Precision Immunotherapy Alliance
@CoE_PRIMA
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Precision Immunotherapy Alliance
Norway
Joined September 2022
Launch of PRIMA Mentorship Program! Mentors: Inger Sandlie and Hanne Mette Kristensen. Do you work on something interesting and important?
prima.uio.no
At the March Breakfast meeting, we will launch the PRIMA Mentorship program
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Mind-blowing visualization of immune cells in tissues by Ron Germain, who visited Oslo for the "zero" visit of the Scientific Advisory Board of @CoE_PRIMA. Inspiring to get early feedback from leading experts in the field: Ron Germain, @slinnarsson and Sine Reker Hadrup.
Fascinating guest lecture by Prof. Ronald Germain on "Visualizing Immunity – Insights from Multiplex Dynamic and Static Tissue-scale Imaging"! Hosted by @CoE_PRIMA and @NSImmun
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Fun collaboration with the Sadelain Lab @MSKCancerCenter, led by Michelle Saetersmoen, Ivan Kotchetkov and Lamberto Torralba-Raga. Targeting HLA-E Positive Cancers with a Novel NKG2A/C Switch Receptor @CoE_PRIMA @UniOslo_MED @Oslounivsykehus
https://t.co/oOmnzkQ7fC
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First monthly breakfast meeting of @CoE_PRIMA. Excellent report from the Target Identification Task Force. Insightful discussion on on-target/off-tumor toxicity, biologically informed target selection, single-cell genomics approaches and reference mapping. @UniOslo_MED
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1/n By applying probabilistic models implemented in scVI-tools, we created a transcriptional reference map of human blood and tissue resident NK (TrNK) cells from normal tissues including blood, pancreas, lung, breast, skin, prostate and brain.
biorxiv.org
The functional diversity of natural killer (NK) cell repertoires stems from differentiation, homeostatic receptor-ligand interactions, and adaptive-like responses to viral infections. Here, we...
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Through compilation of datasets from 39 studies comprising over 2 million single cell transcriptomes from seven distinct solid tumor types from >400 patients, we used this resource to train a pan-cancer model to extract and further investigate tumor-infiltrating NK cells.
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Very exciting work from @JOlweus in @CoE_PRIMA published in @NatureCancer describing a novel approach to target a shared neoantigen in acute myeloid leukemia. T cell power! @forskningsradet @UniOslo_MED @Oslounivsykehus
Excited to share our work, which shows that T cells targeting a shared neoantigen eliminate acute myeloid leukemia, including cancer stem cells, in vivo in a disease-relevant model @forskningsradet @ERC_Research @OsloCancer @UiO_LifeSci @Oslounivsykehus
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Last chance to apply for this postdoc position in my group!
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Important keynote lecture at @CoE_PRIMA kick off by Prof. Caroline Sophie Verbeke @Oslounivsykehus and @UniOslo_MED on the enormous challenge to develop effective therapies for pancreatic cancer. A very important early calibration with clinical reality. Taskforce #1 established
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@CoE_PRIMA, taking on the challenge to extend the success of precision immunotherapy to hard-to treat hematological malignancies and solid tumors.
Kick-off with Precision Immunotherapy Alliance at Hotell Riviera was @CoE_PRIMA! We are ready to join forces to combat cancer. A big thank you to the organizers for making such a great program @UniOslo_MED @Oslounivsykehus @forskningsradet @Cancertrial_ous
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Kick-off with Precision Immunotherapy Alliance at Hotell Riviera was @CoE_PRIMA! We are ready to join forces to combat cancer. A big thank you to the organizers for making such a great program @UniOslo_MED @Oslounivsykehus @forskningsradet @Cancertrial_ous
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Emma Haapaniemi and Ludvig Munthe, two PIs in @CoE_PRIMA, describing how they will leverage their deep knowledge on CRISPR editing and molecular immunology into new cancer therapies
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@CoE_PRIMA Kick-off! Inspiring to see the breadth and complementarity of the technological platforms made available through the formation of the Precision Immunotherapy Alliance. @UniOslo_MED @Oslounivsykehus @forskningsradet @LabMyklebust @JOlweus @AndersenJT @F_Lund_Johansen
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Cell therapy with adaptive NK cells being further developed in @CoE_PRIMA @UniOslo_MED @Oslounivsykehus @karolinskainst
What a great day this has been! Congrats @AlvaroHaroun on the brilliant defense of your PhD thesis at the Karolinska Institute. A million thanks to @lab_rezvani for your outstanding work as opponent via zoom.
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Selecting safe TCRs for therapy
Congrats to brilliant postdoc Zsofia Fôldvari on her paper outlining a much-needed strategy to select safe T-cell receptors! https://t.co/8HJRLYkpBZ A wonderful collaboration with M. Leisegang and team at @ChariteBerlin & our team @UniOslo_MED / @Oslounivsykehus . @Nature_NPJ
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A blogg post on PRIMA, this time in Norwegian.
med.uio.no
Immunterapi er behandling som hjelper immunforsvaret med å bekjempe kreft og andre sykdommer. Det er som å gi immunforsvaret vårt et detaljert kart og et kompass, slik at det selv kan finne og...
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Prima website now up and running:
prima.uio.no
PRIMA will develop the next generation of precision immunotherapy
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