Matthias Kirschner
@MMG_Kirschner
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Psychiatrist & Researcher @Hopitaux_unige | Geneva
Joined June 2019
Our latest article: Reconsidering evidence for Psychedelic-induce psychosis. A call to action for open-label trial #psilocybin therapy for psychosis #marco_solmi #systematicreview #SysRev #review #psychedelic
nature.com
Molecular Psychiatry - Reconsidering evidence for psychedelic-induced psychosis: an overview of reviews, a systematic review, and meta-analysis of human studies
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New Preprint! Our latest research, led by Marlene Franz, identifies orbitofrontal cortex thickness and network alterations as transdiagnostic markers of amotivation. Big thanks to all co-authors @BorisBernhardt @sofievalk @misicbata @bttyeo @philipphoman
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🌟 Exciting PhD Opportunity! 🌟 Interested in multiscale & multimodal neuroimaging in psychiatry with high-res 7MRI & big data @enigmabrains ? Apply for our 3-year fully funded PhD and join us @hug_ge, @Synapsy_UNIGE ! 📧 matthias.kirschner@hug.ch 🔗 https://t.co/tm6MWyzZM9
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This work is now out in @JAMAPsych! 🧠 https://t.co/pA2a1YbZUK Thanks to all coauthors and collaborators! @orygen_aus @MNC_Psychiatry @NSB_Lab @turnerinstitute @AFornito @YalePsychology @Mon_Bio_Imaging
jamanetwork.com
This case-control study models the processes that explain spatial patterns of gray matter volume loss in different stages of psychotic illness and assesses whether certain brain regions act as...
📈New & improved pre-print on the network-based spreading of grey matter changes across multiple stages of psychosis! We find that (1) 🧠volume changes are strongly constrained by axonal connections & (2) 🎯the hippocampus may be an epicenter of spread https://t.co/2s3cIlzj6y 1/n
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Big thank you to @sofievalk @MMG_Kirschner @BorisBernhardt @ClaraMoreau9 for launching ENIGMA's newest group early this morning - ENIGMA's Gradients Group (EGG) will study principles of brain functional organization throughout life +across disorders. More shortly! :)
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Excited to receive feedback on the preliminary results of our work in progress re:cerebellum-VTA connectivity linked to social amotivation in schizophrenia - led by superstar @FarnazDelavari
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Our paper using a precision phenotyping approach to characterise schizotypy is now out in @SchizBulletin, led by J Tiego: https://t.co/uN8K3Goh0v
academic.oup.com
Abstract. Schizotypy is a multidimensional construct that captures a continuum of risk for developing schizophrenia-spectrum psychopathology. Existing 3-fa
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Massive connectome resource Structural and functional whole-brain networks for 40k individuals Multiple resolutions, parcellation atlases and connectivity measures to select from and extensive QC. Mapped by @Sina_Mansour_L
Connectomes for 40,000 UK Biobank participants: A multi-modal, multi-scale brain network resource https://t.co/yx4s0kioQR
#biorxiv_neursci
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Extremely excited to share our Medrxiv preprint on sustained improvements in brain health and metabolic markers 24 months following bariatric surgery!
Sustained improvements in brain health and metabolic markers 24 months following bariatric surgery
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🧠Neuroimaging peeps🧠 our field is blessed with beautiful visualizations. Our preprint provides 3 tools to help move toward code-based & replicable visualization: 📗practical guide (why should I?) 📦package selector (which one?) 🏗️code template generator (how do I start?) 👇🧵
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@Hopitaux_unige @camillabellone @TranslationalML Thank you @Hopitaux_unige for the excellent support!
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📈New & improved pre-print on the network-based spreading of grey matter changes across multiple stages of psychosis! We find that (1) 🧠volume changes are strongly constrained by axonal connections & (2) 🎯the hippocampus may be an epicenter of spread https://t.co/2s3cIlzj6y 1/n
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New paper in Brain! Cortical thinning in isolated REM sleep behavior disorder occurs in regions with higher expression of genes invovled in mitochondrial functions!
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neuromaps: structural and functional interpretation of brain maps | https://t.co/8ojYaKmd57 GoogleMaps for the brain! By @rossdavism @JustineYHansen out now in @naturemethods 🧠🧰⤵️
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neuromaps is live! Here's the blog post I wrote, mostly so that I can send it to my parents when they ask me what it is I do: https://t.co/P9KyuqewDT So greatful for @rossdavism (!), my lab, and all neuromappers for what turned out to be a very collaborative + fun project 🥰
neuromaps: structural and functional interpretation of brain maps | https://t.co/8ojYaKmd57 GoogleMaps for the brain! By @rossdavism @JustineYHansen out now in @naturemethods 🧠🧰⤵️
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In our new preprint, we show that in the psychosis spectrum the vermal cerebellum plays a role in the integration of reward and cognitive function & its activity is inversely related to apathy severity. Led by the awesome @MMG_Kirschner & my brilliant mentor Stefan Kaiser
Cerebellar and cortico-striatal-midbrain contributions to reward-cognition processes and apathy within the psychosis continuum https://t.co/GeBq5AbiNg
#bioRxiv
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Mapping neurotransmitter systems to the structural and functional organization of the human neocortex | https://t.co/6ZSPbrWaMW Led by @JustineYHansen w/ super collaborators TLDR: we curate an atlas of neurotransmitter receptors and relate it to brain organization 🔐🧠🌎 ⤵️
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Our paper is out 🎉 Thanks to @philipphoman @johnmkaneny @LeuchtStefan & all. 📄 We found, increased variability in side effects of antipsychotics ➡️ suggesting stratified/personalized treatment allocation ➡️ could improve adherence & long-term health. https://t.co/l1INTLCfVR
academic.oup.com
Abstract. Side effects of antipsychotic drugs play a key role in nonadherence of treatment in schizophrenia spectrum disorders (SSD). While clinical observ
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Now out in @naturemethods | The ENIGMA Toolbox 🧰 An open-source python (🐍) and matlab (🌋) repository to access 100+ ENIGMA maps, visualize cortical and subcortical surface data, and relate neuroimaging findings to multiscale brain organization 🔗 https://t.co/ee9N32DkE7
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Visit us at @SOBP's poster session today to learn about infancy & early childhood brain development, neuroanatomical signatures of schizotypy, white matter microstructure in early onset psychosis, dysconnectivity in bipolar + more! #SOBP2021
@Leila_Nabulsi @nifti12 @MMG_Kirschner
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