The Nogales Lab
@NogalesLab
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The Nogales Lab at UC Berkeley. #CryoEM #Transcription #Microtubules #ChromatinModification #Telomerase Twitter account managed by lab members.
Berkeley, CA
Joined January 2019
Thrilled to share our new cryo-ET preprint on astrocytes, a collaboration with @FuLab here at @UCBerkeley, revealing the nm-scale cytoskeletal architecture of ramified astrocytes reminiscing in vivo morphology! Checkout how the cytoskeleton is organized in different compartments.
Excited to share our preprint on cytoskeletal organization in astrocytes! https://t.co/u3DvsTTn5N Postdoc @mewynne759 looked at microtubules, IFs/GFAP & actin along long elaborate processes. Wonderful to collaborate w postdoc @dharshinigopal & @NogalesLab on cryo-ET 🤓 1/x
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A unique honor to become a Foreign Member of the @RoyalSociety, together with my @UCberkeley colleague Stuart Russell and old friends like @Briggsgroup, @AsifaAkhtar1, Patrick Cramer @mpgpresident or @REMLehmann. Learning about great science and science history was a real treat.
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Very grateful to the Menéndez Pelayo International University @UIMP for awarding me an honorary doctorate last Tuesday, July 8th, in the incomparable setting of the Magdalena Palace (Santander). On Monday I enjoyed a conversation with those interested in my career and science.
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Abraham Watkins Law Firm is incredibly honored to have represented a remarkable family who suffered unimaginable tragedy — the loss of a loved one and life-altering injuries. This $60 million mid-trial settlement brings justice and closure to a family that placed their trust in
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Our work, co-led by @AlfredoFlorez and @NicholasLue, is finally out in @NatureSMB. Shout out to coauthors P.Grob, B. Kaeser, J.Fang, and Susanne Kassube for their contributions, and thanks to the reviewers for their suggestions that led to the final work. https://t.co/JANL7JQJca
nature.com
Nature Structural & Molecular Biology - Florez Ariza and Lue et al. use cryo-electron microscopy to investigate how the RECQL5 helicase regulates transcription. Their structural findings...
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So proud of the smashing success of the International Course in Biophysics co-organized with my @berkeleyMCB colleague Carlos Bustamante @BustamanteLab and University of Salamanca @usal
https://t.co/VlCe4Pl20M Course ends with a Keynote from Nobel Laureate Richard Henderson🥇
biophysal.org
First Summer International Advanced Biophysics and Structural Biology Course. Eva Nogales - Carlos Bustamante.
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We just built and released the largest dataset for supervised fine-tuning of agentic LMs, 1.27M trajectories (~36B tokens)! Up until now, large-scale SFT for agents is rare - not for lack of data, but because of fragmentation across heterogeneous formats, tools, and interfaces.
arxiv.org
Public research results on large-scale supervised finetuning of AI agents remain relatively rare, since the collection of agent training data presents unique challenges. In this work, we argue...
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Like a dream, my name next to that of @IsabelLAllende, and to be recognized my Universidad Internacional Menéndez Pelayo @UIMP. Soon after, Irene Vallejo @irenevalmore will receive the same honor. I feel proud to be linked to these truly inspiring, talented women! Thank you UIMP!
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👏👏Nuestra enhorabuena a la biofísica Eva Nogales @NogalesLab, cátedra JAE-Chair en el #CNB_CSIC por este merecido reconocimiento. ¡Enhorabuena a ambos investigadores por esta distinción!
🎓 Hoy, 19 de junio, la #UAM celebra el Acto de Investidura como doctores ‘honoris causa’ de la biofísica Evangelina Nogales y del catedrático y político Alejandro Tiana en el Edificio Plaza Mayor del Campus de Cantoblanco. ▶️ Síguelo en directo a partir de las 12 h en:
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Evangelina Nogales, doctora Honoris Causa, en la #BibliotecadeCienciasUAM @CienciasUAM
https://t.co/CkMp9cSJzp
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Deeply touched and honored by the Universidad Autónoma de Madrid, my alma mater, (@UAM_Madrid) making me Doctor Honoris Causa. Thank you to the Department of Physical Chemistry for nominating me for this recognition. It was a memorable day for me and my family👩🎓
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CO2 Coalition Chair Dr. William Happer discusses Climate "Science" on the Joe Rogan Experience
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Yesterday I had the pleasure to visit the Institute for Material Science in Madrid (@ICMM_com). Thank you to Dr. Pedro Serana for his invitation to talk about cryo-EM and our latest microtubule studies 🧩🔬🧬
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🎖️🔝 Evangelina Nogales es catedrática e investigadora y fue nombrada hija predilecta de #ColmenarViejo por sus enormes logros en los campos de la bioquímica, biofísica y biología estructural: https://t.co/22qnwiwRkM
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Que día tan emocionante volver a mi colegio en Colmenar Viejo y recibir el calor de sus profesores y sus alumnos. Gracias por darle mi nombre a vuestra biblioteca! 🥰
📚👩🔬 La reconocida científica colmenareña Evangelina Nogales inaugura la nueva biblioteca del que fue su colegio, el CPB Soledad Sainz 🏫🤗 Los alumnos le dieron regalos e hicieron preguntas a Eva en una jornada increíblemente emotiva ➕👇
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I spent a wonderful day in the Universidad de Córdoba at an interactive breakfast with faculty and students and giving a science presentation. Lovely to meet its Chancellor, Manuel Torralbo, and my friend and past collaborator Prof. Tina Domínguez-Martín.
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Schools must be open about their curricula because informed parents build stronger communities. Learn more about THINC by visiting our website, linked in our bio.
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Excited to have participated in the Third Symposium of Physical Chemistry in the Universidad Autónoma de Madrid last week and honored that the Prizes for best student talk and best posters carried my name 🥰☺️
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It was an absolute pleasure to visit the IBiS, to meet its scientists, interact with its students, and visit beautiful Sevilla 🥰
🟠SCIENCE | Thank you very much to Prof. Eva Nogales for sharing her outstanding and inspiring science with us. It was an honor to host her at IBiS!
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This week our lab had a double celebration: 1) Eva’s election into the Royal Society and 2) Zhenlin’s new job in Southern University of Science and Technology, Shenzhen, China @SUSTechSZ. He will be missed but we wish him success and joy in his independent career!
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Check out our review article on the structural and functional studies of retrotransposon proteins by @AkankshaThawani together with @CollinsRNPLab. https://t.co/N72Njjofhx
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A huge shoutout to our former grad student @SusanneKassube (now PI) for leading our lab’s original study back in 2013 and setting the stage for this work. If you’re interested, check out our preprint for more details and stay tuned for the full paper! 7/7
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Beyond a role in slowing down Pol II elongation, RECQL5 is known to decrease transcription stress. We propose that RECQL5 may help restart transcription from stalled Pol II by allosterically modulating Pol II’s translocation state. 6/7
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