Guezguez lab
@GuezguezL
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Group Leader @DKTK_ @DKFZ @UnimedizinM @uni_mainz, working on Aging Hematopoiesis, Epigenetics and Leukemia microenvironment
Germany
Joined June 2020
🚨New sequential #epigenetic strategy to overcome BRD4/BET inhibitor resistance in #AML! Excited to have contributed to this research led by Daniel Sasca, Brian Huntly & team, paving the way for new therapeutic approaches in leukemia. #CancerResearch @UnimedizinMainz @uni_mainz.
BET followed by p300 inhibition improves cytotoxicity in AML and is optimally deployed during early stages of resistance to BET inhibitors. #myeloidneoplasia
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RT @CEpigenomics: A just-published paper in Nature Biotechnology from the lab of C4E Director Bing Ren describes a novel technique, Droplet….
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🌟 Thank you to @IRCM_MTP @adjiane for the warm invitation to visit your institute and showcase our work in #leukemia #microenvionment and #epigenetictherapy. Excited to share ideas and engage with such a vibrant scientific community and potential collaborations. Merci! 🇫🇷 💊👨🔬.
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Got the opportunity to attend this fantastic #FirstTHEMALeukemiaSymposium organized at @cdf1530 looking forward for upcoming meetings and interactions by @ThemaSaintLouis 👏🥼🇫🇷.
THEMA Saint-Louis Institute aims to be a hub for research, innovation, and education in leukemia. With 26 speakers and 350+ participants, this symposium was a great opportunity to gather researchers. Let’s strengthen connections in the leukemia community !
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RT @jmartinrufino: I am thrilled to share my preprint with #AlexisCaulier and others in @bloodgenes lab, showing how systematic mapping of….
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RT @gamonasterioo: The value of ‘wasting time’ on deep thinking is often overlooked in a scientific ecosystem increasingly tainted by Wall….
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RT @karin_prummel: Happy to see this fun and exciting collaboration from my PhD seeing the light (land?)! ⭐️ Another puzzle piece found abo….
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Great new finding on deciphering the HSC "cloud" of mutlipotent/committed progenitors within the human bone marrow #hematopoiesis using #CYTOF approach. Congrats @YeEun_Kim__ @Bendall_Lab @WJGreenleaf 👏👏🧬🦴.
Our human multipotent lymphoid progenitor paper is finally out! After revision, we added more in vitro validations of the lympho-myeloid potential of this HSPC population. Lots of thanks to @Bendall_Lab & @WJGreenleaf.
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Thank you @TheBinderLab and Marieke Essers @hi_stem_lab for organizing this fantastic #interferon Symposium 👏🏻👏🏻 great opportunity to present our work and build up new connections, I learned a lot! ✍️🧬🔬.
Second day of the Interferons Symposium- as enthusiastic an audience as yesterday, and again fantastic keynotes: today by Jan Rehwinkel @UniofOxford and Ana Martìn-Villalba @molneurolab. Thank you to everyone who contributed to this meeting- it was amazing!
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RT @ImmunoEditor: Now in @SciImmunology: @crow_lab & @casanova_lab #review the #human monogenic disorders underlying insufficient & excessi….
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RT @MKolleg: Invitation to the Marsilius Lecture "Scientific Progress and the Need for Oversight" by @G_Q_Daley, Dean of @harvardmed . We'r….
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RT @VJHemOnc: LIVE from #iwMDS24 | @UwePlatzbecker of @UKL_Leipzig discusses telomerase inhibition in LR-MDS . Explore the potential of tar….
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RT @emmamgroarke: Very nice talk from @CarmeloGurnari highlighting germline predisposition to MDS/AML due to #DDX41 variants at #iwMDS24. h….
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RT @Dr_AmerZeidan: What an amazing day full of great talks & great discussions at the #iwMDS24 this is how we move the #MDSsm field forward….
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RT @DavidSteensma: When I was a fellow 25 yrs ago, John Bennett who was then the best known person in #MDSsm field took the time to stop by….
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RT @emmamgroarke: @dralainmina from @NCIResearchCtr gives a great overview of the @NIH myeloid malignancies program! #MDSsm #AMLsm @VJHemOn….
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RT @imbmainz: This year the annual meeting of the German Society for Aging Research (DGfA) is taking place at IMB. In collaboration with t….
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Excited to be part of this Annual Meeting of the German Association for #Aging Research at @imbmainz 🇩🇪 our lab from @UnimedizinMainz will be highlighting our recent projects progress by our students on the #aging Hallmarks in #blood revolving on #inflammation of stem cell.
1 more month to register for the "Annual Meeting of the German Association for #Aging Research". Taking place 27-28 June at IMB. ➡️ .#alternsforschung #ageingresearch
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Huge milestone in Single cell Characterization of #inflammatory #HSC in #CHIP and Clonal dynamics in #aging 🩸🧬Congratulations @pvyas_oxford @stephxie @ John Dick and all contributors on this fantastic endeavor in pushing forward our fundamentals in hematopoiesis 👏🏻👏🏻 🔬🇬🇧🇨🇦.
Excited to share:.Selective advantage of mutant stem cells in human clonal hematopoiesis is associated with attenuated response to inflammation and aging: Cell Stem Cell .Huge privilege to work colleagues in the lab and with Andy, Stephanie and John.
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