AtlasXomics
@AtlasXomics
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Accelerating Spatial Multi-Omics
New Haven, CT
Joined November 2020
🚨 New preprint! Dr. Marco Gallo’s lab used AtlasXomics Spatial ATAC‑seq to map chromatin in GBM and found nested epigenomic niches that drive cell‑state plasticity. Dive in: #Glioblastoma #CancerResearch #Epigenetics.
biorxiv.org
IDH -wildtype glioblastoma (GBM) is an aggressive brain tumor with poor survival and few therapeutic options. Transcriptionally-defined cell states coexist in GBM and occupy defined regions of the...
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Exciting News! FlowGel is now a routine part of YCGA’s toolkit, powering spatial epigenomics for Yale labs. Huge thanks to Bill Renock and Bony De Kumar for guiding the rollout and keeping the data flowing.🚀 #Epigenetics #Epigenomics #SpatialOmics
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Blazing-fast image creation – using just your voice. Try Grok Imagine.
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On a roll! 🎉 @YanxiangDeng’s lab + @zhouwanding drop a new preprint extending #DBiTseq to co-map DNA methylation 🧬 & RNA in the same tissue slice. Kudos @ChinNLee2021 & Hongxiang Fu!.
DNA methylation goes spatial! Introducing Spatial-DMT: a technology that co-profiles DNA methylation and transcriptome in the same tissue section. A fantastic collaboration with @zhouwanding lab. Kudos to Chin Nien Lee @ChinNLee2021 and Hongxiang Fu!
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🧬 Kudos to The Deng Lab @PennMedicine!.New Nat Comms: spatial FFPE-ATAC for DBiT-seq maps chromatin in archived brain, thymus & melanoma (10 µm) with AtlasXomics FlowGel featured. We’re working to bring this to researchers. Reach out to learn more!.#SpatialOmics #Epigenetics.
Our spatial FFPE-ATAC-seq is now published in @NatureComms! With extensive optimizations, it performs well across diverse tissues, unlocking the vast FFPE archive for spatial epigenomics. Big congrats to Pengfei Guo @pengfeo, Yufan Chen, and the team!
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🧩 Problem: IL-2 sparks regulatory T-cell activation, but where their chromatin rewires inside tissues was a mystery. 🛠 Solution: An Amgen R&D team led by Dr. Chi-Ming Li used AtlasXomics DBiT-seq spatial ATAC-seq to trace 20 µm-scale activation pockets and bZIP-TF footprints in.
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What a fantastic talk by @BeatrizGerFalc and @EllisLab_ at the Cedars-Sinai Single Cell and Spatial Omics Symposium! We’re proud to enable such exciting insights.
@BeatrizGerFalc representing @EllisLab_ discussing our spatial epigenomic analysis in #prostatecancer #spatialAtacseq. @PCF_Science @UrologySBUR @DrJasPlummer @LGMartelotto @RongFan8 @AtlasXomics
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New preprint from Dr. Xusheng Wang (UTHSC)! Using AtlasXomics’ spatial ATAC‑seq kit, the team mapped chromatin shifts in six‑month‑old 5×FAD Alzheimer’s mice and uncovered microglial TREM2 & VISTA hotspots that fuel neuro‑inflammation. Read ➡️
biorxiv.org
Abnormal epigenetic modifications, including altered chromatin accessibility, have been implicated in the development and progression of Alzheimer’s disease (AD). In this study, we applied spatially...
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Want to run spatial epigenomics in your lab? Our DBiT-seq kit makes it easy. Watch how it works! #epigenetics #spatialbiology
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Our CEO, Ken Wang, takes the stage at Nvidia’s GTC conference, sharing how our advanced computational pipelines are shaping the future of spatial epigenomics. Stay tuned for more innovative breakthroughs! #GTC #nvidia #epigenetics
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Unlock the hidden secrets of tissues with AtlasXomics! Discover how our revolutionary DBiT-seq enables spatial epigenomics. #Epigenetics #Genomics #SpatialBiology
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Discover how we’re turning the tide on tumor heterogeneity. Watch our new video to see how Atlasxomics’ cutting‐edge spatial epigenomic tools are powering breakthroughs in cancer research. #CancerResearch #SpatialEpigenomics
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Exciting to see our spatial ATAC-seq assay featured in @PAINthejournal! 🔬✨ This study by Urzula Franco-Enzástiga unveils the epigenomic landscape of the human dorsal root ganglion, shedding light on sex differences in nociceptive gene regulation. #SpatialEpigenomics #ATACseq.
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RT @DengYanxiang: Our spatial multi-omics technology that co-profiles five modalities is now published in Nature Methods @naturemethods! Hu….
nature.com
Nature Methods - Spatial-Mux-seq offers a multimodal spatial platform capable of profiling multiple molecular modalities, including the transcriptome, chromatin accessibility, histone modifications...
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We’re excited to take part in the Spatial Epigenomics Virtual Day hosted by the Center for Epigenomics at UC San Diego! This event brings together leading researchers to showcase the power of spatial epigenomic technologies across diverse research fields. Check out the full
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AtlasXomics is thrilled to see our collaborators at @LatchBio accelerate peak calling with a GPU-based MACS rewrite—achieving roughly 15X faster performance! This breakthrough significantly speeds up single-cell and spatial assays, enabling quicker epigenetic insights and.
Peak calling is important for epigenetics analysis but current tools aren't keeping pace with data generation. We're releasing a GPU implementation with ~15X speed up on industry workloads. A breakdown of the algorithm steps + benchmarks (1\N):
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Check out our White paper! While standard assays obscure crucial spatial and cellular differences, high-resolution methods like our spatial ATAC-seq illuminate the epigenetic underpinnings of cancer progression and therapy resistance. Learn more in our recent stomach cancer case
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Cheers to a year of breakthroughs at Atlasxomics—and an even more innovative 2025 ahead! Together, let’s push the boundaries of discovery. #epigenetics #genomics
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We had an amazing time hosting our Lunch and Learn at the Broad Institute of MIT and Harvard yesterday!. A huge thanks to the Spatial Technology Platform group for organizing and to everyone who attended, making it a great opportunity to connect with the research community.
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RT @RongFan8: Thrilled to share Perturb-DBiT — spatial unbiased in vivo perturb-seq with genome-scale CRISPR libraries! Hope you enjoy read….
biorxiv.org
Perturb-seq enabled the profiling of transcriptional effects of genetic perturbations in single cells but lacks the ability to examine the impact on tissue environments. We present Perturb-DBiT for...
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