Mark Allenby
@MCAllenby
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Senior Lecturer @UQ_EAIT. Bioprocess & bioplatforms for engineering blood & vessels🩸🧫🔬💻
Brisbane, Queensland
Joined June 2015
🚨Job alert in theory/math devbio 🚨 I’m currently advertising postdoc positions to join my group. We’re building reaction-diffusion models to understand some of the crazy things embryos can do. We are based in a beautiful part of Scotland. Please share! https://t.co/mIuYbbt0rV
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🚨 𝗡𝗲𝘄 𝗣𝗮𝗽𝗲𝗿 𝗔𝗹𝗲𝗿𝘁! 🚨Excited to share our latest work by @StphanePetrousk 🦴🦴 on macrophage mechanobiology https://t.co/rOh7rjLS3h
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This is a groundbreaking study for pericyte fans. We discovered the unique pericyte marker Higd1b which only labels pericytes without any off-target effect from other mural cells. @ATS_PC @AHAScience @vascularbiology
#Pericyte #PulmonaryHypertension 1/2 A subpopulation of Higd1b+ lung capillary pericytes 👉Migrate (w/o proliferation) to distal arteriole 👉Upregulate Vimentin 👉Acquire #SmoothMuscleCell identity (α-SMA, circumferential wrapping) in🐭Hypoxic PH 2 spatially resolvable
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Epigenetics Update - Viscoelastic extracellular matrix enhances epigenetic remodeling and cellular plasticity https://t.co/tdUseb7fen Song Li (UCLA) in Nat Commun #Epigenetics #ECM #CellularPlasticity --- Perfect for cancer, immunology, and aging; https://t.co/WmSYDGWPJD
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🚨New preprint from our #EDITLab, a joint effort from @S_Marzban (PhD in mathematics), Curtis Gravenmier (MD in Pathology), challenging the current "Cancer Stem Cell" hypothesis in ALL.
Our preprint "Cell state transitions drive the evolution of disease progression in B-lymphoblastic leukemia" We used a Markov model to estimate transitions between leukemic subpopulations, showing predictors of BCR::ABL1 status & MRD in B-ALL #EDITLab
https://t.co/LqOW9IEAmw
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Very happy and excited to share that this work is now published in @NaturePhysics ! https://t.co/4m79VrGRMn
@sciences_UNIGE @UNIGEnews @IP_Paris_ @Polytechnique
📢New preprint alert for vascular biologists, bioengineers and living matter physicists! " Interplay of actin nematodynamics and anisotropic tension controls endothelial mechanics. " Or the story of what happens to a living tissue when you pull on it ? 💪
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Only a few days left to apply! Don't wait, apply now!
We're hiring a PhD Student! We are looking for a creative and self-motivated researcher eager to learn, collaborate, and contribute to the future of creating biomaterials from supramolecular polymers. Come work @MERLN_UM @ibe_merln_UM
https://t.co/h8U7Rdb8MZ
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New research on aortic valve stenosis (AVS) highlights PTEN's role in preventing myofibroblast activation and promoting quiescence in valvular interstitial cells. This could be a potential target for AVS treatment. #AVS @AnsethGroup Read more: https://t.co/yu9QajbU2h
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It’s out! In this study, we investigated the response of endothelial cells to microgrooves and discovered different mechanisms for single cells and monolayers. https://t.co/4RqzIbCkS9 A thread for more details 🧵:
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Published in @CellCellPress: thrilled to contribute a bit to this amazing work led by @wang_yingxiao on developing “EchoBack” CAR T cells that respond to and can be tracked by ultrasound—enabling noninvasive control and imaging of cell therapies!!
cell.com
Sonogenetic EchoBack-CAR T cells were designed with an ultrasensitive heat-shock promoter screened from a library and a synthetic positive feedback loop that reprograms tumor engagement into CAR T...
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I can't get over these 3D spatial images in the latest preprint from @sorger_peter @ajitjohnson_n et al. The preprint is a roadmap on how to conduct 3D cyclic immunofluorescence using "thick" archival sections and precisely map cell-cell interactions https://t.co/CaACN9yQCW
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This is important. How to reduce feelings of physical and mental fatigue during your PhD.
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Join the International Data Week October 13-16 2025 in Brisbane! Under the theme "Data for Positive Change: Empowering Communities and Advancing Research," this event will unite global experts to explore pioneering data solutions. #DataInnovation #IDW2025
https://t.co/yzhuMalBGc
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CHOIR is officially published @NatureGenet. No more arbitrary decisions in clustering. Add this to your single-cell toolbox - it will save you so much heart ache. And now it can scale to millions of cells. Compliments of the very talented @cathrine_sant.
CHOIR is now online @NatureGenet! CHOIR is a new clustering method for single-cell data that evaluates whether clusters represent statistically distinct cell populations. CHOIR scales to millions of cells and works with single-/multi-omic data of any type! https://t.co/EKg20yMygH
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Excited to share our latest paper in @Nature in which we developed a microvasculature-on-chip system to learn more about how clots in the context of inflammation "get better" over days to weeks to months. Thanks to @ahmetfcoskun collaborating with us!
nature.com
Nature - In thromboinflammation, early tissue plasminogen activator administration directly improves endothelial barrier function, prophylactic defibrotide and enoxaparin suppress microvascular...
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The #tidyplots paper shares what went into shaping the package — including the controversial bits 😏 https://t.co/n58lCO3Epv
#rstats #dataviz #phd
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* New Nature Paper Alert * Here we introduce a hydrogel-based thromboinflammation-on-a-chip model coupled with multiplexed RNA fluorescence in situ hybridization in combination Link: https://t.co/prCuSOSyoc Fruitful collaboration with Prof. Wilbur A. Lam and Dr. Yongzhi Qiu
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Extremely happy to share our study on the regulation of HSCs in the context of myocardial infarction! Driven by two amazing scientists in my lab - Jasmin and Maricarmen and co-led with the awesome cardiologist Timo! Huge thanks to all our collaborators 👏🏻👏🏻 @mpi_ie @ETH_en
New publication by the @Nina_CabezasW lab & @Uniklinik_Fr / @ETH A vitamin A metabolite may offer a targeted therapeutic strategy for heart attack patients by regulating HSCs to minimize excessive inflammation and preserve long-term heart function. https://t.co/1tSSO1Kfc4
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Not every organ ages the same🤠 Skull💀Bone Marrow (incld Vasculature & VEGFA+ LSK #HematopoeticStemaProgenitorCell)🐭 Expands with age Skull BM even exhibits⏫age-dependent contribution to circulating leukocytes🥸 (photoconversion in Vav-cre;Rosa26-KikGR 🐭) Moreover, skull
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