Sethi_Lab
@LabSethi
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Dedicated physicians & scientists determined to improve outcomes in patients with gastrointestinal cancers through basic and translational research @DanaFarber
Boston, MA
Joined November 2020
A great collaboration with my friend @JunQiLab. We screened a small molecule library targeting epigenetic regulators curated by Jun’s team using our dual reporter system. The ensuing mechanistic work required innovative chemical and rigorous molecular biology.
Proof-of-concept: Epigenetic reprogramming could one day be a new therapeutic path in colorectal cancer. @Nilay_Sethi explains how histone acetylation shapes CRC cell fate in this @AGA_Gastro study:
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RT @BraunMDPhD: We are looking for an associate research scientist and lab manager for our translational cancer immunology lab at Yale. P….
jobrxiv.org
Post a job in 3min, or find thousands of job offers like this one at jobRxiv!
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RT @DanaFarberNews: New research in @ScienceMagazine: Pancreatic cancer–restricted cryptic antigens are targets for T cell recognition. Res….
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RT @DanaFarberNews: Targeting resistance to RAS inhibition in pancreatic cancer: @DanaFarber's @andrewaguirremd presents in an #AACR25 sess….
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Devastating!.
There are days in life that shake you. I’m shattered 💔 to share that I just found out that the US Government terminated my 2024 NIH Director’s Early Independence Award (~$2 million), threatening my long-promised assistant professor job at @Columbia & academic career. 1/🧵
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RT @Intestinal_Cell: 🥼 Scientists at @DanaFarber, including @Nilay_Sethi, create a duel endogenous reporter system by editing the SOX9 and….
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RT @DanaFarberNews: Congratulations to @DanaFarber's William Freed-Pastor, MD, PhD, and Megan Insco, MD, PhD, @InscoLab for receiving the A….
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RT @ShanaAdise: PhD programs are pausing admissions to graduate school due to NIH indirect cost cuts. See the growing number of programs he….
docs.google.com
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RT @bureaucatliu: Just heard that Vanderbilt rescinded all of its PhD offers because of NIH and NSF funding cuts and that Washington Univer….
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“Science knows no country, because knowledge belongs to humanity, and is the torch which illuminates the world.” -Louis Pasteur.
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It is for the pursuit of the unknown, from the distant cosmos to the subatomic. It is timely and timeless. It brings purpose to millions around the world, including me. Let’s do what we can to keep it alive!.
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That being said, I will focus on what we can do: perservere, be resilient, find a way, inspire and be inspired. Science has no country (or political party) - Louis Pasteur. It is for everyone. It is for the betterment of society.
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Basic, translational, and clinical research, academic medicine, healthcare progress and innovation, and STEM education are facing serious threats and unprecedented destablization. I am concerned. There are detrimental consequences to the recent mandates by our government.
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STAND UP FOR SCIENCE – March 7, 2025. Washington DC and Nationwide. Because Science is for everyone.
standupforscience.net
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RT @srikosuri: It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendr….
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RT @ItaiYanai: Postdocs need a place to learn and practice the scientific creative process. Tomorrow we start the "Postdoc Night Science" c….
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RT @HenryYin19: As a PI, most of my lab skills have deteriorated. I barely know how to do anything in the lab, but I'm pretty good at mult….
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RT @m_rashidian1: 1. Excited to share our paper published in @Nature today, introducing CD45-PET as a robust approach for noninvasively im….
nature.com
Nature - A non-invasive in vivo positron emission tomography imaging approach detects inflammatory disease using various preclinical models.
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