MalmbergLab
@MalmbergLab
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The Malmberg Lab studies the functional regulation of natural killer (NK) cells and seeks to employ new insights in NK cell biology in cancer immunotherapy
Oslo, Norway
Joined January 2016
Great work, congrats. This is where we have to go.
Please check out our paper published in @NatureMedicine on our Phase I trial of AFM13-precomplexed cord blood NK cells in relapsed/refractory CD30+ lymphomas. Led by Dr. Yago Nieto and an outstanding team of coauthors and collaborators, this study marks the first clinical.
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Incredibly impressing ongoing work in the UK NK community. Thanks for the invitation @mjwsim. Looking forward to discussing more NK and KIR work in the coming days and to the yearly double 🎾 with @DrFran_Colucci.
Wow. What an amazing day. So great to see so much great science about my favourite immune cells. Thanks to everyone who came and especially @MalmbergLab for a stellar keynote.
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RT @MedCellPress: Online Now: Targeting HLA-E-overexpressing cancers with a NKG2A/C switch receptor
cell.com
The non-classical MHC class I molecule HLA-E serves as an important checkpoint inhibiting NK and T cell anti-tumor activity. Sætersmoen et al. engineer a switch receptor, using the binding domain of...
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RT @victorgreiff: We have an open 2-year postdoc position focusing on computational approaches to identify antigen-specific immune receptor….
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A cell intrinsic NKG2A/C switch receptor to overcome the critical HLA-E checkpoint. Fun collaboration with the Michel Sadelain lab. Michelle Sætersmoen, Ivan Kotchetkov, @LambertoTR @CoE_PRIMA @UniOslo_MED @Oslounivsykehus @CIM_Sweden.
Online Now: Targeting HLA-E-overexpressing cancers with a NKG2A/C switch receptor
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RT @lab_rezvani: Working with a great team including @NathanSinghLab & Stephan Mielke to organize @KeystoneSymp Immune #CellTherapy: Advanc….
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Very important and much needed funding to establish ATMP Norway, a multi-nodal national infrastructure for cell and gene therapy. Building on investments in GMP laboratories at @Oslounivsykehus and Haukeland University Hospital and a partnership with @UniOslo_MED.
Vi er svært glade for tildelingene fra @forskningsradet i dag, som bla. gir midler til å forsette å jobber med celle-genterapi, samt til forprosjekt for protonterapi. 1,3 milliardar kroner til forskingsinfrastruktur (.
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RT @LabWaggoner: GPR56 functions as an upstream checkpoint for migration of highly differentiated NK cells @J_Immunol @MalmbergLab @DanielP….
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Congrats @DanielPal88. Understanding the migratory behavior of NK cells is critical to overcome one of the major bottlenecks in the field: to make NK cells home to solid tumors. The inhibitory GPR56 axis is one piece of the puzzle.
Finally it's out and I can share with you all the collaborative effort done to produce this paper! Big thanks to @MalmbergLab and all the people who put so much effort into this.
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RT @mjwsim: Exciting work by @AmirHorowitz and team! Congrats to all. HLA-E and NKG2A Mediate Resistance to M. bovis BCG Immunotherapy in….
biorxiv.org
Mycobacterium bovis Bacillus Calmette-Guerin (BCG) is the primary treatment for non-muscle-invasive bladder cancer (NMIBC), known to stimulate inflammatory cytokines, notably interferon (IFN)-Îł. We...
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Thanks for this nice and thoughtful commentary of our work. We hope this approach will make a difference in the allogeneic cell therapy space for both T and NK cell based therapies.
Excited to share our commentary on a recent very elegant paper by @MalmbergLab @QuirinHammer and colleagues. A one-way street recognition approach to mediate allogeneic immune cel.
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RT @NatRevImmunol: Understanding NK cell heterogeneity
nature.com
Nature Reviews Immunology - Two papers in Nature Immunology provide a comprehensive atlas of human natural killer cells in health and in different types of cancer.
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RT @NatImmunol: Malmberg and colleagues provide a single-cell transcriptional reference map of healthy human NK cells and use this profile….
nature.com
Nature Immunology - Malmberg and colleagues generated a single-cell transcriptional reference map to investigate pan-cancer profiles of tumor-infiltrating natural killer cells.
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RT @QuirinHammer: Taken together, in this study in @CellStemCell, we demonstrate that modulating the immune synapse can be a promising stra….
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Comprehensive thread highlighting our most recent work now out in @CellStemCell describing a novel approach to increase persistence of allogeneic cell therapy products. Work led by amazing @QuirinHammer and @KarloPerica. @CoE_PRIMA, @Oslounivsykehus @UniOslo_MED @karolinskainst.
Happy to share the final work from my post-doc with @MalmbergLab published in @CellStemCell today extensive 15-post-🧵 below
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RT @lab_rezvani: Huge congratulations @MalmbergLab and co-authors on this groundbreaking paper! A significant advance for the field #NK #Ca….
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