https://t.co/ZW2nTNCHyG

#legday in the books. Only 3 more workouts till a well deserved deload and the start of a new mesocycle.

@drjamesdinic @AlexJLeaf @MetabolicUncle @JamieVernon @joerogan And this is also a big reason why low T3 is so common in Type 1 diabetics. Chronic low insulin states and inconsistent glucose availability both suppress T4 to T3 conversion. The thyroid gland is usually fine, it’s the metabolic signal of low insulin and low fuel that drives T3

Gym bros: Beware Husla Pads. This is a piece of junk. Save your money. When used, the pad will spin to the non padded side whether you use the straps (sold separately BTW) or not. I have to stop in the middle of every set and readjust. Terribly defective product IMO.

Breakfast: 449g egg whites 2 packs of Instant Oatmeal

The study used DEXA to measure “muscle loss” but DEXA can’t distinguish between water, glycogen, muscle fibers, organs, or any other non fat, non bone tissue. So when people quote “1/3 lean mass lost" a big chunk of that (I'm guessing a vast majority) is almost certainly water

I blame @drjasonfung for this fasting crap. I used to fast all the time until I learned how MPS actually works. Yes we’ve got plenty of stored fat for energy. But we have no way to store amino acids. When your body needs to repair/replace lean tissue, it’ll pull from muscle.

“I don’t want to diet and exercise. I don’t care if I die at 69 instead of 78” I hate to breaks it to you but it doesn’t go down like that. Modern medicine will keep you alive for 10-20 years and during that time you’ll be in chronic illness and lots of pain. Every day will be

TLDR From a pure physiology standpoint, a well-controlled T1D with high muscle mass, high insulin sensitivity, and structured insulin timing has several hypertrophy advantages over a non-diabetic: higher peripheral insulin activity ability to time insulin peaks synergistic

6. You have controlled access to one of the most powerful hypertrophic hormones Insulin is: anti-catabolic synergistic with IGF-1 highly permissive for mTOR essential for amino acid transport (via LAT1 and SNAT2 systems) a driver of intramuscular hydration (osmotic swelling)

5. Large skeletal muscle mass drastically improves glycemic variability Hypertrophy increases muscle sink capacity via: increased GLUT4 density increased glycogen storage improved mitochondrial function reduced inflammatory cytokines As muscle mass goes up, insulin sensitivity

4. You can maintain high insulin signaling on ultra-low dietary fat Extremely low-fat diets (<20–30g/day) in non-diabetics often create: reduced insulin secretion reduced T3 conversion decreased leptin impaired recovery drops in testosterone higher perceived exertion T1Ds do

3. Muscle contractions + exogenous insulin = synergistic GLUT4 recruitment Resistance training independently recruits GLUT4 via calcium/calmodulin and AMPK signaling. Combine that with exogenous insulin (PI3K/Akt pathway) and you get a multiplicative effect, not just additive.

2. You can precisely time insulin with carbohydrate availability Non-diabetics release insulin reactively. T1Ds with good control can release it strategically. That matters because insulin’s peak muscle actions occur when: plasma glucose is available amino acids are present

1. Exogenous insulin bypasses hepatic first-pass extraction In non-diabetics, endogenous insulin is released into the portal vein, where the liver extracts 40–80% of it before it ever reaches systemic circulation. Subcutaneous insulin does not undergo this first-pass clearance.

Most people assume Type 1 diabetes is a disadvantage for muscle growth, but that’s based on outdated thinking. Once you understand insulin physiology, glucose disposal, and nutrient partitioning, you realize T1D gives you several unique advantages that non-diabetics can’t access.

Now that 🦃 is over, 10 week mini cut starts today! One of the benefits of religiously tracking calories daily for the last ~3 years is I know pretty much where I need to be to gain, maintain, and lose body fat. I use MacroFactor which also helps determine one's 'Calories

@DKThomp Meanwhile what one of the fittest people in the world eats during a record-breaking ride from Canada to Mexico. Real fitness = antifragility.

Happy Thanksgiving! ❤️ @PlanetFitness

Time to work 💪🦃

Stuff's not bad