Ian Watson Lab
@IanWatsonLab
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Canada Research Chair II/Associate Professor Goodman Cancer Inst., Dept Biochemistry, McGill University/Investigator RI-MUHC/CCTG Melanoma Disease Site Co-chair
Montréal, Québec
Joined June 2018
Clinical trials have been repeatedly shown to result not only in better future outcomes (including removal of failed interventions) but benefit the participants. Wonderful to be teaming up with @CDNCancerTrials @queensu
📣 We're happy to join forces with @CDNCancerTrials to announce three new projects funded through our Pan-Canadian Project program! 📣 The projects focus on increasing the effectiveness of #immunotherapies for the benefit of cancer patients. Story ▶️ https://t.co/WnRYySuBJt
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The Canadian Cancer Trials Group (#CCTG) is joining forces with @marathonofhope (#MOHCCN) to conduct three pan-Canadian projects with the goal of increasing the effectiveness of #immunotherapy for cancer patients. #CancerResearch #ClinicalTrials
https://t.co/oQEgN9n2z4
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Check out our latest preprint on MAPK-targeted therapies for patients with MAP2K1/MEK1 mutant cancers. Hopefully helpful for molecular tumor boards! @DrDrAprilRose @EmmaJRousselle @ANowakowski11 @annalazaratos @NicolaNormanno @ArielleElkrief @MLadanyi
medrxiv.org
PURPOSE MAP2K1/MEK1 mutations are potentially actionable drivers in cancer. MAP2K1 mutations have been functionally classified into three groups according to their dependency on upstream RAS/RAF...
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This is a really cool study by Elena Kuzmin (@ElenaK35) and Morag Park, two fantastic colleagues in Montreal. Our (*now graduated) student Kento Abe @nbcc_ltri was able to provide interaction mapping for C4orf19, a new CCM3 (PDCD10) + kinase (GCKIII) interaction partner.
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Absolutely thrilled & humbled to touch down in #Philadelphia to discover @ProfGLongMIA & I selected as joint nominee for NSW 2024 @ausoftheyear. Testament to our incredible @MelanomaAus team & selflessness of every patient & their family who contributes to our ongoing research.
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I want to highlight a preprint from my colleagues, Boris Bastian and Dirk Hockemeyer, that unravels the mystery of the dysplastic nevus.
biorxiv.org
TERT promoter mutations (TPMs) are frequently found in different cancer types, including approximately 70% of sun-exposed skin melanomas. In melanoma, TPMs are among the earliest mutations and can be...
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Excited to share our work “Insulin Receptor Loss Impairs Mammary Tumorigenesis in Mice“. Led by @LaurenMPodmore and @KatPlz, our study reveals a major function of INSR in breast/mammary tumour initiation, likely independent of its kinase activity. https://t.co/ErPwZ79ip2
cell.com
Insulin receptor (INSR) is found in most human breast cancers. Podmore et al. demonstrate that INSR contributes to cancer development in two mouse models representing major human breast cancer types...
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His impact and legacy will forever inspire us. We will be honouring Dr. Jerry Pelletier's incredible legacy through various events and gatherings. Stay tuned for updates on how we will celebrate his life. Let's come together to commemorate a remarkable scientist and friend.
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We are saddened to share the news that iconic McGill professor Jerry Pelletier has passed away. Our condolences to his family, friends and colleagues. Learn about his life and work in this profile from last year: https://t.co/AxcIQzrrUm
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It is with heavy hearts that we share the passing of Dr. Jerry Pelletier, an esteemed alumnus of the Sonenberg lab and a pioneering figure in the field of mRNA translational control. He was more than a colleague; he was a cherished friend and mentor to many.
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Adrian Thorogood is our Data Governance Manager. He met up with researchers from @IanWatsonLab at the run in Montreal!
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Had a great #TerryFoxRun2023 in Montreal with the @IanWatsonLab and the members of the @McGillGCI ! What a lovely event to promote fundraising for cancer research. There is still time to donate at https://t.co/ZQwUy0kMYS
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🚨 New funding announcement! 🚨 We're delighted to announce the winners of our inaugural MOHCCN Health Informatics & Data Science Awards! The recipients are eight promising, early-career data scientists in Ontario, Quebec and Nova Scotia More ▶️ https://t.co/dzuLMmytmQ (🧵)
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“This study puts Canada at the forefront of microbiome research by showing we can safely improve patients’ response to immunotherapy through fecal transplants.” 🗨️ Dr. @BertrandRouty, MOHCCN Clinician-Scientist Learn more ▶️ https://t.co/PAkYnUXkNa
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Claire’s talk was a highlight of this years Banff signalling meeting. Learn about adaptation of BioID for measuring signalling changes with 5 minute time slices. And she’s looking for an independent position.
The last @CSMB_SCBM seminar before we take a summer break will happen next Tuesday July 11 @ 9am PT/12pm ET! This month we have two 🇨🇦 postdoc speakers and we'll hear about counteracting cellular aging and temporal/spatial EGFR signaling! Sign up here: https://t.co/KaUKvFQDQh
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A mind-blowing paper has come out today in @Nature In 2016, JC Venter Institute scientists trimmed a bacterial genome to its barest minimum required for life to synthesize what they called a "minimal genome" ( https://t.co/CNDeaZUmYd). Today, a group of scientists from
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In patients with advanced #melanoma, fecal microbiota transplantation from healthy donors combined with anti-PD-1 #immunotherapy was well tolerated with a response rate of 65% in the first-line treatment setting @smimmunology @SchulichMedDentto
https://t.co/OEz1ZLmPKD
nature.com
Nature Medicine - In patients with advanced melanoma, fecal microbiota transplantation from healthy donors combined with the anti-PD-1 inhibitors nivolumab or pembrolizumab was well tolerated with...
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Seven GCI scientists ranked top 100 in Canada for their disciplines: @SonenbergLab, Gros, Pelletier, @MoragPark1, Giguère, Tremblay & Yang We are privileged to have distinguished researchers who have influenced their fields of research to such extents https://t.co/D2yflCsmMJ
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In 2016, I came up with a plan to change cancer patients' gut microbiome before immunotherapy. Now we have multiple trials doing that. Here are the results of the MIMic trial with the help of John Lenehan, @BertrandRouty, Mike Silverman, @Our_MicroBiome
https://t.co/Hx3JpEOkjE
nature.com
Nature Medicine - In patients with advanced melanoma, fecal microbiota transplantation from healthy donors combined with the anti-PD-1 inhibitors nivolumab or pembrolizumab was well tolerated with...
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Press Release: New study published in @NatureComms identifies amino acid to potentially treat aggressive cancers https://t.co/MUDk1lhz48 Co-lead by Prof. Sidong Huang @HuangLabMcGill @McGillGCI and Prof. Yemin Wang @GCI_Cluster @bccancerfdn
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