Lindsey Dzierozynski
@LDzierozynski
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PhD Candidate in the Johns Hopkins Biochemistry and Molecular Biology Program | Sears Lab Member | Metabolism Enthusiast | Chicagoan at Heart | š³ļøāš | she/her
Joined October 2019
RT @radscientist_: [emailing my committee at 2:48am] would you guys still let me graduate if I was a worm.
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Excited and proud to finally see this published!.
Out today in @cellhostmicrobe, @LDzierozynski, @DrCindySears, and I comment on shaping of the gut microbiome by host genes. @HopkinsMedicine @JHMed_ID @bloombergkimmel .
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Congrats to Juan!!! (or should I say Dr. Apiz-Saab, my Muir lab partner in crime)! I know that you'll continue to do incredible science wherever you go and whatever you set your mind to. Always happy to hear all the great news coming from the Muir lab.
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RT @NatureMicrobiol: A family of peptides secreted by the gut helps to keep fungal members of the microbiota under control, according to aā¦.
science.org
Paneth cellāderived pancreatic polypeptide YY, in its full-length form, acts to check the invasive potential of commensal fungi.
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RT @NatMetabolism: Online now! Methionine restriction-induced sulfur deficiency impairs antitumour immunity partially through gut microbiotā¦.
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RT @NatMetabolism: RESEARCH BRIEFING. The authors determined the metabolome and microbial composition of the liquid luminal content of theā¦.
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RT @fawwazanvilen: so there's a species of parasites which doesn't have mitochondria, the *only* known multicellular animal to not have theā¦.
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RT @Muir_Lab: New paper on model system our team designed to study how metabolic stress affects the biology of pancreatic tumors: https://tā¦.
elifesciences.org
Analysis of the tumor microenvironment reveals that pancreatic tumors experience metabolic stress caused by immune cell degradation of the amino acid arginine, and that pancreatic cancers cope by...
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Very excited and proud to see this work finally published! @japizsaab is a science rockstar and I'm proud to be first co-authors together! Grateful as well for the many others who played a huge part in making this possible! Cheers everyone!.
Kinda surreal to see this finally out, but checkout the final version of our work on arginine metabolism in PDAC. Huge shout out to my co-1st author and amazing researcher @LDzierozynski .
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RT @robinsall: A short thread about Adam Dowdell's excellent chemotaxis paper, just out in @CurrentBiology. It shows how combinations of liā¦.
cell.com
Competition between different ligands for the same receptor type can explain how cells can drive negative chemotaxis in which cells migrate away from a chemical repellent. Dowdell etĀ al. show that...
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RT @exosome: Insane paper. Ketogenic diet suppresses th17. #campbellneurosciences.$tsoi.
cell.com
Ketogenic diets differ from high fat diets in that they alter the gut microbiome to affect the level of gut Th17 cells.
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RT @NatureMicrobiol: ICYMI š. Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease @NatureMedicā¦.
nature.com
Nature Medicine - A novel multi-omics workflow, combining gut microbiome metagenomics, metatranscriptomics and metabolomics, enabled the identification of the microbial pathways responsible for the...
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RT @BoehmeMarcus: Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila inā¦.
nature.com
Nature Microbiology - Systems genetics reveals interactions between host and microbial phenotypes in the murine gut, including a role for Akkermansia muciniphila in the production of...
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RT @NatMetabolism: #NatMetabPicks | In @Cell_Metabolism, Takeuchi et al. (@riken_en) evidence abundance of a commensal species of the familā¦.
cell.com
The mechanistic linkage between obesity and gut microbiota remains elusive. Takeuchi etĀ al. report that a member of commensal microbiota prevalent in individuals with diabetes and obesity produces...
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RT @victornizet: BACTERIAL HUNGER GAMES.E. coli and V. cholerae participate in a biofilm. But E. coli persuades the V. cholerae to occupy tā¦.
pnas.org
Biofilm formation, including adherence to surfaces and secretion of extracellular matrix, is common in the microbial world, but we often do not kno...
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RT @chidley_chris: Iām excited to share a new #cancer #metabolism preprint where we explore nutrient transport in cells and tumors in CRISPā¦.
biorxiv.org
Blocking the import of nutrients essential for cancer cell proliferation represents a therapeutic opportunity, but it is unclear which transporters to target. Here, we report a CRISPRi/a screening...
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RT @Mito_Redox: Delighted to see this - it represents a painstaking development of. a method by Fay Allen, overseen by Andrew James. Thiā¦.
febs.onlinelibrary.wiley.com
To assess the distribution of metabolites between mitochondria and the cytosol, we developed a rapid fractionation procedure. We take mouse heart/liver and within ~ā30ās stabilise the distribution...
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