Bo Li
@LilabUtsw
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Computational immunology lab at UT Southwestern Medical Center
Dallas, TX
Joined August 2020
Our Cancer Cell paper on mitochondrial transfer is highlighted by STAT news! It is one of the most popular Pharma-Biotech newsletters!
statnews.com
Images reveal that cancer cells pierce T-cells with nanotubes and steal their energy source, sapping the immune system.
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各位校友，我们非常荣幸地邀请您参加第十一届北京大学北美生物医学年会暨北大生科北美校友年会！本次活动将于2022年11月5日在UTSW举行。我们年会的网站链接在： https://t.co/bupikAaXOJ 我们热忱邀请北大生科校友，北大其他院系生物医学相关行业的校友，以及所有对生物医学有兴趣的朋友参加本次聚会!
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Our big analysis on the NK cell killer inhibitory receptor using UK bio bank and TCGA data is finally out!
link.springer.com
Background Natural killer (NK) cells represent a critical component of the innate immune system’s response against cancer and viral infections, among other diseases. To distinguish healthy host cells...
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.@LilabUtsw present #GIANA a tool that allows the rapid clustering of millions of TCR sequences in minutes, and can be used to identify TCRs potentially associated with cancer, infectious and autoimmune diseases. https://t.co/SkEpRE1G6Q
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Our manuscript has been under editorial consideration @SciImmunology by @IforRWilliams for 50 days! Is this the new norm since pandemic?
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Tomorrow (3/16) at 2:15-4pmEST, come join us at ENAR Session #71. Bulk Deconvolution and Single-cell Data Analysis Identifies Transcriptomic Dynamics in Tumor and Immune Cells as Potential Prognostic Markers for Cancer. @weisun2013 @LilabUtsw @elhamazizi and I will speak. 😊
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Maybe through epitope spreading
Since most cHL patients have MHC I defects, I suspect COVID-19 might stimulate a B/NK/CD4 response in the patient which eliminates the cHL tumor.
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The AIRR Community Meeting V Registration is live! https://t.co/B663NkxcT5 We have amazing speakers: @IG_lab @ematsen @TheArmita @LilabUtsw, Gordon Dale (Emory), Beatriz Carreno (UPenn), and COVID-19 Keynote Inaki Sanz! Dec 8–10! 🎉 Registration link: https://t.co/d26ibgmJP4
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Is my cough covid? https://t.co/zrpTOmOeGy
#AI deep learning finds some utility in a study of >5300 people @IEEEorg @IEEEXplore
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I worry that many people may have been infected at his events given his opposition to masks. Masks are very effective at reducing transmission. Discouraging masks is unnecessary and undermines public health. 80% of the people who died of #COVID19 in the US didn’t need to die.
I fear Trump’s #COVID19 diagnosis will be a disaster. He’ll be fine: early diagnosis, 24h care, early remdesivir and Covid antibodies. He’ll get better & say Covid is no big deal. People will believe him, let down their guard, and 100Ks will die when they can’t get the same care.
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Online Now: The PD-1/PD-L1-Checkpoint Restrains T cell Immunity in Tumor-Draining Lymph Nodes
cell.com
Dammeijer et al. show that PD-1/PD-L1 interactions occur frequently in tumor-draining lymph nodes (TDLNs) and that specific targeting of PD-L1 in the TDLN induces an effective anti-tumor immune...
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Using a tool called VirScan to study coronavirus #antibody responses in #SARSCoV2-infected & control individuals, @harvardmed scientists identified signatures of cross-reactivity and severity. They used this antibody data to design a rapid diagnostic tool. https://t.co/JFHpkcHq45
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I think this is the best tweet of the day and thank you @tmprowell !!!!
Fun fact: the MUTE button was invented in 1956 by Robert Adler, an Austrian Zenith Radio Corporation engineer. It was 1 of 4 buttons on his Space Commander 400, the first marketed TV remote control. Robert, everyone on conf calls & #Twitter salutes you. 🙌
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.@YaleIBIO, @YaleMed researchers sequenced 100,000+ cells, 50,000+ T cell receptors in cerebral spinal fluid from healthy individuals and patients with #multiplesclerosis. They found several differences in certain #Tcell characteristics between cohorts: https://t.co/GQnjqnsifK
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Dr. Jim Allison: "The reason I'm thrilled about this is I'm a basic scientist. I didn't get into these studies to cure cancer. I wanted to know how T cells work." #NobelPrize #endcancer
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Americans are divided into those who believe in science or in fiction now, sadly
If your friends or family think #COVID19 is “just the flu” or want it to rip through society to get to herd immunity, consider sharing my piece on #longhaulers with them. I outline the growing body of research & highlight why many still struggle months after an initial infection.
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