James DiNicolantonio
@drjamesdinic
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Doctor of Pharmacy and Cardiovascular Research Scientist
Joined October 2014
Many people in the CARNIVORE & LOW CARB space don't believe in LOW-GRADE ACIDOSIS. That's because they have not researched this field or looked at the clinical studies on CARNIVORE/HIGH ANIMAL PROTEIN DIETS. Let's take a DEEP DIVE into how this works and let's cover the human
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POTASSIUM eliminates MOST of the HARMS from HIGH SALT intakes!
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That outdoor brick oven isn't connected to anything. No kitchen. No house. Just vibes and one enormous orange vegetable. Peak architectural planning. Out now on Steam 👇
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Interesting…I point out a flaw in @CharlesMBrenner reasoning ie letting him know that higher linoleic acid levels associating with better outcomes is likely due to reverse causation and cite references to support this and instead of wanting to learn more he *UNFOLLOWS ME*.
@CharlesMBrenner The association with higher linoleic acid levels in the body and worse health outcomes is due to *reverse causation*.
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Liposomal creatine does NOT improve its absorption or reduce bloating because creatine is already well absorbed, and the thing that causes side effects (the osmotic effect) happens before liposomes could ever make a difference. There’s ZERO evidence for Liposomal creatine…just
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High linoliec acid may absolutely be a cause of cancer. Linoliec acid oxidizes in our stomach to lipid hydroperoxides and aldehydes which are genotoxic. All tissues and lipoproteins are more susceptible to oxidation if they contain more linoleic acid. Linoleic acid in
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@CharlesMBrenner References: Associations between omega-6 polyunsaturated fatty acids, hyperinsulinemia and incident diabetes by race/ethnicity: the Multi-Ethnic Study of Atherosclerosis. Clinical Nutrition. 2020. Natalie L WEIR 1, Sarah O NOMURA 1, Brian T STEFFEN 1, Weihua
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"If the “requirement” for choline is taken as that level of choline which is necessary to reduce level of liver fat to a minimum, results of this study indicate that rats fed on diets containing 30% of butter fat have a higher “requirement” for choline than those receiving 30% of
pubmed.ncbi.nlm.nih.gov
Effect of different dietary fats on choline requirement of rats
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In studies comparing seed oils versus animal fats, high refined carbohydrate intakes bias the results in favor of seed oils because long-chain saturated fats have lower oxidation rates than polyunsaturated fats. This means that when combined with high carbs, saturated fats from
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References: Associations between omega-6 polyunsaturated fatty acids, hyperinsulinemia and incident diabetes by race/ethnicity: the Multi-Ethnic Study of Atherosclerosis. Clinical Nutrition. 2020. Natalie L WEIR 1, Sarah O NOMURA 1, Brian T STEFFEN 1, Weihua GUAN 2, Amy B KARGER
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Seed oils are NOT healthy! You can read some of my publications here which covers this in more detail DiNicolantonio JJ. The cardiometabolic consequences of replacing saturated fats with carbohydrates or Ω-6 polyunsaturated fats: Do the dietary guidelines have it wrong? BMJ
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Regarding ApoB as being a risk factor for CV disease... I am very much under the impression that the risk with ApoB is largely driven by ApoB particles that are 1.) Carrying high amounts of linoleic acid, and 2.) Lacking antioxidants like ubiquinol, lutein, zeaxanthin,
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Seed oils are NOT healthy! You can read some of my publications here which covers this in more detail DiNicolantonio JJ. The cardiometabolic consequences of replacing saturated fats with carbohydrates or Ω-6 polyunsaturated fats: Do the dietary guidelines have it wrong? BMJ
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Say it with me people….CORRELATION does NOT equal CAUSATION.
The current physical activity guidelines undervalue vigorous activity. Vigorous activity may be 4–9× more potent than moderate activity for reducing all-cause mortality, cardiovascular disease, diabetes, and cancer risk. The exercise guidelines assume a 2:1 ratio between
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Eating healthy isn’t dieting… It’s eating the way humans always did. We only call it a “diet” because junk food became the norm. Somehow sickness is normal, and health looks like discipline. Healthy eating isn’t weird… it’s the reset button.
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Crunches are cool, but they’re not a magic eraser for late-night snacks. Work out hard, eat smart. That combo hits different. Abs are built in the gym, but they’re revealed in the kitchen.
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Eating healthy isn’t dieting; it’s the default setting we drifted away from. Just because eating fake food is now normal, doesn’t mean eating real food is “extreme”. No wonder people think wellness is a project. Going back to basics isn’t restrictive. It’s the most human
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Eating healthy isn’t “restriction”. It’s how humans have always eaten. Call it what it is…normal eating.
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