Alex Hooftman
@AlexHooftman
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Postdoctoral Researcher at EPFL. Ethnically Dutch but culturally English.
Joined April 2020
RT @tristramryan: Are you interested in #immunometabolism but not sure where to start?. Introducing our new book “Metabolites as Signals in….
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RT @RyanLab_MBU: Massive congratulations to @AlvaCasey3 on her first author paper from her PhD: 'Pro-inflammatory macrophages produce mitoc….
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RT @ZottaAlessia: Thrilled to share the work of my PhD,out in @ScienceAdvances!🥳We discovered that complex III regulates IL-10 production i….
science.org
Mitochondrial respiratory complex III sustains IL-10 production in macrophages and promotes tumor-mediated immune evasion.
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RT @epflSV: 🎉🎉🎉Congratulations to Andrea Ablasser who has won the 2024 Liliane Bettencourt Prize for Life Sciences from @Fondation_BS! .Rea….
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Had a cracking time meeting all of the @EMBOFellows @embl in Heidelberg. Some amazing science being done across Europe and further afield! Also very grateful to @EMBO for funding our research over the last few years #emboat60
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RT @la_meirelles: 🚨🔬Excited to share our new paper now out in @NatureMicrobiol!. Using Tn-seq + live imaging in engineered airway organoids….
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RT @ChristianGPeace: Excited to share a new paper from my PhD work along with @shaneOCarroll4 from the @laoneill111 lab on how the metaboli….
nature.com
Nature Metabolism - O’Carroll and Peace et al. provide a mechanism for the induction of type I interferons by the immunomodulatory compound itaconate, which involves inhibition of succinate...
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RT @epflSV: 🎉🎉🎉Congratulations to Andrea Ablasser who has won the Paul Ehrlich and Ludwig Darmstaedter Prize @PaulStiftung with Glen Barber….
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RT @yin_mau: @ZottaAlessia @laoneill111 and I wrote a review on the most up-to-date research on the role of the ETC in immunometabolism. Be….
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RT @ZottaAlessia: Immunometabolism lovers,the review I wrote with @yin_mau and @laoneill111 for @TrendsImmuno is out!🤩📚We focused on the ro….
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RT @RyanLab_MBU: Are you interested in the field of #immunometabolism?. Check out the final version of our (@AlexHooftman @ChristianGPeace)….
karger.com
Abstract. Background: Innate immune cells play a crucial role in responding to microbial infections, but their improper activation can also drive inflammatory disease. For this reason, their activa...
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RT @Tim_Sparwasser: #IUIS2023: brilliant talk by Luke O‘Neill @laoneill111 drawing our attention to the most important (and our favorite) o….
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RT @ChristianGPeace: Delighted to share our latest piece all about how the Krebs cycle enzyme Fumarate hydratase regulates immunity from @l….
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RT @RyanLab_MBU: @AlexHooftman, @ChristianGPeace and I wrote a short open access commentary on the role of #mitochondria and nucleic acid s….
onlinelibrary.wiley.com
Click on the article title to read more.
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Scientists of Twitter! The world needs more reminders that we’re living breathing human beings. @shaneOCarroll4 🇮🇪🤕.@ChristianGPeace 🇮🇪🇺🇸.@tristramryan 🇮🇪🏳️🌈.@AlexHooftman 🇳🇱🇬🇧.@Ultimatehorst 🇩🇪🇪🇺. #internationalscientists. Quote tweet this with a picture of you doing not-science
Scientists of Twitter! The world needs more reminders that we're living, breathing human beings. Quote tweet this with a picture of you doing not-science.
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RT @EmDay4: Happy to share our work showing that the NRF2 activating compounds, DMF and 4-OI, induce the secretion of the anti-inflammatory….
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RT @FrezzaLab: Immunometabolism community: We seek a postdoc to work at the intersection between immunity, metabolism, and inflammation wit….
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Honoured to be a small part of this important discovery led by the fantastic @tristramryan demonstrating the anticoagulant capabilities of DMF and 4-OI, published in @NatureComms. Congrats!.
Buzzing to share my PhD work out now in @NatureComms. We've found a procoagulant type I interferon-tissue factor axis in macrophages, and the anti-inflammatory drugs DMF (clinically approved) and 4-OI are anticoagulants via inhibition of type I IFN-TF!.
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