Johana Misas Villamil
@JohanaMisas
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Scientist, mother, wife, daughter, sister, friend
Joined January 2019
Our new preprint, in collaboration with @KamounLab and contributions from @jonathandgjones, @AdamWu9527, and @JiorgosKourelis labs, on the exciting discovery of organelle targeting by an activated helper NLR is out! 👇
🚨 A new twist in #NLRbiology! 🚨 Excited to report on the surprising mechanism where the helper NLR NRG1 targets organellar membranes to trigger immunity unlike canonical CC-NLRs, which function at the plasma membrane! 1/11 🧵 https://t.co/jqIquRcz9D
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It was great to communicate at the Gordon Conference on Plant Proteolysis 2025🌱Excellent presentations, informal environment and interdisciplinarity. Congratulations to the organizers 👏 Greetings to all new colleagues and friends 🙋🏻♂️
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Computational design of serine hydrolases
New research in Science represents a notable step forward in designing enzymes from scratch. With a new approach, researchers designed an enzyme that uses a covalent intermediate to catalyze a two-step reaction, analogous to what many proteases do when breaking apart proteins.
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This is like AlphaFold, but for protein localisation rather than folding It's a deep learning model that predicts a protein's subcellular compartment based on its amino acid sequence alone:
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🔥 Let’s stop pretending agriculture and conservation are at odds. 🔥 We can feed the world AND protect it. 🔥 The future depends on how we grow. Are we moving forward or backward? Don't just take my word for it, read for yourself: https://t.co/7KUq262Mp8 9/9
pnas.org
Research investments in crop improvements, including by national and international agricultural research centers, have made significant contributio...
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Excited to share our new publication on a novel MAMP peptide conserved across nematodes, insects, and fungal pathogens, along with the RLK essential for its signaling. https://t.co/P5gaK60SFj
biorxiv.org
Plant-parasitic nematodes (PPNs) cause major agricultural losses worldwide, yet the molecular basis of plant immunity against these pathogens remains poorly understood. To investigate how plants...
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Abstract submission is now open! Share your discoveries in plant-microbe interactions this July in Cologne, Germany. Share your findings: https://t.co/T2zu7XrS3S The deadline to submit is March 11. #2025ISMPMI #GlobalResearch #PlantMicrobeScience
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We've been sold a lie for decades: "ORGANIC" and "NATURAL" are not only better for you-they're better for the planet. Sounds great, right? Except it's not true. Here's the story of how these labels became some of the most successful marketing deceptions of our time 🧵:
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Europe has romanticized organic farming to the point of harm. We promote it as the gold standard, but the truth is, organic farming is less efficient, more resource-intensive, and not as “green” as we think. Here’s the story of Europe’s organic farming myth 🧵: 1/
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Europe made a colossal mistake: They banned genetically modified organisms (GMOs) while the rest of the world embraced them. Now we rely on imports, pay more for food, and miss out on sustainable agriculture. Here’s the story of Europe’s GMO debacle 🧵:
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Want to predict post-translational modifications Phosphorylation/Acetylation/Ubiquitination/Acylation/Methylation... of proteins of interest?👇 PhosphoSitePlus https://t.co/XW0L54ex4V
@NAR_Open 2014 https://t.co/SfkeyuF2UR Even powered up by recent human Kinomes An atlas of
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Obligate biotrophic fungi cause some of the most devastating diseases on cereals. They are also highly difficult to study…. It is truely remarkable how well described the barley and what powdery mildews are. Here the current knowledge and summary of great resources. Enjoy!
Get a First Look! 👇 🌱🌾Technical Advances Drive the Molecular Understanding of Effectors from Wheat and Barley Powdery Mildew Fungi https://t.co/NinVB74Tye
@IzzySaur
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Nature research paper: A rare PRIMER cell state in plant immunity https://t.co/3pfBTJq8SC
nature.com
Nature - The development of a molecularly defined spatiotemporal atlas of pathogen-infected Arabidopsis thaliana leaves reveals specific cell states that have distinct roles in plant immunity.
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We are recruiting a Full Professor in Molecular Biology with a focus on Biological Engineering. Details can be read up in the advertisement on Nature Careers. Please share with researchers who are active in this field. https://t.co/gxdjgSrldD
nature.com
The Center for Molecular Biology of Heidelberg University (ZMBH), the Carl-Zeiss-Stiftung Center for Synthetic Genomics (CZS Center SynGen), and th...
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TIR-mediated immune signalling through the EDS1:PAD4:ADR1 node is conserved in monocots and dicots #spotlight #MolecularPlant
https://t.co/0zmUeYPtt5
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Arabidopsis WALL-ASSOCIATED KINASES are not required for oligogalacturonide-induced signaling and immunity
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Concluding: within-field diversity for Zymoseptoria is huge! We should keep this in mind when designing protection strategies. I.e. R gene deployment or fungicide use. see also:
bsppjournals.onlinelibrary.wiley.com
Click on the article title to read more.
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“There is nothing wrong with dividing natural and unnatural. The problem comes when we attach a value to the distinction: natural is good or better than unnatural. Natural is not always better, but this flawed thinking has influenced research.. in ag”
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