Caroline Jefferies
@JefferiesLab
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Irish Immunologist focused on #Lupus, #Autoimmunity, & promoting #WomenInScience! Love my garden & proud #ChickenLady!! Views mine. [email protected]
Joined August 2016
A low-key kick-off to our Irish campaign 1) for all Irish health insurers to provide access to cancer immunotherapies recommended by our oncologists immediately; 2) for fair access to immunotherapies in the public system; 3) Ireland to tax plan for future CAR-T & miRNA therapy.
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Today was the "soft-launch" of our media campaign to get all Irish health insurers fund cancer immunotherapy #FundImmuno . I have been overwhelmed with the support (over 5000 shares in a day, just on LinkedIn). Thank you. @LayaHealthcare do us right!
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🧵 1/@LayaHealthcare why are you not funding life saving EMA approved immunotherapy (that is funded by @VHI) for my colleague Prof Bernie Mahon @FundImmuno ? All Laya customers should be aware of this? @DonnellyStephen @SimonHarrisTD @NSAI_Standards @MichealMartinTD
@HIAuthority
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Excellent article on IL17+ neutrophils in #SexDifferences in #Alzheimers from @OlegButovsky in @NatureMedicine
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@CedarsSinai Board of Directors annual meeting featuring an inspiring vision statement by @CFerroneMD, chair of surgery…busy clinician and #cancer #immunologist working on new #CarT treatments
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Delighted to share our recent paper:a-ketoglutarate‐dependent KDM6 histone demethylases regulate Interferon Stimulated Gene expression in Lupus - Montano - #ACRJOURNALS Arthritis & Rheumatology - Wiley Online Library
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Delighted to share our recent paper:a-ketoglutarate‐dependent KDM6 histone demethylases regulate Interferon Stimulated Gene expression in Lupus - Montano - #ACRJOURNALS Arthritis & Rheumatology - Wiley Online Library
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When MIT molecular biologist Nancy Hopkins quantified how much more lab space men were given, she unleashed a US-wide reckoning about how women are held back in academia
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Another successful @CREWHS_CS Symposium featuring Prof. Caroline Whitacre @3Whitacre delivering the keynote on #SexDifferences in #AutoimmuneDisease
First keynote @CREWHS_CS Dr. @3Whitacre presenting on #MultipleSclerosis and multi factorial nature of sex differences #SABV
@CMECedarsSinai @CedarsSinaiMed @CedarsSinai
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Happy #StPatricksDay2023 after all the rain the #SantaMonica hills behind us are looking distinctly Irish!
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Join us THIS Saturday, March 18th, for our 2023 Global Symposium: #TheFutureofLupus - a scientific symposium delivering leading-edge #lupus education! Join us for free resources, emerging lupus info & incredible panels from 8am-12pm PST. Register: https://t.co/gXl1SlDaWI
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Congrats to @ivanvujk & Gislaine Martins @IBD CedarsSinai @CedarsSinaiMed AAI Congratulates 2023 Recipients of Intersect Fellowships for Computational Scientists and Immunologists
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#Parenting is probably one of the most fulfilling but challenging jobs any of us #workingmums can do. As a parent of an adult child I know my love, worries and fears are as intense now as when he was tiny but my power to help has changed #WomenInSTEM
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While anyone can develop #lupus (including children & men), 9 out of 10 people who have lupus are women. In honor of #IWD2023, we celebrate the strength of all the incredible #lupuswarriors impacted by this disease. Your resilience inspires us & we’ll never stop fighting for you.
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Happy International Women's Day! We're celebrating women who have changed the world. Here's all of the amazing women who have received the #NobelPrize and their remarkable achievements at the time of the award. Who are the women who inspire you the most? #IWD2023
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A fantastic study by @FrezzaLab that shows fumarate regulates mtDNA release and IFN-I induction through the cGAS-STING pathway-exciting research nd for #Lupus immunopathology -Fumarate induces vesicular release of mtDNA to drive innate immunity | Nature
nature.com
Nature - Fumarate metabolism regulates the innate immune response through a mechanism in which high levels of fumarate result in the generation of mitochondrial-derived vesicles and the release of...
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Trinity and Cambridge scientists unearth potential new therapeutic target for inflammatory diseases such as Lupus and sepsis - News & Events | Trinity College Dublin @CedarsSinaiMed
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Our paper is out today in Nature linking Fumarate Hydratase to inflammation. Big thanks to all our collaborators and congrats to Alex Hooftman @AlexHooftman Christian Peace @ChristianPeace and Dylan Ryan @metab_innate for their great ideas and hard work. https://t.co/j9NZeKzAjR
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A timely day for its publication on #InternationalWomensDay given that #Lupus affects predominantly women!
Delighted to be part of this fascinating study in @Nature led by @AlexHooftman @metab_innate showing that Macrophage fumarate hydratase restrains mtRNA-mediated interferon production - important implications for #Lupus and #Interferonopathies
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