
Mathieu Lupien
@MatLupien
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Senior scientist @Princess Margaret Cancer Centre, Prof @ UofT. BHAG: Conquer cancer by treating it as a disease of the chromatin. Also on Bluesky
Toronto, 🇨🇦
Joined July 2010
A jewel of a presentation on the history of chromatin. Always a pleasure to go back in time with those who helped shape it. I am grateful for the insights and stories shared by Drs. Ada and Donald Olins. https://t.co/d92wjrljRs
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Less than a month to go until the GRC on Hormone-Dependent Cancers! Looking forward to reconnecting with the community and sharing our latest on epigenomics of ecDNAs in tumor evolution. Hope to see you then.
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Less than a month to go until the GRC on Hormone-Dependent Cancers! Looking forward to reconnecting with the community and sharing our latest on epigenomics of ecDNAs in tumor evolution. Hope to see you then.
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@MatLupien we are looking forward to your presentation at #EREHD25 in Mexico this November🧬 Please share with your followers to let them know our early bird & talk submission deadline has been extended, so submit & register today! 🔗 https://t.co/kAMjifcs5t
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Are you currently in the ERE related field and want to find new collaborative opportunities? Join our Chairs @ChiappinelliLab, @shenhui1986, @twang5 & @paultaowu at the upcoming Endogenous Retrotransposable Elements & Human Diseases Conference this November! #EREHD25 🎙️Talk
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If you're into super-resolution microscopy, check out the new study from Myles Brown's lab showing dynamic, ligand-dependent changes in H3K27ac structure with implications for endocrine resistance.
biorxiv.org
Changes in gene expression regulated by ligand-dependent transcription factors such as estrogen receptor-α (ERα) involves the recruitment of coactivators including p300 that acetylates histone H3 at...
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🚨 New meeting this fall in Brussels! 🚨 Cutting-edge science, amazing colleagues, & a RARE career development workshop for trainees-covering pharma, consulting, writing, start-ups & more 🤩 #epigenetics2025 Registration is open!! @epicypher @FuksLab
https://t.co/SYynz5fyxi
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Big news! Recursion is a sponsor for the 2025 Cancer Genetics and Epigenetics GRC! With Recursion ( https://t.co/TRKJqyWAHF), this GRC conference is one where advanced technologies and human ingenuity will converge to outsmart cancer’s complexity. Join us
recursion.com
Dive into Recursion's innovative approach to decoding biology. Join our mission & explore what AI drug discovery companies can do. Contact us today!
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🌟What is epigenetics and why is it crucial for cancer research? Meet Dr. @MatLupien at @UHN @pmcancercentre, newly elected Fellow of the Royal Society of Canada. His work in cancer epigenetics is transforming how we can treat breast and prostate cancer: https://t.co/JyqUOKxZAl
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Epigenome Technologies Inc. is our latest partner of choice for the 2025 Cancer Genetics & Epigenetics GRC! 🔍 Discover their cutting-edge single-cell histone and transcription factor profiling technologies:
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Join our mission! Donate here to support innovation in cancer genetics. https://t.co/rkIQ04tps9 Stay tuned as we decode the mysteries of cancer!
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Thanks to our sponsors: @biomodalhq , @ZymoResearch , @NEBiolabs , T-ONE, @AtlasXomics , @OlinkProteomics , @GeneseeqInc , and @activemotif . Their support is vital in tackling cancer research challenges.
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🔍 What Secrets Lie Within Cancer Genetics? Scientists are racing to uncover clues in our genomes for new cancer treatments. The answers await at the 2025 Cancer Genetics and Epigenetics @GordonConf! https://t.co/8gG4NFQgkN
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#singlecell epigenomic technologies are redefining our understanding of cancer evolution. Now, @MartheLaisne, @MatLupien & @VallotCeline explain how epigenomic heterogeneity drives tumor cell state diversity through reprogramming and selection. https://t.co/FFwWAtUQxz
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📖 New review in Nature Reviews Cancer on how epigenomic heterogeneity drives tumour evolution! We dive into: Check it out if you're into epigenetics, single-cell tech, or the future of cancer therapy! 📖 https://t.co/WqJtxv1dH9
nature.com
Nature Reviews Cancer - Single-cell epigenomic technologies are refining our understanding of cancer evolution. Here Laisné et al. describe how epigenomic heterogeneity generates dynamic...
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📝Epigenomic heterogeneity as a source of tumour evolution Just out in Nature Reviews Cancer - a piece we wrote with @MatLupien and @MartheLaisne, a fantastic team work and such a pleasure to exchange & confront ideas on cancer epigenetics. 👉 https://t.co/3ChmgZqHTU
nature.com
Nature Reviews Cancer - Single-cell epigenomic technologies are refining our understanding of cancer evolution. Here Laisné et al. describe how epigenomic heterogeneity generates dynamic...
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📖 New review in Nature Reviews Cancer on how epigenomic heterogeneity drives tumour evolution! We dive into: Check it out if you're into epigenetics, single-cell tech, or the future of cancer therapy! 📖 https://t.co/WqJtxv1dH9
nature.com
Nature Reviews Cancer - Single-cell epigenomic technologies are refining our understanding of cancer evolution. Here Laisné et al. describe how epigenomic heterogeneity generates dynamic...
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We are recruiting a colleague in the Donnelly Centre at the University of Toronto. We are looking for an assistant professor in the broad area of functional genomics: https://t.co/b4xZ0cQMIJ closing date is Jan 16, 2025 @DonnellyCentre @UofT @uoftmedicine
jobs.utoronto.ca
Assistant Professor - Functional Genomics
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📣Sharing the latest research from the @MRSantosLab, just released on bioRxiv! We found LINE1 RNA promotes nuclear compartmentalization to repress the 8-cell state in human embryonic stem cells. https://t.co/uE06Xx3QcY 👇Key findings:
biorxiv.org
The family of LINE1 transposable elements underwent a massive expansion in mammalian genomes. While traditionally viewed as a mutagenic selfish element, recent studies point to roles for LINE1 in...
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🚨 BIG NEWS! 🚨 We are thrilled to welcome @biomodalhq as a sponsor for the 2025 Cancer Genetics & Epigenetics @GordonConf ! Their cutting-edge 6-base DNA sequencing technology is a game-changer in the field. 🌐 Learn more at https://t.co/h48L2kV1Ff Changing the game—together!
biomodal.com
Capture genetic and epigenetic information simultaneously in a single workflow to better understand normal and disease biology.
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