics2025 Registration is open!! @epicypher @FuksLab https://t.co/SYynz5fyxi
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@MatLupien
Mathieu Lupien
9 months
Big news! Recursion is a sponsor for the 2025 Cancer Genetics and Epigenetics GRC! With Recursion ( https://t.co/TRKJqyWAHF​), this GRC conference is one where advanced technologies and human ingenuity will converge to outsmart cancer’s complexity. Join us
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recursion.com
Dive into Recursion's innovative approach to decoding biology. Join our mission & explore what AI drug discovery companies can do. Contact us today!
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@PMResearch_UHN
Princess Margaret Cancer Centre Research
10 months
🌟What is epigenetics and why is it crucial for cancer research? Meet Dr. @MatLupien at @UHN @pmcancercentre, newly elected Fellow of the Royal Society of Canada. His work in cancer epigenetics is transforming how we can treat breast and prostate cancer: https://t.co/JyqUOKxZAl
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@MatLupien
Mathieu Lupien
10 months
Epigenome Technologies Inc. is our latest partner of choice for the 2025 Cancer Genetics & Epigenetics GRC! 🔍 Discover their cutting-edge single-cell histone and transcription factor profiling technologies:
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@MatLupien
Mathieu Lupien
11 months
Join our mission! Donate here to support innovation in cancer genetics. https://t.co/rkIQ04tps9 Stay tuned as we decode the mysteries of cancer!
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@MatLupien
Mathieu Lupien
11 months
Thanks to our sponsors: @biomodalhq , @ZymoResearch , @NEBiolabs , T-ONE, @AtlasXomics , @OlinkProteomics , @GeneseeqInc , and @activemotif . Their support is vital in tackling cancer research challenges.
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@MatLupien
Mathieu Lupien
11 months
🔍 What Secrets Lie Within Cancer Genetics? Scientists are racing to uncover clues in our genomes for new cancer treatments. The answers await at the 2025 Cancer Genetics and Epigenetics @GordonConf! https://t.co/8gG4NFQgkN
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@NatureRevCancer
Nature Reviews Cancer
11 months
#singlecell epigenomic technologies are redefining our understanding of cancer evolution. Now, @MartheLaisne, @MatLupien & @VallotCeline explain how epigenomic heterogeneity drives tumor cell state diversity through reprogramming and selection. https://t.co/FFwWAtUQxz
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@MatLupien
Mathieu Lupien
11 months
📖 New review in Nature Reviews Cancer on how epigenomic heterogeneity drives tumour evolution! We dive into: Check it out if you're into epigenetics, single-cell tech, or the future of cancer therapy! 📖 https://t.co/WqJtxv1dH9
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nature.com
Nature Reviews Cancer - Single-cell epigenomic technologies are refining our understanding of cancer evolution. Here Laisné et al. describe how epigenomic heterogeneity generates dynamic...
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@VallotCeline
Céline Vallot
11 months
📝Epigenomic heterogeneity as a source of tumour evolution Just out in Nature Reviews Cancer - a piece we wrote with @MatLupien and @MartheLaisne, a fantastic team work and such a pleasure to exchange & confront ideas on cancer epigenetics. 👉 https://t.co/3ChmgZqHTU
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nature.com
Nature Reviews Cancer - Single-cell epigenomic technologies are refining our understanding of cancer evolution. Here Laisné et al. describe how epigenomic heterogeneity generates dynamic...
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@MatLupien
Mathieu Lupien
11 months
📖 New review in Nature Reviews Cancer on how epigenomic heterogeneity drives tumour evolution! We dive into: Check it out if you're into epigenetics, single-cell tech, or the future of cancer therapy! 📖 https://t.co/WqJtxv1dH9
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nature.com
Nature Reviews Cancer - Single-cell epigenomic technologies are refining our understanding of cancer evolution. Here Laisné et al. describe how epigenomic heterogeneity generates dynamic...
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@StephAngers
Stephane Angers
11 months
We are recruiting a colleague in the Donnelly Centre at the University of Toronto. We are looking for an assistant professor in the broad area of functional genomics: https://t.co/b4xZ0cQMIJ closing date is Jan 16, 2025 @DonnellyCentre @UofT @uoftmedicine
jobs.utoronto.ca
Assistant Professor - Functional Genomics
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@MRSantosLab
Miguel Ramalho-Santos Lab
1 year
📣Sharing the latest research from the @MRSantosLab, just released on bioRxiv! We found LINE1 RNA promotes nuclear compartmentalization to repress the 8-cell state in human embryonic stem cells. https://t.co/uE06Xx3QcY 👇Key findings:
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biorxiv.org
The family of LINE1 transposable elements underwent a massive expansion in mammalian genomes. While traditionally viewed as a mutagenic selfish element, recent studies point to roles for LINE1 in...
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@MatLupien
Mathieu Lupien
1 year
🚨 BIG NEWS! 🚨 We are thrilled to welcome @biomodalhq as a sponsor for the 2025 Cancer Genetics & Epigenetics @GordonConf ! Their cutting-edge 6-base DNA sequencing technology is a game-changer in the field. 🌐 Learn more at https://t.co/h48L2kV1Ff Changing the game—together!
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biomodal.com
Capture genetic and epigenetic information simultaneously in a single workflow to better understand normal and disease biology.
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