Karthik Hullahalli
@KHullahalli
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Postdoc studying bloodstream infections in the Waldor lab (he/him)
Joined June 2019
Are you interested in studying the function of infection-stimulated bile metabolites or Listeria pathogenesis? We are hiring at all levels !!!
tingzhanglab.org
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After an incredible 8 years in Boston, I've embarked on a new adventure by starting my own lab at Cornell University this September! Our mission is to unravel translation control mechanisms in bacterial pathogens, laying the groundwork for new therapeutics.
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I am excited to share our latest research in @NatureComms, uncovering how an RNA base editor converts cytidine to pseudouridine! Here are the takeaways from our paper 1/6 https://t.co/ZQqkjZelR0
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Very excited to share our work elucidating the stepwise reaction mechanism of a unique RNA base editor that converts cytidine into pseudouridine! https://t.co/tQaMrDwQoI
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Very excited to share the preprint of my postdoc project in the #WaldorLab !! Proteomic interrogation of the pathogen-host interface in cholera #cholera #HostPathogenInteraction #proteomics #StayTuned
@biorxiv_micrbio @biorxivpreprint
https://t.co/QrbVmTqbWd
biorxiv.org
The microbial cell surface is a critical site of microbe-host interactions that often control infection outcomes. Here, using the infant rabbit model of cholera, which provides an abundant source of...
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Check out our new preprint from the @palmer_lab on a novel glycolipid in GBS and it’s impact on pathogenesis: in collaboration with @KdoranLab and Ziqiang Guan: a mini 🧵
Streptococcus agalactiae MprF synthesizes a novel cationic glycolipid that promotes brain entry and meningitis https://t.co/2ZzwXLlLVB
#biorxiv_micrbio
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It's out! Latest from the #WaldorLab "Type I interferon remodels lysosome function and modifies intestinal epithelial defense" Happy to be part of this amazing work by Hailong Zhang! #Salmonella
https://t.co/GuDuWRxc25
pnas.org
Organelle remodeling is critical for cellular homeostasis, but host factors that control organelle function during microbial infection remain large...
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Muc2 mucin limits Listeria monocytogenes dissemination and modulates its population dynamics https://t.co/dDgo6dcCoi
#biorxiv_micrbio
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Dedicating my first tweet to my very first publication from the @joeBondyDenomy Lab out at @NatureMicrobiol !! Here, we look at how anti-CRISPRs are not only adopted by phages to combat CRISPR but also PLASMIDS👩🔬🧫🦠 https://t.co/ESF3FfzkMi
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Our newest #WaldorLab preprint! Very happy to be part of this story using #Salmonella as a probe to identify IFN-I as a regulator of epithelilal #Lysosome function.
biorxiv.org
The degradative activity of lysosomes is essential for cellular homeostasis and also functions in innate defense against intracellular microbes. Pathogens commonly modify lysosome and other organelle...
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"I feel for the devoted researchers who began their careers expecting to revel in the joy of discovery, only to find their love of the subject squeezed out, replaced by fear and anxiety."
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Publication doesn't have to be a zero sum game. Leadership from @ACasadevall1 and others shows us a different path towards excellence. @BallouLab
https://t.co/doPaeyzOqV
@ASMicrobiology #mSphere
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Congrats! Nice work and great way to start 2020 !
Very excited to share my first paper as a postdoc in the Laub lab!! Thank you to @lennice_castro, Chris Reisch, @monicasguo and @michael_laub8 for a great team work! #caulobacter #alphaproteobacteria #CRISPRi
@mbiojournal @MITBiology
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Amazing talk by @monicasguo at @harvardmed for the Microbiology Symposium: GapR as a sensor for (+) supercoiled DNA
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It’s up!! Presenting our new oral inoculation model of Shigella infection. https://t.co/hpwqwHIHb1
#shigella #modelsystems #WaldorLab
biorxiv.org
Shigella species cause diarrheal disease globally. Shigellosis is typically characterized by bloody stools and colitis with mucosal damage and is the leading bacterial cause of diarrheal death...
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