Jonathan Kuhn
@JonathanAKuhn
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Cell biology postdoctoral fellow in the Devreotes Lab at JHU studying directed cell migration. Microscopy lover and recovering Mitosis fan.
Baltimore, MD
Joined May 2017
Thanks to Dr. Vibha for the update! One thing I’d add is that the reviewers’ push to validate our computational model led to a new main figure demonstrating we can predict changes in motility, which I’m particularly happy with!
Insightful #postLight just uploaded by @SVibha1 👀 She revisits work from @JonathanAKuhn and team, originally posted as a preprint and now published in @NatureCommunications postLight:
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New work out in @NatureComms! Thank you to my collaborators and editors! https://t.co/3FTyJJB3lr
nature.com
Nature Communications - Here the authors use synthetic tools to control elements of the cytoskeleton during amoeboid migration. They uncover two feedback loops sufficient to generate cell polarity;...
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It's June, which means it's time for me to review what to do if someone who needs an interpreter asks for medical advice and whether or not I should click on emails where it says I've won a prize
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Excited to see this paper out in the themed collection "Soft Matter Pioneering Investigators": https://t.co/jqk2IWNQqr Grateful for my advisor Andrej Košmrlj for his help, as well as @KayTrue for patiently teaching us about membranes!
pubs.rsc.org
Phase separation plays an important role in spatial organization and material distribution of biological membranes, which are essential for crucial biological functions ranging from signaling and...
Just posted our work on pattern formation of lipid domains in membranes! Motivated by some beautiful experiments, we discussed how a combination of phase separation and elastic deformation leads to patterns in an asymmetric membrane. Suggestions welcome!! https://t.co/DkdF6EM7X7
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(Unrelated to Politics): If I had a good working knowledge of Python and neural networks, what's a good starting point to learn about how to make predictions about one fluorophore from another? Talking both about formatting the data and choice of network architecture
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Former eLife editor in shambles today (I kid, I kid)
BREAKING NEWS The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.
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ever wonder how a cell makes lamellipodia? @MuziyueW in @OWeinerLab @C3STC reveals a key piece to the puzzle: the WAVE complex forms curvature-sensitive stacked linear arrays that could nucleate sheet-like structures https://t.co/b3fOtDLFft
biorxiv.org
Cells generate a wide range of actin-based membrane protrusions for various cell behaviors. These protrusions are organized by different actin nucleation promoting factors. For example, N-WASP...
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The moment I've been waiting for, to showcase the direct visualization of actin nucleators and their cooperative yet competitive assemblies in the #actin cytoskeletal network!! Check out some of our videos below and supplementary files https://t.co/Y78THcrO07
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As a parent of a young child that wakes me up at 6 AM every morning, 12 PM talks without real food should be illegal
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Thanks so much to Dr. Singh and PreLights for highlighting my preprint!
"The cytoskeleton talks back and has a bi-directional influence on cell polarity"... Check out my latest @preLights post 👇covering the @biorxivpreprint from the team of Peter Devreotes with a response from first author @JonathanAKuhn. https://t.co/AtlYgzjHPI
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"The cytoskeleton talks back and has a bi-directional influence on cell polarity"... Check out my latest @preLights post 👇covering the @biorxivpreprint from the team of Peter Devreotes with a response from first author @JonathanAKuhn. https://t.co/AtlYgzjHPI
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More work from the Devreotes lab from the man with the worst NBA takes in lab. Glycolytic enzymes in waves!
Please check our new preprint work showing how a novel form of subcellular localization of glycolytic enzymes to cell membrane provides a new level of spatiotemporal regulation of metabolism, serving as an alternative explanation for the "Warburg effect":
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New paper out in Biorxiv! Big thanks to my collaborators and labmates!
Complementary Cytoskeletal Feedback Loops Control Signal Transduction Excitability and Cell Polarity https://t.co/c3HiXzgDjg
#biorxiv_cellbio
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Has to be my single favorite methods paragraph of all time
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In fairness half-assing proofreading someone else's writing is maybe the most human ChatGPT could do
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What you spend your time doing after over a decade of training in a highly specialized field
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Me when my cells are too sparse to work with today
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