HongchengMAI
@HongchengM
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Neuroscience fans. Associate professor in SUN YAT-SEN UNIVERSITY. Doctoral students advisor. Previous lab member in Helmholtz Munich center ITERM.
Munich, Bavaria
Joined November 2018
We are introducing LipiGo ๐ค A programmable DNAโlipid nanocarrier ๐งฌ with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. by @cerenkimna @kalorintschi
https://t.co/moldTeozmj 1/n
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Amazed to share our new study published in @CellCellPress revealing how the liver contributes to weight loss in cancer via disruption of a circadian regulator and secretion of catabolic factors. Big thanks to @FiskerSchmidt, S. Herzig, @BerrielDiaz ๐งต๐ https://t.co/2fvK9ExTMO
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ICYMI: #Stroke June #EditorPick: Hypoxia induces neuronal release of CircOGDH in small extracellular vesicles to interact with endothelial cells for enhancing blood-brain barrier repair during acute ischemic stroke. @HongchengM #AHAJournals
https://t.co/dVkPnklUL5
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๐๐ข๐ฅ๐ฎ๐ซ๐ ๐ข๐ฌ ๐๐ง๐๐ฏ๐ข๐ญ๐๐๐ฅ๐: ๐๐จ๐ฐ ๐ญ๐จ ๐๐ฎ๐ข๐ฅ๐ ๐ ๐๐๐ฌ๐ข๐ฅ๐ข๐๐ง๐ญ ๐๐๐ ๐๐ฎ๐ฅ๐ญ๐ฎ๐ซ๐ In my last posts, I shared my experiences with building a team and focusing. When you look from the outside, you might see a story of quick, impactful papers and major
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Proud to share our latest @CellCellPress paper. We present a novel immune population termed PNS microglia that regulate neuronal soma size throughout evolution. https://t.co/wyHCnc6HJ9
#Microglia#PNS#NeuronalSomaSize#Macrophage#BodySize#Neuroimmunology#Evolution (1/8)
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A huge day for mapping in life science! โthe mammalian brain, most extensive yet https://t.co/vUErk0ToPc
@AllenInstitute โa comprehensive map of the human cell going sub-cellular https://t.co/7LJnFqEkTT โcomplete ape genomes https://t.co/SbpBI9ZaYY
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#STROKE: Hypoxia induces neuronal release of CircOGDH in small extracellular vesicles to interact with endothelial cells for enhancing blood-brain barrier repair during acute ischemic stroke. @HongchengM #AHAJournals
https://t.co/dVkPnklUL5
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Read it here: #Nanoparticles #TissueClearing #BiomedicalResearch #3DImaging #DrugDelivery #Nanomedicineย https://t.co/Yk4pRXdOE8
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Check out our latest review on Tissue Clearing & Its Application in Nanoparticle Development! โจ We explore how tissue clearing techniques enable 3D imaging of nanoparticles in whole organisms, offering insights into biodistribution and therapies. @erturklab @zhouyi_rong
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Check out our latest review on Tissue Clearing & Its Application in Nanoparticle Development! โจ We explore how tissue clearing techniques enable 3D imaging of nanoparticles in whole organisms, offering insights into biodistribution and therapies. @erturklab @zhouyi_rong
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One limitation of the whole mouse level for disease study is imaging spead. Please Check SIAT Professor Bi'new work: High-speed mapping of whole-mouse peripheral nerves at subcellular resolution
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opening new field of tissue clearing applications.
LNP/mRNA therapeutics and AAV-based approaches require cell-level precision to achieve success without significant toxicity to other cells. To enable this, we now introduce SCP-Nano๐ค in @NatureBiotech: an AI-based technology for precision nanotechnology. https://t.co/1YniGZr4O4
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Spike persistence & neurological sequelae of COVID-19 @erturklab reports SARS-CoV-2 spike protein persists in skull-meninges-brain axis, inducing inflammation, neurodegeneration-related changes, and increasing the brainโs vulnerability to further injury https://t.co/BXbIRYSFq6
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Our new study shows that SARS-CoV-2 spike protein accumulates & persists in the body for years after infection, especially in the skull-meninges-brain axis, potentially driving long COVID. mRNA vaccines help but cannot stop it๐ฌ๐ง ๐ฆ ๐งต๐@cellhostmicrobe
https://t.co/IEGx7HIrXf
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Brand new AI based 3D segmentation method for whole mouse
Imagine seeing a disease's impact on every cell in the body. Now, you can! We introduce MouseMapper, an AI tool to reveal system-wide disease perturbations. MouseMapper showed obesity-induced changes in facial nerves & body-wide inflammation ๐๐ผ๐งต https://t.co/2sPQra70xx
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Out first joint lab retreat day 2. First version of Mai lab photo is online now.
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Our First Joint lab retreat day 1. All good chef are delayed by scientific research.
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Congratuations! A great work from Erturk lab contributes to 3D pathology and making it more avaliable for all scientists.
The July issue is live today! https://t.co/WkJdk9BPCS The beautiful cover comes from the @erturklab and shows c-Fos+ neuronal mapping in whole mouse brains. See paper: https://t.co/dOaFfRzyLj
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The July issue is live today! https://t.co/WkJdk9BPCS The beautiful cover comes from the @erturklab and shows c-Fos+ neuronal mapping in whole mouse brains. See paper: https://t.co/dOaFfRzyLj
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